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Amsterdam Immunogenicity and Tolerance
Amsterdam Immunogenicity and Tolerance

... The team at EpiVax, Inc., led by Dr. Annie De Groot and Bill Martin, has pioneered the development of a set of immunoinformatics tools which allows researchers to predict the immunogenicity of peptides and proteins. The potential applications of this technology are vast: for instance, one could be t ...
File
File

... the last known person to die from smallpox- Contracted it from a medical school, thus all known stocks were destroyed except for the CDC’s ...
Place Invaders: Disease Travels
Place Invaders: Disease Travels

... Disease Travels ...
Document
Document

... C. Passive ...
IMAC response to “Just a Little Prick” by Peter and Hilary Butler
IMAC response to “Just a Little Prick” by Peter and Hilary Butler

... demonstrates increased rate of decline in pertussis mortality as a result of pertussis vaccination. Had the rate of decline continued as it had between 1900 and 1939 when pertussis vaccination was not undertaken in the US, there would have been approximately 8000 deaths between 1970-1974 compared to ...
introduction and overview
introduction and overview

... Identify the major principles of the human immune response Introduce the main forms of immune response. What they are and how do they relate to one another ? ...
Outbreak: A Webquest about Epidemics
Outbreak: A Webquest about Epidemics

... Is there a cure or a vaccine? What other ways can you prevent getting the disease? ...
The AIDS Vaccine.
The AIDS Vaccine.

... I’m Chris Blair and today our topic of interest is the progress of the aids vaccine. As it stands, over 34 million people are infected with AIDS, and the figure is rising; more people die from AIDS than almost any other infectious disease, including malaria and TB. Since the link between HIV and the ...
Defence against infections Immunisation
Defence against infections Immunisation

... Immunisation Edward Jenner ...
immunisation of children + staff policy
immunisation of children + staff policy

... Adults should receive a booster shot for tetanus and diphtheria vaccine (ADT) every 10 years. Staff are to follow infection control guidelines because vaccines, such as that for polio, contain a “live” virus that children can excrete in their stool in the fortnight following administering of the vac ...
Patient History - "Gigi" Doan, MD
Patient History - "Gigi" Doan, MD

... Where? ...
Overview of the Second Havemeyer EHV
Overview of the Second Havemeyer EHV

... identify vaccination technologies that can protect against the more important pathological sequelae to infection. For the first time there was a major discussion of the use of antiviral agents, in both experimental and clinical studies. The workshop participants agreed to participate in a multi-auth ...
Immune Activity Questions:
Immune Activity Questions:

... Immune Activity Questions: Questions: Attach your individual’s questions to the team’s project. 1. Discuss some of the ways microbes evade the body's immune system. 2. Distinguish between antigen and antibody. Then explain how antibodies and macrophages work together during an antigen-antibody react ...
The Immune System
The Immune System

... 1. Allergy- the immune system is overly sensitive to a foreign substance- something not normally found in the body.  Allergen- any substance that causes an allergy: dust, pollen, molds, some foods or medicines.  Histamine- chemical responsible for symptoms of allergies, like sneezing or watery eye ...
File
File

... 1. Allergy- the immune system is overly sensitive to a foreign substance- something not normally found in the body.  Allergen- any substance that causes an allergy: dust, pollen, molds, some foods or medicines.  Histamine- chemical responsible for symptoms of allergies, like sneezing or watery eye ...
Innate Immune Responses
Innate Immune Responses

... Innate Immune Responses to Vaccination • Few studies have examined innate responses in humans after vaccination (Querec et al., NI, 2009; Gaucher et al., JEM, 2008) • We implemented a clinical trial of an adenoviral vector HIV vaccine (Merck Ad5): 1. Which systemic innate immune responses can be me ...
Timely identification of optimal control strategies for emerging
Timely identification of optimal control strategies for emerging

... Results: Stage-specific infection rate estimates from cases hospitalized before quarantine began exceed those from the entire outbreak, but are qualitatively similar: infectiousness was negligible until symptom onset, and increased 10-fold from prodrome to acute illness. Given such information, autho ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

... • Natural infections persist within the body for a long time so the immune system has time to develop an effective response, vaccinations from dead m-os do not do this. • Less effective vaccines need booster injections to stimulate secondary responses ...
Clinical Signs are an Interaction of Host, Agent and the Environment
Clinical Signs are an Interaction of Host, Agent and the Environment

... case this is the pig, but more specifically the age group within a population is a particular concern. “Age” is a very important determinant of clinical expression because most diseases are noted in a specific age group. This is most often due to age-dependent changes in the level of immunity, or th ...
PRESS RELEASE Swiss biotech starts breakthrough anti
PRESS RELEASE Swiss biotech starts breakthrough anti

... The vaccine and the immune-booster are both being administered 6 times over a period of 8 weeks in this first clinical trial. About Cancer Immunotherapy Despite recent new cancer treatments, a majority of cancer patients with advanced or metastatic cancer still die from their disease within 5 years. ...
Topic 19 - Roslyn Public Schools
Topic 19 - Roslyn Public Schools

... of having a particular disease and recovering from it or from getting a vaccination for a particular disease – 1. vaccines – an injection of a weakened or deadened form of a disease causing microorganism that can no longer cause the disease but can still stimulate antibody production by white blood ...
Video: Understanding Viruses - Hutchison
Video: Understanding Viruses - Hutchison

... but strong enough to cause immunity. Chicken embryos are in ready supply and can be used to quickly produce large amounts of vaccine. 7. What is the difficulty with developing vaccines for RNA viruses? Give an example of a common RNA virus. RNA viruses change ftequently. New vaccines need to be deve ...
TUTORIAL 5 Multiple Choices For each of the questions below
TUTORIAL 5 Multiple Choices For each of the questions below

... An ELISA designed to test for the presence of serum antibody for a new strain of pathogenic bacteria is under development. Initially, a monoclonal antibody specific for a single epitope of the organism was used both to sensitize the wells of the ELISA plate and as the enzyme-labeled detecting antibo ...
TOPIC: Immunity AIM: What is immunity?
TOPIC: Immunity AIM: What is immunity?

... 1. They are produced by the body in response to the presence of foreign substances. 2. They may be produced in response to an antigen. 3. They are nonspecific, acting against any foreign substance in the body. 4. They may be produced by white blood cells. ...
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... Section B: HEPATITIS B VACCINATION DECLINATION I understand that due to my chance of occupational exposure to blood or other potential infectious materials I may be at risk of acquiring Hepatitis B infection. At this time I choose not to receive the Hepatitis B vaccine. Reason: _____________________ ...
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Vaccination



Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Vaccines can prevent or ameliorate morbidity from infection. When a sufficiently large percentage of a population has been vaccinated, this results in herd immunity. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, the HPV vaccine, and the chicken pox vaccine. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world. The World Health Organization (WHO) reports that licensed vaccines are currently available to prevent or contribute to the prevention and control of twenty-five infections.The active agent of a vaccine may be intact but inactivated (non-infective) or attenuated (with reduced infectivity) forms of the causative pathogens, or purified components of the pathogen that have been found to be highly immunogenic (e.g., outer coat proteins of a virus). Toxoids are produced for immunization against toxin-based diseases, such as the modification of tetanospasmin toxin of tetanus to remove its toxic effect but retain its immunogenic effect.Smallpox was most likely the first disease people tried to prevent by inoculating themselves and was the first disease for which a vaccine was produced. The smallpox vaccine was discovered in 1796 by the British physician Edward Jenner, although at least six people had used the same principles years earlier. Louis Pasteur furthered the concept through his work in microbiology. The immunization was called vaccination because it was derived from a virus affecting cows (Latin: vacca—cow). Smallpox was a contagious and deadly disease, causing the deaths of 20–60% of infected adults and over 80% of infected children. When smallpox was finally eradicated in 1979, it had already killed an estimated 300–500 million people in the 20th century.In common speech, 'vaccination' and 'immunization' have a similar meaning. This distinguishes it from inoculation, which uses unweakened live pathogens, although in common usage either can refer to an immunization. Vaccination efforts have been met with some controversy on scientific, ethical, political, medical safety, and religious grounds. In rare cases, vaccinations can injure people and, in the United States, they may receive compensation for those injuries under the National Vaccine Injury Compensation Program. Early success and compulsion brought widespread acceptance, and mass vaccination campaigns have greatly reduced the incidence of many diseases in numerous geographic regions.
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