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SAG-2 oral  rabies vaccine A. J.  BARRAT
SAG-2 oral rabies vaccine A. J. BARRAT

... The innocuity for cats and dogs at dosages that are 10 times greater than that designated for field application was shown to be complete. The short-term innocuity for the red fox of a dose greater than that intended for use in the field was confirmed. Taking these and results obtained in about 20 sp ...
The Lymphatic System
The Lymphatic System

... are killed off before they reach maturity. If those cells did reach maturity and enter the blood stream, our lymphatic system would attack some of our own cells. It is believed this is how multiple sclerosis works, for example. Antigens tend to be big, but sometimes small molecules, called haptens, ...
ENDOVAC-Bovi® in Lactating Dairy in Cows
ENDOVAC-Bovi® in Lactating Dairy in Cows

... Traditionally, treatment of coliform mastitis has been initiated only after the development of clinical illness. Therapy has been met with varying success. The chief disadvantage of treatment initiated after clinical illness has developed is that the disease has frequently advanced to an irreversibl ...
Dr. JL Jarry
Dr. JL Jarry

... Have antigen specific receptors on their surface Antigen binds with receptor This stimulates the B-cell to undergo clonal expansion B-cells divide into plasma cells Plasma cells mass-produce antibodies Antibodies circulate, find antigens, bind to them, and mark them for latter destruction • The dest ...
Chapter 17 Genetics of Immunity
Chapter 17 Genetics of Immunity

... B. the heart and blood vessels and the blood cells within the vessels. C. about 2 trillion cells, their secretions, and the organs where they are produced and stored. D. all of the bacteria and viruses that are normally present in our bodies plus our blood cells. 2. An antigen is A. a molecule that ...
Chapter 17 Genetics of Immunity
Chapter 17 Genetics of Immunity

... B. the heart and blood vessels and the blood cells within the vessels. C. about 2 trillion cells, their secretions, and the organs where they are produced and stored. D. all of the bacteria and viruses that are normally present in our bodies plus our blood cells. 2. An antigen is A. a molecule that ...
Autoimmune diseases
Autoimmune diseases

...  Auto Immunity (auto allergy)  Immune response of auto Ab against self Ag  Humoral or cell mediated immune response against the constitute’s of the body’s own tissues.  There are more than 80 different kinds of diseases caused by autoimmunity. Autoimmune diseases is a group of disorders in which ...
Chapter 1 – Testbank Multiple Choice Questions
Chapter 1 – Testbank Multiple Choice Questions

... a. Is about 30 minutes b. Is about 60 minutes c. Is about 90 minutes d. Varies with each procedure Answer: d 12. Optimal pH has not been determined for immunohematologic testing, but it is generally believed that testing should be performed within what pH range? a. 4.2–5.8 b. 5.8–7.5 c. 6.8–7.2 d. 7 ...
Advances in Immunotherapy: Abhijit Guha Award Presentation
Advances in Immunotherapy: Abhijit Guha Award Presentation

... we would have a tremendous amount of toxicity, because targeting those proteins would lead to autoimmunity. As we have progressed in the field of immunotherapy, every time we have tried to target normal proteins, and we have done that successfully, it has led to autoimmunity, sometimes life-threaten ...
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... [Compound] (M) PEPTIMMUNE CONFIDENTIAL ...
phoPlphoQ-Deleted Salmonella typhi (Ty800) Is a Safe and
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... of 2 or 3 subjects receivedsingle oral doses of 107, 108, 109, or 1010 cfu. Two volunteers who received the largest dose had self-limited side effects; no bacteremias were detected. Ten of 11 subjects had evidence of intestinal immune responses to the vaccine as measured by increases in S. typhi lip ...
Faculty of Infectious and Tropical Diseases
Faculty of Infectious and Tropical Diseases

... Department of Immunology and Infection (Head: Professor Eleanor Riley) Research in the Department of Immunology and Infection centres on analysis of the host response to infection at the molecular, cellular and population levels. The goals are to develop a greater understanding of basic mechanisms o ...
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... • In addition, it has an extraordinary capacity to distinguish between different, even closely related, microbes and molecules, and for this reason it is also called specific immunity ...
millhouse integrative medical centre newsletter february march 2012
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... Flu vaccines have weaker versions or parts of the actual virus in them. These ‘parts’ are known as antigens which are like the virus’ finger prints. They are not strong enough to cause illness (most of the time) but are strong enough to activate an immune response. When a foreign body (bacteria or v ...
Lecture-6-ANTIBODY-STRUCTURE-AND
Lecture-6-ANTIBODY-STRUCTURE-AND

... ANTIBODY STRUCTURE An antibody consists of four polypeptides: two identical light chains and two identical heavy chains form a Y-shaped molecule. Each light chain is connected to a heavy chain by a disulfide bond and the two heavy chains are connected by two disulfide bonds. Antigen binding and eff ...
Slide 1
Slide 1

... • In addition, it has an extraordinary capacity to distinguish between different, even closely related, microbes and molecules, and for this reason it is also called specific immunity ...
Immunity to Infection
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... • fatty acids toxic to most bacteria • epithelial surfaces – cleansed by ciliary action in the trachea or by flushing of the urea • pH changes in the stomach and vagina (acid) • commensals in the vagina, the epithelium secretes glycogen, which is metabolized by particular species of commensal ...
Immunopathological reactions type III
Immunopathological reactions type III

... • transfer of small doses of fetal antigens in maternal circulation causes tolerance ... ...
Lymphatic System Part 2
Lymphatic System Part 2

... Adaptive Defense System: Third Line of Defense  Self-antigens  Human cells have many surface proteins  Our immune cells do not attack our own proteins  Our cells in another person’s body can trigger an immune ...
Targeted Genetics Corporation - Morningstar Document Research
Targeted Genetics Corporation - Morningstar Document Research

... Vaccine Initiative (IAVI), which is focused on developing an AAV-based vaccine for use in developing nations. We believe that a safe and effective vaccine against HIV is the best way to slow the growth of the AIDS pandemic. The focus of the program funded by this contract is to develop an AAV-based ...
Microbiology – Chapter 15
Microbiology – Chapter 15

... 6. Small molecules that are too small to cause an immune response are called haptens. Penicillin is an example. By itself, too small to be antigenic, but it combines with serum proteins and then can become antigenic (penicillin allergy ) ...
Everyday our bodies are under attack. While invisible to the naked
Everyday our bodies are under attack. While invisible to the naked

... and remember that viral “bad guy” in the future. This “immune memory” is a hallmark of the immune system that enables it to wipe out that same virus with great speed, if seen again. A vaccine’s purpose is to create immune memory, conferring protection without an individual ever having to be infected ...
200607b_NTU-EN101
200607b_NTU-EN101

... Produced by a recombinant Chinese Hamster Ovary (CHO) cell and/or recombinant yeast The inflammation associated with hepatitis A virus and with hepatitis B virus can be prevented Useful for administration to children who dislike having ...
Immune Response 1. Cells involved in the Immune response #1. B
Immune Response 1. Cells involved in the Immune response #1. B

... 13. Major divisions of the immune response. Cell-mediated Response: One main mechanism of the immune system. It involves lymphocytes working alone (usually T lymphocytes) or is assisted by macrophages. Cellmediated response regulates both major responses (humoral and cell-mediated). The two are int ...
IMT- II PG - E
IMT- II PG - E

... d. all of the above 6. Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto a. bentonite particles b. RBCs c. latex particles d. all of these 7. Commercially available ELISA kits are used for the detection of ______________ a. rotavirus b. hepatitis B s ...
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Immunocontraception

In the strictest sense immunocontraception is the use of an animal's immune system to prevent it from fertilizing offspring. More generally the field of immunocontraception includes related technologies that prevent embryonic implantation.Typically immunocontraception involves the administration of a vaccine that induces an adaptive immune response which causes an animal to become temporarily infertile. Contraceptive vaccines have been used in numerous settings for the control of wildlife populations. However, experts in the field believe that major innovations are required before immunocontraception can become a practical form of contraception for human beings.Thus far immunocontraception has focused on mammals exclusively. There are several targets in mammalian sexual reproduction for immune inhibition. They can be organized into three categories.Gamete production Organisms that undergo sexual reproduction must first produce gametes, cells which have half the typical number of chromosomes of the species. Often immunity that prevents gamete production also inhibits secondary sexual characteristics and so has effects similar to castration.Gamete function After gametes are produced in sexual reproduction, two gametes must combine during fertilization to form a zygote, which again has the full typical number of chromosomes of the species. Methods that target gamete function prevent this fertilization from occurring and are true contraceptives.Gamete outcome Shortly after fertilization a zygote develops into a multicellular embryo that in turn develops into a larger organism. In placental mammals this process of gestation occurs inside the reproductive system of the mother of the embryo. Immunity that targets gamete outcome induces abortion of an embryo while it is within its mother's reproductive system.↑ ↑ ↑ ↑ ↑ ↑ ↑
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