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A Functional Approach to Hypothyroidism
A Functional Approach to Hypothyroidism

... • MTF is associated with a 2.2 fold increased risk of coronary artery disease and 1.5 fold increase in risk of cardiovascular mortality • Treatment can result in: – Significant reduction in cholesterol levels – Lowering risk of arthrosclerosis, myocardial infarction, coronary artery disease andcardi ...
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Adrenal Cortex

... Screening tests-3 Loss of normal cortisol suppression by dexamethazone By: Overnight dexamethazone suppression test Principle of the test Dexamethasone act as an exogenous cortisol substitute that suppresses endogenous cortisol secretion if adrenal cortex is normal (through suppressing ACTH if ant. ...
Hypothyroidism in children: diagnosis and treatment R A EVIEW
Hypothyroidism in children: diagnosis and treatment R A EVIEW

... Objective: To present relevant and updated information on the status of hypothyroidism in the pediatric population (newborn infants to adolescents). Sources: Original and review articles and books containing relevant updated data. Summary of the findings: This review addressed data on the etiopathog ...
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Mouse/Rat Adrenocorticotropic Hormone (ACTH) Ultra Sensitive
Mouse/Rat Adrenocorticotropic Hormone (ACTH) Ultra Sensitive

... goat polyclonal antibody to ACTH, purified by affinity chromatography, and a mouse monoclonal antibody to ACTH are specific for well-defined regions on the ACTH molecule. One antibody is prepared to bind only the C-terminal ACTH 34-39 and this antibody is biotinylated. The other antibody is prepared ...
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Production, Regulation, and Action of Thyroid Hormones

... • Critical for normal CNS neuronal development • Enhances wakefulness and alertness • Enhances memory and learning capacity • Required for normal emotional tone • Increase speed and amplitude of peripheral ...
Adrenal glands
Adrenal glands

... Corticotrophin releasing hormone (CRH) is injected, and cortisol and ACTH levels are measured at baseline (before CRH) and at timed intervals after the injection, for example at 30 and 60 minutes. The normal response is a peak in ACTH levels followed by a peak in cortisol levels. Most patients with ...
Thyroid Gland
Thyroid Gland

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The thyroid gland
The thyroid gland

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THYROID STIMULATING HORMONE (TSH) ENZYME
THYROID STIMULATING HORMONE (TSH) ENZYME

... secreted from the anterior pituitary, is generally regarded as the most sensitive indicator available for the diagnosis of primary and secondary (pituitary) hypothyroidism (1,2). Increase in serum concentrations of TSH, which is primarily responsible for the synthesis and release of thyroid hormones ...
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MARA UNIVERSITY OF TECHNOLOGY FACULTY OF HEALTH
MARA UNIVERSITY OF TECHNOLOGY FACULTY OF HEALTH

... Therefore, hyperthyroidism happened when too much thyroid hormones triggered and spread in our body. According to Wikipedia.org, hyperthyroidism usually begins slowly. At first, the symptoms may be mistaken for simple nervousness due to stress. If one has been trying to lose weight by dieting, one m ...
Clin Endocrinol 2006, 65 - Associazione Medici Endocrinologi
Clin Endocrinol 2006, 65 - Associazione Medici Endocrinologi

... levels can also be elevated in patients with chronic renal or hepatic failure, usually due to decreased clearance of PRL. The polycystic ovarian syndrome is commonly associated with elevated PRL levels as well.10 Some patients with primary hypothyroidism have mild hyperprolactinaemia. It has been pr ...
Resistance to thyroid hormone due to defective thyroid receptor alpha
Resistance to thyroid hormone due to defective thyroid receptor alpha

... effects and development of the central nervous system (Table 1). TH synthesis is controlled by hypothalamic thyrotropin-releasing hormone (TRH) and pituitary thyroid stimulating hormone (TSH) and, in turn, T4 and T3 regulate TRH and TSH synthesis as part of a negative feedback loop. These physiologi ...
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Prolactin and Infertility

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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... glands. Humoral and cell-mediated immune mechanisms are implicated in causing cellular damage and inflammatory reactions in the thyroid gland. Laboratory test commonly used for measuring thyroid antibodies are for thyropreoxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb and thyroid recepto ...
Tài liệu PDF
Tài liệu PDF

... blood glucose levels and the accumulation of lipid deposits on the face and neck. It is caused by hypersecretion of cortisol. The most common source of Cushing’s disease is a pituitary tumor that secretes cortisol or ACTH in abnormally high amounts. Other common signs of Cushing’s disease include th ...
Thyroid Disease
Thyroid Disease

... To know the common causes of hypo and hyperthyroidism To recognise the signs and symptoms associated with hypo and hyperthyroidism To understand TFT interpretation To know the management for hypo and hyperthyroidism Important complications associated with these Thyroid cancers ...
Thyroid hormone resistance (THR): a case report
Thyroid hormone resistance (THR): a case report

... response to thyroid hormones. Thyroid function tests often show T3 and T4 elevation, with normal or elevated TSH concentration. Sensitivity to thyroid hormone is variable in different organs, and clinical presentation, heterogeneous2,15; isolated central presence of the RTH syndrome has even been de ...
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Hypopituitarism



Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. If there is decreased secretion of most pituitary hormones, the term panhypopituitarism (pan meaning ""all"") is used.The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment. Most hormones controlled by the secretions of the pituitary can be replaced by tablets or injections. Hypopituitarism is a rare disease, but may be significantly underdiagnosed in people with previous traumatic brain injury. The first description of the condition was made in 1914 by the German physician Dr Morris Simmonds.
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