- The Journal of Clinical Investigation
... members of the heterodimeric glycoprotein hormone family. The common α subunit forms noncovalent heterodimers with different β subunits. Two novel human glycoprotein hormonelike genes, α2 (A2) and β5 (B5), recently have been identified. Using a yeast two-hybrid assay, the two subunits were found as ...
... members of the heterodimeric glycoprotein hormone family. The common α subunit forms noncovalent heterodimers with different β subunits. Two novel human glycoprotein hormonelike genes, α2 (A2) and β5 (B5), recently have been identified. Using a yeast two-hybrid assay, the two subunits were found as ...
Once-daily administration of CJC-1295, a long-acting
... (CJC/24 h; n ⫽ 8), 48 h (CJC/48 h; n ⫽ 8), and 72 h (CJC/72 h; n ⫽ 7). Two placebo (pbo)-treated groups (treated daily) were included to allow comparison with the active treated animals: GHRHKO mice (GHRHKO/pbo; n ⫽ 8) and mice HTZ for the GHRHKO allele that have normal growth parameters (HTZ/pbo). ...
... (CJC/24 h; n ⫽ 8), 48 h (CJC/48 h; n ⫽ 8), and 72 h (CJC/72 h; n ⫽ 7). Two placebo (pbo)-treated groups (treated daily) were included to allow comparison with the active treated animals: GHRHKO mice (GHRHKO/pbo; n ⫽ 8) and mice HTZ for the GHRHKO allele that have normal growth parameters (HTZ/pbo). ...
Large height gain by growth hormone therapy in combination with
... 0.8 to 6.7 mU/liter after 20 min, which was considered as a subnormal response. Prolactin increased from 3.6 to 21 μg/liter (normal). Computed tomography at the age of 15 yr showed an empty sella, which was confirmed on the magnetic resonance imaging scan at 23 yr of age. At the age of 15 yr GH treat ...
... 0.8 to 6.7 mU/liter after 20 min, which was considered as a subnormal response. Prolactin increased from 3.6 to 21 μg/liter (normal). Computed tomography at the age of 15 yr showed an empty sella, which was confirmed on the magnetic resonance imaging scan at 23 yr of age. At the age of 15 yr GH treat ...
Hypothyroidism - Mid-Missouri Reproductive
... the thyroid gland is not producing enough thyroid hormone, the pituitary gland responds by producing more TSH. An elevated blood TSH level usually means the thyroid gland is not making enough thyroid hormone. Other blood tests include measuring T4 and thyroid autoantibodies. An autoantibody is an an ...
... the thyroid gland is not producing enough thyroid hormone, the pituitary gland responds by producing more TSH. An elevated blood TSH level usually means the thyroid gland is not making enough thyroid hormone. Other blood tests include measuring T4 and thyroid autoantibodies. An autoantibody is an an ...
PDF
... hormone ␣-subunit genes in cotransfection studies. Furthermore, TR2spl showed dominant negative activity against the wild-type TR2. These findings strongly suggest that aberrant alternative splicing of TR2 mRNA generated an abnormal TR protein that accounted for the defective negative regulation ...
... hormone ␣-subunit genes in cotransfection studies. Furthermore, TR2spl showed dominant negative activity against the wild-type TR2. These findings strongly suggest that aberrant alternative splicing of TR2 mRNA generated an abnormal TR protein that accounted for the defective negative regulation ...
31 role of prolactin and somatolactin in calcium regulation in fish
... In mammals, endocrine control of calcium regulation is performed by hyper- and hypocalcaemic hormones (Wendelaar Bonga and Pang, 1991). It is well established that parathyroid hormone (PTH) and a vitamin D3 metabolite are hypercalcaemic hormones, whereas calcitonin exerts a hypocalcaemic action. Fis ...
... In mammals, endocrine control of calcium regulation is performed by hyper- and hypocalcaemic hormones (Wendelaar Bonga and Pang, 1991). It is well established that parathyroid hormone (PTH) and a vitamin D3 metabolite are hypercalcaemic hormones, whereas calcitonin exerts a hypocalcaemic action. Fis ...
Description of the thyroid hormone resistance syndrome illustrated
... Pituitary RTH can easily be misdiagnosed as hyperthyroidism [13]. Actually, there are cases wrongly using I treatment as in our case [14, 15]. There are also some other cases of RTH which were treated with I [5, 13, 16]. At present, we could not nd any reports about TSH dynamic changes after I treat ...
... Pituitary RTH can easily be misdiagnosed as hyperthyroidism [13]. Actually, there are cases wrongly using I treatment as in our case [14, 15]. There are also some other cases of RTH which were treated with I [5, 13, 16]. At present, we could not nd any reports about TSH dynamic changes after I treat ...
THYROID FUNCTION IN ME – IS THERE A MAJOR DIAGNOSTIC
... production. Additionally they increase the heart rate, cardiac output, alter body temperature and ventilation rates in support of these activities. Other effects on the brain and skeleton are essential to normal growth and development. A patient who is seriously deficient in thyroid hormones will us ...
... production. Additionally they increase the heart rate, cardiac output, alter body temperature and ventilation rates in support of these activities. Other effects on the brain and skeleton are essential to normal growth and development. A patient who is seriously deficient in thyroid hormones will us ...
what`s it all about…
... Children use much of their energy to grow, so children with hypothyroidism don’t grow well. I am sure there are people suffering with hypothyroidism thinking, “I wish I had hyperthyroidism so I could lose weight.” Don’t envy them. Hyperthyroidism is actually a much more serious problem than hypothyr ...
... Children use much of their energy to grow, so children with hypothyroidism don’t grow well. I am sure there are people suffering with hypothyroidism thinking, “I wish I had hyperthyroidism so I could lose weight.” Don’t envy them. Hyperthyroidism is actually a much more serious problem than hypothyr ...
The Free Hormone Hypothesis and
... between ‘if4 index” methods and genuine f’F4 assays (20), although the present basis for this classification is somewhat illogical: some of the most reliable if4 assay methods, such as the one developed by Ross and Benraad (21), fall within the association’s definition of an if4 index. Whether or no ...
... between ‘if4 index” methods and genuine f’F4 assays (20), although the present basis for this classification is somewhat illogical: some of the most reliable if4 assay methods, such as the one developed by Ross and Benraad (21), fall within the association’s definition of an if4 index. Whether or no ...
establishment of reference values for endocrine tests. Part Vii
... patients for suspected GH deficiency is essential. For, in case of a false-positive diagnosis, the patient will be subjected to a prolonged and expensive treatment, whereas a false-negative diagnosis will deprive the patient of treatment. To identify patients appropriately, there is a need for relia ...
... patients for suspected GH deficiency is essential. For, in case of a false-positive diagnosis, the patient will be subjected to a prolonged and expensive treatment, whereas a false-negative diagnosis will deprive the patient of treatment. To identify patients appropriately, there is a need for relia ...
Endocrine Effects of Marijuana
... metabolism. Their synthesis and secretion are regulated by thyroid-stimulating hormone (TSH) from the anterior pituitary, which in turn is controlled by thyrotropin-releasing hormone (TRH). Cannabinoid effect on thyroid function was first noted in 1965, when marijuana extract was shown to reduce iod ...
... metabolism. Their synthesis and secretion are regulated by thyroid-stimulating hormone (TSH) from the anterior pituitary, which in turn is controlled by thyrotropin-releasing hormone (TRH). Cannabinoid effect on thyroid function was first noted in 1965, when marijuana extract was shown to reduce iod ...
Article PDF
... interaction was noted (P = 0.39), with GH for both test days increasing over time. However, a more robust increase was noted for test 2 as compared to test 1, as evidenced by a test day effect (P = 0.02). A time effect was also noted (P = 0.01). Contrasts revealed that values were higher at 60 mi ...
... interaction was noted (P = 0.39), with GH for both test days increasing over time. However, a more robust increase was noted for test 2 as compared to test 1, as evidenced by a test day effect (P = 0.02). A time effect was also noted (P = 0.01). Contrasts revealed that values were higher at 60 mi ...
Hypothyroidism in Pregnancy
... 31 % with anti-TPO antibody (Casey BM, 2007) More common on women with autoimmune diseases 50 % hypothyroidism in 8 years May cause childhood IQ decrease Increase in preterm 4% vs 2.5% in euthyroid mother (Casey BM, 2007) ...
... 31 % with anti-TPO antibody (Casey BM, 2007) More common on women with autoimmune diseases 50 % hypothyroidism in 8 years May cause childhood IQ decrease Increase in preterm 4% vs 2.5% in euthyroid mother (Casey BM, 2007) ...
physiology – endocrine system
... D. Corticosteroids are excreted completely by urinary route E. All of the above 41. Which of the following is TRUE regarding androgens? A. In male, 2/3 of urinary ketosteroid is from testicular origin. B. Adrenal androgens only have 20% activity of testosterone. C. Adrenal androgen production is con ...
... D. Corticosteroids are excreted completely by urinary route E. All of the above 41. Which of the following is TRUE regarding androgens? A. In male, 2/3 of urinary ketosteroid is from testicular origin. B. Adrenal androgens only have 20% activity of testosterone. C. Adrenal androgen production is con ...
Hypophysis and Hypothalamus
... The adenohypophysis produces six established hormones: thyroid stimulating hormone (TSH), corticotropin (ACTH), growth hormone (GH), sexual stimulating hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and prolactin (PRL). The first five serve tropic functions by stimulating ...
... The adenohypophysis produces six established hormones: thyroid stimulating hormone (TSH), corticotropin (ACTH), growth hormone (GH), sexual stimulating hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and prolactin (PRL). The first five serve tropic functions by stimulating ...
Medical Causes of Hypothyroidism
... exposure to medical treatments, and autoimmune disorders. It is common knowledge that hypothyroidism can arise from a chronic thyroid disease known as Hashiloto’s thyroiditis. This ailment is characterized by thyroid glands that are inflamed or enlarged. This inflammation can be responsible for the ...
... exposure to medical treatments, and autoimmune disorders. It is common knowledge that hypothyroidism can arise from a chronic thyroid disease known as Hashiloto’s thyroiditis. This ailment is characterized by thyroid glands that are inflamed or enlarged. This inflammation can be responsible for the ...
High-Resolution MR Imaging of Microadenomas at 1.5 T
... disease were evaluated retrospectively in a blinded fashion. The MR interpretation was compared with detailed operative diagrams and operative and pathologic reports. The examinations were performed on a 1.5-T MR system with thin-section sagittal and coronal T1-weighted (short TR/TE) images. Each pi ...
... disease were evaluated retrospectively in a blinded fashion. The MR interpretation was compared with detailed operative diagrams and operative and pathologic reports. The examinations were performed on a 1.5-T MR system with thin-section sagittal and coronal T1-weighted (short TR/TE) images. Each pi ...
Derived copy of The Thyroid Gland
... of the thyroid gland is the more common cause of low blood levels of thyroid hormones. Called hypothyroidism, the condition is characterized by a low metabolic rate, weight gain, cold extremities, constipation, reduced libido, menstrual irregularities, and reduced mental activity. In contrast, hyper ...
... of the thyroid gland is the more common cause of low blood levels of thyroid hormones. Called hypothyroidism, the condition is characterized by a low metabolic rate, weight gain, cold extremities, constipation, reduced libido, menstrual irregularities, and reduced mental activity. In contrast, hyper ...
- Equine Reproduction Concepts
... and associates (1974) removed the thyroid gland from mares in an attempt to find resulting effects on reproductive function. No abnormalities were found. A later study by Lowe and coworkers (1987) confirmed that LH and progesterone concentrations, length of the estrous cycle and pregnancy rates were ...
... and associates (1974) removed the thyroid gland from mares in an attempt to find resulting effects on reproductive function. No abnormalities were found. A later study by Lowe and coworkers (1987) confirmed that LH and progesterone concentrations, length of the estrous cycle and pregnancy rates were ...
NME2.30 - Thyroid
... The bow-tie-shaped thyroid gland is situated in the anterior neck across the front of the trachea o It consists of left and right lobes and an isthmus (‘connecting branch’) o It normally weighs 10-20g The thyroid produces thyroid hormones that are: o The only hormones that require an essential trace ...
... The bow-tie-shaped thyroid gland is situated in the anterior neck across the front of the trachea o It consists of left and right lobes and an isthmus (‘connecting branch’) o It normally weighs 10-20g The thyroid produces thyroid hormones that are: o The only hormones that require an essential trace ...
TSH - Blood chemistry analysis
... intrinsic to the thyroid gland itself. TSH levels will be elevated. When TSH levels are decreased the problem may be reflective of a hyperthyroid state. Also consider that the problem may be due to abnormalities outside the thyroid in the pituitary-hypothalamic axis, which cause a secondary and even ...
... intrinsic to the thyroid gland itself. TSH levels will be elevated. When TSH levels are decreased the problem may be reflective of a hyperthyroid state. Also consider that the problem may be due to abnormalities outside the thyroid in the pituitary-hypothalamic axis, which cause a secondary and even ...
Inappropriate Secretion of TSH Syndrome
... clinically hyperthyroid, while RTH patients are generally euthyroid (so-called generalized RTH). However, in a minority of RTH thyrotoxic patients, features have been described with such individuals being deemed to have predominant central or pituitary resistance. Although incidence of inappropriate ...
... clinically hyperthyroid, while RTH patients are generally euthyroid (so-called generalized RTH). However, in a minority of RTH thyrotoxic patients, features have been described with such individuals being deemed to have predominant central or pituitary resistance. Although incidence of inappropriate ...
Thyroid Diseases
... Causes of hyperthyroidism • Graves Disease most common where they present very similarly to adults. • Overtreatment with thyroxin; therefore, close monitoring of dosage in hypothyroidism. • Thyroid adenoma (rare) • Transient neonatal thyrotoxicosis: when the mother has graves disease her antibodies ...
... Causes of hyperthyroidism • Graves Disease most common where they present very similarly to adults. • Overtreatment with thyroxin; therefore, close monitoring of dosage in hypothyroidism. • Thyroid adenoma (rare) • Transient neonatal thyrotoxicosis: when the mother has graves disease her antibodies ...
Hypopituitarism
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. If there is decreased secretion of most pituitary hormones, the term panhypopituitarism (pan meaning ""all"") is used.The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment. Most hormones controlled by the secretions of the pituitary can be replaced by tablets or injections. Hypopituitarism is a rare disease, but may be significantly underdiagnosed in people with previous traumatic brain injury. The first description of the condition was made in 1914 by the German physician Dr Morris Simmonds.