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31.4 Immunity and Technology KEY CONCEPT help keep a person healthy.
31.4 Immunity and Technology KEY CONCEPT help keep a person healthy.

... • Antiseptics kill pathogens outside of the body. – do not target specific pathogens – examples include vinegar and soap • Antibiotics kill pathogens inside the body. – target one specific bacterium or fungus – not effective against viruses ...
NIAID/GSK Experimental Ebola Vaccine Appears Safe, Prompts
NIAID/GSK Experimental Ebola Vaccine Appears Safe, Prompts

... of immune system cells called T cells. A recent study by VRC scientist Nancy J. Sullivan, Ph.D., and colleagues showed that non-human primates inoculated with the candidate NIAID/GSK vaccine developed both antibody and T-cell responses, and that these were sufficient to protect vaccinated animals fr ...
(rVSV) Vaccines for Cancer Immunotherapy
(rVSV) Vaccines for Cancer Immunotherapy

... of oncolytic vaccines targeting different cancer indications, potentially in combination with other cancer immunotherapies such as checkpoint inhibitors, or other forms of therapy such as chemotherapy and newer targeted therapies. The companies anticipate the first program initiating human clinical ...
IB280 SEMINAR Dr. France-Isabelle Auzanneau, Professor, Department of Chemistry, University of Guelph
IB280 SEMINAR Dr. France-Isabelle Auzanneau, Professor, Department of Chemistry, University of Guelph

... surface of tumor cells (TACEs) or bacteria and their use as immunotherapeutics in the fight against cancer or bacterial infection. Here, I will describe a combination of synthetic carbohydrate chemistry and molecular modeling experiments are used to design anti-tumor vaccines based on the tumor asso ...
TOPIC: Immunity AIM: What is immunity?
TOPIC: Immunity AIM: What is immunity?

... system fight disease? Do Now: 1. Explain 2 differences between an infectious and noninfectious disease. 2. Give an example of each. ...
医学史简论 (8) A Brief History of Medicine
医学史简论 (8) A Brief History of Medicine

... The details and credit for the discovery of its use as the antibiotic streptomycin were strongly contested by one of Waksman's graduate students, Albert Schatz, and resulted in litigation. The litigation ended with a substantial settlement for Schatz and the official decision that Waksman and Schatz ...
Cancer vaccines: up, down, … up again?
Cancer vaccines: up, down, … up again?

... During the efferent phase of the immune response, it is possible that the antitumor T cells may not have trafficked to the tumor site or if they trafficked, they may not have been able to overcome newly recognized immunosuppressive mechanisms present in the tumor microenvironment. However, indolent ...
The Immune System - Clark Pleasant Community School Corp
The Immune System - Clark Pleasant Community School Corp

... antibodies; the single most effective protection ...
Current vaccine approach (2)
Current vaccine approach (2)

... • Viruses such as chicken pox have a low level of mutation, so people obtain long-term immunity from exposure to the virus • Previous exposure to flu does not provide long-term protection because the virus mutates seasonally • Vaccines are developed to mimic the disease, tricking the immune system t ...
Why checkpoint inhibitors need help
Why checkpoint inhibitors need help

... Adoptive transfer of ex vivo expanded T cells has also shown encouraging results. However, these approaches are patientspecific, time-consuming and expensive. There is therefore still a need for a simple, safe and effective vaccine able to induce potent and specific killer T cells. We would argue th ...
The immune system of the body produces specific antibodies to kill a
The immune system of the body produces specific antibodies to kill a

... b. Complete the sentences with the words in the box below; the words may be used once, more than once or not at all. ...
Document
Document

... Palese 2002). Only a single round of replication can occur, with termination before the formation of infectious viral particles. Protein expression will result in an immune response, and there is no danger 26 of infection spreading to other cells or people. ...
Duramune® Lyme™+Max 5-CvK/4L
Duramune® Lyme™+Max 5-CvK/4L

... • 100 percent preventable fraction in a challenge study conducted recently for USDA requalification1 • Proven 92 percent effective against natural infection in a one-of-a-kind study conducted on real-world dogs in a highly endemic area2 — unprecedented proven efficacy among canine Lyme vaccines ...
H1N1 Just In Time Paramedic Vaccine Training 09-13-2009
H1N1 Just In Time Paramedic Vaccine Training 09-13-2009

...  Influenza virus vaccines induce humoral antibodies against hemagglutinins  These antibodies neutralize influenza viruses  A hemagglutinin inhibition titer greater than or equal to1:40 in the serum is considered to be protective  Influenza virus vaccines provide protection for the ongoing influe ...
dogs - kingedwardvet.co.za
dogs - kingedwardvet.co.za

... with or without fever or a localised swelling. In the UK, the Veterinary Products Committee reported vaccine reactions in 0.21-0.61/10 000 doses. As the VPC relied on voluntary reporting of adverse reactions by vets and industry, it appears likely that not all suspected vaccine reactions were report ...
Appendix S1. Calculation of the reproductive number using the next
Appendix S1. Calculation of the reproductive number using the next

... and the equations for the infectious compartments of the linearized system of the scaled model at ...
Interference of passive and active immunity after vaccination of pigs
Interference of passive and active immunity after vaccination of pigs

... the antigen specific proliferation of lymphocytes. In addition, we investigated the nature of protective immunity induced by systemic delivery of glycoprotein E (gE)-deleted attenuated vaccine (the Th1–Th2 polarization of immune response) by examining the profile of Th1 and Th2 cytokines produced by ...
Microbiology - NYCC SP-01
Microbiology - NYCC SP-01

... 35. Valley Fever is another name for which of the following fungal diseases? a. Histoplasmosis b. Asperilligosis c. Toxidiomycosis d. Blastomycosis 36. A fungal infection of the bearded area of the face might be: a. Tinea babare b. Tinea pedis c. Tinea crura d. Tinea capitis 37. A coat that surround ...
Tetanus - Pipestone Veterinary Services
Tetanus - Pipestone Veterinary Services

... There are two types of products available for protection. The first is tetanus toxoid. This is a vaccine which stimulates the animal to produce antibodies against the tetanus toxin. If a properly vaccinated animal gets a puncture wound it will have adequate antibodies to inactive the toxin and the s ...
A sweet trick for fighting infection
A sweet trick for fighting infection

... “tremendous success” but notes there could be room to improve further too. In some cases where the native bacterial structure can’t be used a synthetic structure produced in a chemistry lab is an attractive alternative. And it’s not just bacteria he has in his sights: he is also looking at how cleve ...
Vaccinia virus (VACV) is primarily known as a vaccine against its
Vaccinia virus (VACV) is primarily known as a vaccine against its

... Vaccinia virus (VACV) is primarily known as a vaccine against its relative variola virus, the causative agent of smallpox. In the seventies of the 20th century, the vaccination campaign with VACV led to eradication of smallpox. Consequently, vaccination of the general population was stopped. Current ...
year 8 vaccine information fact sheet (PDF 870KB)
year 8 vaccine information fact sheet (PDF 870KB)

... 85–100% effective in preventing the main types of HPV infection that cause cancers and genital warts. All females who have received the HPV vaccine will require regular screening for cervical cancer. ...
Duramune® Lyme™+Max 5-CvK - Boehringer Ingelheim Vetmedica
Duramune® Lyme™+Max 5-CvK - Boehringer Ingelheim Vetmedica

... Gentamicin and thimerosal added as preservatives. ...
Inactivated vaccines
Inactivated vaccines

... Delivery at the optimum time of life to prevent disease. Safe with no side effects. Stable (preferably long lasting on the shelf at ambient temperature) Cheap for mass production and dosing. ...
Prospects of new vaccines for resurgent and emergent diseases
Prospects of new vaccines for resurgent and emergent diseases

... based on whole inactivated bacteria, e.g. pertussis (whooping cough), or viruses. These whole cell vaccines are often reactogenic and contain antigens that do not contribute to a protective immune response. Tetanus and diphtheria vaccines were early examples of acellular vaccines, being based on fra ...
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Vaccine



A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing micro-organism and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and keep a record of it, so that the immune system can more easily recognize and destroy any of these micro-organisms that it later encounters.The administration of vaccines is called vaccination. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, the HPV vaccine, and the chicken pox vaccine. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world. The World Health Organization (WHO) reports that licensed vaccines are currently available to prevent or contribute to the prevention and control of twenty-five infections.Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by any natural or ""wild"" pathogen), or therapeutic (e.g., vaccines against cancer are also being investigated; see cancer vaccine).The terms vaccine and vaccination are derived from Variolae vaccinae (smallpox of the cow), the term devised by Edward Jenner to denote cowpox. He used it in 1798 in the long title of his Inquiry into the...Variolae vaccinae...known...[as]...the Cow Pox, in which he described the protective effect of cowpox against smallpox. In 1881, to honour Jenner, Louis Pasteur proposed that the terms should be extended to cover the new protective inoculations then being developed.
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