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Aliment Pharmacol Ther
Aliment Pharmacol Ther

... 3.39 h, respectively. Linear aggression analysis assessing the direct proportionality of AUC on the dose for the Canadian UDCA tablet gave an estimate of 0.063 + 0.0164 (standard error, P-value=0.0117), e.g. if the dose increases from 250 mg to 500 mg, the serum ursodeoxycholic acid increases by 250 ...
Sulfin® Tablets 100 mg
Sulfin® Tablets 100 mg

... 200-400 mg daily in two divided doses, with meals or milk, gradually increasing when necessary to full maintenance dosage in one week. Maintenance 400 mg daily, given in two divided doses, as above. This dosage may be increased to 800 mg daily. If necessary and it may sometimes be reduce to as low a ...
Available Online through - International Journal of Pharmacy and
Available Online through - International Journal of Pharmacy and

... formulations was less than 1%, weight variation and drug content was found to be within official limits. Amongst all formulations, the optimized formulation F9 was prepared with Lycoat as a super disintegrant showed least disintegration time and faster dissolution. Key Words: Flupirtine, Fast-disint ...
ASMQ brochure
ASMQ brochure

... a Brazilian government-owned pharmaceutical company, and, following a South-South technology transfer, with Cipla Ltd, an Indian pharmaceutical company. ASMQ FDC, produced by Cipla Ltd, was prequalified by WHO in September 2012, a recognition of the product’s quality and an important step in acceler ...
Protonil Tablet - Renata Limited
Protonil Tablet - Renata Limited

... Lactating mother: There are no data on the excretion of Pantoprazole into the breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother. Pregnant women: No data are available on administration of pantop ...
fast dissolving tablets: preparation, characterization and evaluation
fast dissolving tablets: preparation, characterization and evaluation

... disintegrate in the oral cavity have attracted a great deal of attention2. United States Food and drug administration (FDA) defined fast dissolving tablet (FDT) as “a solid dosage form containing medicinal substance or active ingredient which disintegrate rapidly usually within a matter of seconds w ...
The Need and Importance of Dose Flexibility - Accu
The Need and Importance of Dose Flexibility - Accu

... Tablets, on the other hand, are the most popular dosage form because of the advantages afforded to both the manufacturer and the patient.8 They also offer the greatest opportunity for dose flexibility via the presence of a score mark. It is estimated that over 50% of all oral dosage forms are produc ...
USF Research Day Poster (Jeff Burgess)
USF Research Day Poster (Jeff Burgess)

... This study will focus on acetaminophen (APAP), which is an analgesic used for mild pain. This drug may be used to treat pathologies, such as acute mild pain, chronic mild pain, fever, and osteoarthritis. Its mechanism of action is not fully understood, but it is believed to demonstrate some NSAID-li ...
CORRELATION BETWEEN COMPACTION AND DISSOLUTION OF METOPROLOL TARTARATE
CORRELATION BETWEEN COMPACTION AND DISSOLUTION OF METOPROLOL TARTARATE

... formulation particularly by direct compression method. Direct compression has several advantages over wet granulation particularly by saving time and money. Choice of binder in designing formulation by direct compression must fulfill certain requirements such as, good binding ability with required d ...
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article

... Formulation  Ltd.  Haridwar  (PFL)  and  HPMC  K4M,  Ethylcellulose,  Polyvinyl pyrrolidone k‐30 & Sodium alginate were also gift sample  from Pharmasynth Formulation Ltd. Haridwar (PFL).  ...
orodispersible_dosage_forms
orodispersible_dosage_forms

... and process parameters by using hydrochlorthiazide as a model drug on the basis of which US Patent 6,010,719 was granted. Tablets prepared by lyophilization, are fragile and possess low mechanical strength, which make them difficult to handle and they also exhibit poor stability on storage under str ...
amoxicillin/clavulanate - DavisPlus
amoxicillin/clavulanate - DavisPlus

... and ALT concentrations. Elderly men and patients receiving prolonged treatment are atqrisk for hepatic dysfunction. May cause false-positive direct Coombs’ test result. ...
Bulletin #115
Bulletin #115

... fails to respond or if there is loss of response to the first agent. Requests for coverage for this indication must be made by the rheumatologist. A second application would also be required after 12 weeks to assess and would need to show an improvement to the patient’s condition on either of these ...
Timotor - Square Pharmaceuticals Ltd.
Timotor - Square Pharmaceuticals Ltd.

... For adults: 100mg-200mg, 3 times per day before meals. ADVERSE REACTIONS Trimebutine maleate is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/c ...
Trulance™ - plecanatide
Trulance™ - plecanatide

... M – Metabolized in the GI tract to an active metabolite by low of the terminal leucine moiety; both plecanatide and the metabolite are proteolytically degraded within the intestinal lumen to smaller peptides and ...
Year 2013 - Central Drugs Standard Control Organization
Year 2013 - Central Drugs Standard Control Organization

... multidrug resistant enteric fever only ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
International Journal for Pharmaceutical Research Scholars (IJPRS)

... fact which leads to poor patient compliance. To overcome this drawback, fast dissolving tablets (FDT) has emerged as alternative oral dosage forms. These are novel types of tablets that disintegrate in saliva within few seconds without chewing and additional water. According to European Pharmacopoei ...
705 Quality Attributes of Tablets Labeled as Having a Functional
705 Quality Attributes of Tablets Labeled as Having a Functional

... 705 Quality Attributes of Tablets Labeled as Having a Functional Score. The General Chapters—Dosage Forms Expert Committee proposes to add a new general test chapter to ensure the quality attributes of functionally scored tablets during their time in the marketplace. The tests provided in this new g ...
sugar coating
sugar coating

... placed in the core and the other(s) in the coating layer. However, there is still an interface contact left between the two layers. In cases where even this is important then the process of pre coating can be taken one stage further. It is possible to apply two press coatings to a tablet core using ...
Tolmic - Beximco Pharmaceuticals Ltd.
Tolmic - Beximco Pharmaceuticals Ltd.

... Controlled studies in pregnant women are not available. As is the case with the use of other NSAIDs, tolfenamic acid should not be given in the last trimester, due to risks of premature closure of the ductus arteriosus and prolonged parturition. In lactation: Tolfenamic acid is excreted to such a ve ...
FORMULATION DEVELOPMENT AND EVALUATION OF CHEWABLE TABLET OF
FORMULATION DEVELOPMENT AND EVALUATION OF CHEWABLE TABLET OF

... absorbance of the resulting solution at the γ max of 309 nm, Calculated the content of albendazole taking 742 as the specific absorbance at 309 nm. In vitro dissolution test [9] ...
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   

... Patient compliance is a prerequisite for the success of any drug delivery system which culminated into the design of mouth dissolving drug delivery  system beside older NDDS. Cetirizine dihydrochloride is a non‐sedative antihistamine with potent antiallergic action. The purpose of this study was  to ...
PHAN2HGY
PHAN2HGY

... Tablet shape is always an issue They are suitable for formulating non-potent drugs Loose powder on surface may lead to cross-contamination of products The tablet can be compressed from either powder or granules Drug release from these tablets can be immediate, controlled or targeted ...


... products to the market. Periostat tablets offer patients a significant advan over the current capsule formulation, as they are smaller and easier to swallow. Tablets can be manufactured at a lower cost than capsules, and w expect to experience improvements in our gross margin after the tablets a lau ...
Enhancing Solubility And Dissolution Rate of A Poorly
Enhancing Solubility And Dissolution Rate of A Poorly

... promising results in improving solubility, wettability, dissolution rate of drug and subsequently its bioavailablity2 .Co-grinding is one of the solid dispersion techniques which is superior to other approaches from economical as well as environmental stand points, in that unlike similar methods it ...
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Tablet (pharmacy)



A tablet is a pharmaceutical dosage form. Tablets may be defined as the solid unit dosage form of medicament or medicaments with or without suitable diluents and prepared either by molding or by compression. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.The compressed tablet is the most popular dosage form in use today. About two-thirds of all prescriptions are dispensed as solid dosage forms, and half of these are compressed tablets. A tablet can be formulated to deliver an accurate dosage to a specific site; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally. The tablet is just one of the many forms that an oral drug can take such as syrups, elixirs, suspensions, and emulsions. Medicinal tablets were originally made in the shape of a disk of whatever color their components determined, but are now made in many shapes and colors to help distinguish different medicines. Tablets are often stamped with symbols, letters, and numbers, which enable them to be identified. Sizes of tablets to be swallowed range from a few millimeters to about a centimeter.
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