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Emerging treatments in Crohn*s disease and ulcerative colitis
Emerging treatments in Crohn*s disease and ulcerative colitis

... manner in which a physician may use an approved drug. Once a product has been approved for marketing, a physician may prescribe it for uses or in treatment regimens or patient populations that are not included in approved labeling. Such “unapproved” or, more precisely, “unlabeled” uses may be approp ...
Pharmacology - aztraumacenter
Pharmacology - aztraumacenter

... 0.02 – 0.06 mg/kg q 2-6 hrs 0.01 – 0.04 mg/kg q 2-6 hrs Use vecuronium ...
Medication Management of Early Psychosis and Ultra
Medication Management of Early Psychosis and Ultra

... • Attenuated positive symptom state: Non-psychotic, predelusional unusual thought content; pre-hallucinatory perceptual abnormalities; or subthreshold disorganization of speech. • Brief intermittent psychotic state: Psychotic symptoms emerging in the recent past that are too brief to meet criteria f ...
Metacam Risks in Cats
Metacam Risks in Cats

... Metacam Solution for Injection (for cats) and Metacam Oral Suspension (for dogs). Metacam’s FDA Approval Status Metacam Solution for Injection was approved for one-time use only in cats on 28 Nov 2004 (NADA 141-219). Metacam Oral Suspension was approved for dogs only on 15 Apr 2003 (NADA 141-213). A ...
Antihypertensive agents
Antihypertensive agents

... -rejection from smoking and alcohol; -increasing of physical activity; -restriction of salt consumption (less than 6 g per day); -decreasing of body weight in a case of obesity. 3. Scheme of drug treatment should be the most availably simple – 1 tablet per day if possible; it is better to use drugs ...
Antiinfective drugs
Antiinfective drugs

... antibiotics across the cell membrane.They are effective against most gramnegative and many gram-positive bacteria. Side effects: Include serious side effects, such as nephrotoxicity, ototoxicity and neuromuscular synaptic dysfunction. Diarrhea may occur due to distruption of bacterial flora. Clinica ...
niLOtinib Monograph
niLOtinib Monograph

... Mutagenicity: Not mutagenic in bacterial in vitro systems and in mammalian in vitro and in vivo mutation tests. Unknown if clastogenic. ...
Significant Drug Interactions with Tuberculosis Medications
Significant Drug Interactions with Tuberculosis Medications

... Warfarin is metabolized mainly by CYP2C9 and this path is inhibited weakly by isoniazid- could increase the drug level of warfarin › Possible but highly unlikely-little reports in literature › consider reducing the dose of Warfarin , during treatment with Isoniazid › Monitor prothrombin activity and ...
Pretin D Prescribing Information
Pretin D Prescribing Information

... for 2 weeks after stopping use of an MAO inhibitor. The antihypertensive effects of β adrenergic blocking agents, Methyldopa, Reserpine, and Veratrum alkaloids may be reduced by sympathomimetics. Increased ectopic pacemaker activity can occur when Pseudoephedrine is used ...
azathioprine / 6 mercaptopurine - British Society of Gastroenterology
azathioprine / 6 mercaptopurine - British Society of Gastroenterology

... There are very few case reports of an association between cervical cancer and IBD patients taking azathioprine, although there is more evidence available for patients with rheumatoid arthritis or systemic lupus erythematosus. There are occasional reports of IBD patients on immunosuppressive therapy ...
Chapter 41 Tetracyclines and chloramphenicol
Chapter 41 Tetracyclines and chloramphenicol

... serious hazard so limit use (The risk of aplastic anemia does not contraindicate the use of chloramphenicol in situations in which it is necessary; however, it emphasizes that the drug should never be employed in undefined situations or in diseases readily, safely, and effectively treatable with oth ...
P vivax
P vivax

... Adverse Effects ...
E7Step4
E7Step4

... should be represented sufficiently to permit the comparison of drug response in them to that of younger patients. For drugs used in diseases not unique to, but present in, the elderly a minimum of 100 patients would usually allow detection of clinically important differences. For drugs to treat rela ...
11-15-04 Anti-infective Agents short form
11-15-04 Anti-infective Agents short form

... • 1st generation drugs are effective against most common Gm(+) and Gm(-) bacteria • 2nd, 3rd, and 4th generation cephalosporins have increasing activity against Gm(-) bacteria • Cephalosporins are the drugs of choice for infections caused by Klebsiella pneumoniae • Cephalosporins are more resistant ...
What is polypharmacy
What is polypharmacy

... with cranberry juice? Answer Cranberries, particularly in the form of cranberry juice, have been used widely for several decades for the prevention of urinary tract infections. A Cochrane review,3 published in 1998, found four trials of reasonable design (three cross-over, one parallel group) to inc ...
Tranxene (clorazepate)
Tranxene (clorazepate)

... Tranxene (clorazepate) is a benzodiazepine indicated for treatment of anxiety disorders or short-term relief of symptoms of anxiety, alcohol withdrawal, and seizure disorders. The use of a drug for its approved indications is called its labeled use. In clinical practice, however, physicians often pr ...
Pharmacological Management of Type 2 Diabetes (excluding insulin
Pharmacological Management of Type 2 Diabetes (excluding insulin

... -Metformin is the first line treatment for patients with type 2 diabetes -To minimise GI side effects, increase dose gradually over weeks and ensure tablets are taken with meals -Modified release: reserved for those who suffer with persistent GI side effects only after gradual titration with immedia ...
Express Scripts Drug Information & Wellness Center Drug Information Updates
Express Scripts Drug Information & Wellness Center Drug Information Updates

...  FDA warrants a careful screening of patients for azithromycin due to the risk of potentially fatal irregular heart rhythm.  Patients at risk for azithromycin-induced arrhythmia include individuals who already have a prolonged QT interval, low blood levels of potassium or magnesium, abnormally s ...
Casodex drug insert
Casodex drug insert

... relevant to the indicated patient population. A small increase in the incidence of hepatocellular carcinoma in male mice given 75 mg/kg/day of bicalutamide (approximately 4 times human therapeutic concentrations*) and an increased incidence of benign thyroid follicular cell adenomas in rats given 5 ...
Drugs used in the treatment of Angina Pectoris
Drugs used in the treatment of Angina Pectoris

... - clonidine lowers heart rate and cardiac output more than does methyldopa. - Reduction in arterial blood pressure by clonidine and methyldopa is accompanied by decreased renal vascular resistance and maintenance of renal blood flow. - Adverse effects: Dry mouth and sedation , should not be given to ...
Full Prescribing Information
Full Prescribing Information

... Pregnancy Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. It is unknown whether VASCEPA can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. VASCEPA should be used during pregnancy only if the potential benefit to ...
more
more

... a-Polyene antibiotics: 1-Amphotericin: In spite of its toxic potential, amphotericin B is the drug of choice for the treatment of life-threatening, systemic mycoses. The drug is also sometimes used in combination with flucytosine so that lower (less toxic) levels of amphotericin B are possible. Mech ...
AMIRAN
AMIRAN

... excreted in human milk. Because the potential for hypoglycemia in nursing infants may exist, Glimepiride should be discontinued in nursing mothers. If Glimepiride is discontinued, and if diet and exercise alone are inadequate for controlling blood glucose, insulin therapy should be considered. Pedia ...
Halocur 0.5 mg/ml oral solution for calves Introduction Company
Halocur 0.5 mg/ml oral solution for calves Introduction Company

... Administration should start in the first 24 to 48 hours of age. - Reduction of diarrhoea due to diagnosed Cryptosporidium parvum. Administration should start within 24 hours after the onset of diarrhoea. In both cases, the reduction of oocysts excretion has been demonstrated. ...
Medication Alternatives for the Elderly
Medication Alternatives for the Elderly

... No preferred agents exist within the drug class. Perform risk-benefit determination prior to use. Lower doses should be used and patients should be monitored due to the increased potential for side effects. ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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