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VACCINES
VACCINES

...  Live nonpathogenic strains can carry antigenic determinants from pathogenic strains.  If the agent cannot be maintained in culture, genes of proteins for antigenic determinants can be cloned and expressed in an alternative host e.g. E. coli. ...
INFLUENZA VACCINE VACCINATION OF PRETERM INFANTS In
INFLUENZA VACCINE VACCINATION OF PRETERM INFANTS In

... Decreased seroconversion rates might occur among certain preterm infants with low birth weights (ie, less than 2,000 g) after administration of HepB vaccine at birth. However, by chronological age 1 month, all preterm infants, regardless of initial birth weight, are as likely to respond as adequatel ...
Immune System:
Immune System:

... tears, saliva, nasal secretions and sweat that lyses cells. c. histamine prostaglandins, complements and leukotriens that promote inflammation by attracting leukocytes and stimulating phagocytes. d. the other chemical mediator is pyrogens released by neurophils and monocytes that stimulate fever pro ...
Use of virus-like particles for therapeutic vaccination
Use of virus-like particles for therapeutic vaccination

... Introduction: Life cycle of Plasmodium falciparum ...
Chapter 10 Classification
Chapter 10 Classification

... • Strain (subspecies) – organisms within the species with slightly different characteristics. • E.coli O157:H7 – cattle • Transmitted in undercooked hamburgers • Bloody diarrhea (dysentery) ...
Protocol S1.
Protocol S1.

... adverse events (SAEs) and discontinuations due to adverse events will be described in detail. In addition, all data will be reported in subject listings. The results of antibody secreting cells (ASCs) will be given as ASC / 106 PBMC. These data are used to calculate geometric means ± SEM; the two gr ...
23. Frenkel lecture: FMD vaccine development - past and future
23. Frenkel lecture: FMD vaccine development - past and future

... However, the response of CD4 and CD8 T cells isolated from infected cattle are consistently low compared to the response to control antigens, despite the absence of generalised immunosuppression in the FMDV infected cattle. The specific CD4 response to vaccination is variable. MATERIAL AND METHODS B ...
Inactivated vaccines
Inactivated vaccines

...  Transfect plasmid vector into E.coli.  Grow in presence of antibiotic and analyse for expression of vaccine antigen  Isolate plasmid construct and electroporate into BCG.  Grow in presence of antibiotic and analyse for expression of antigen.  Immunise host with BCG. Can incorporate many genes ...
Blank Jeopardy
Blank Jeopardy

... but a second cell population remains free. ...
Immune System
Immune System

... B) REGARD C) MOTORS D) LEGAL ...
Next-generation DNA vaccine technology for allergy, infectious
Next-generation DNA vaccine technology for allergy, infectious

... the ability to directly stimulate MHC II antigen presentation or because they are administered to cells that lack MHC II altogether, such as muscle cells. LAMP vaccines have the potential to evoke an immune response comprising cellular immunity (cytotoxic T cells) as well as adaptive immunity (the h ...
Vaccines And Non-communicable diseases
Vaccines And Non-communicable diseases

...   Chronic hepatitis B virus infection is a major cause of liver cancer. In 2008, liver cancer killed 700,000 people, representing 9 % of all cancer deaths.   Human papillomavirus ( HPV ) causes virtually all cervical cancer cases. In 2008, 275,000 women died of cervical cancer ; 88 % of those deat ...
Слайд 1 - sechenov.ru
Слайд 1 - sechenov.ru

... Manifestations: ● peripheral blood T-cell levels are reduced; B-cell levels - normal ● paracortical areas of the lymph nodes, periarteriolar sheaths of the spleen are depleted ● serum immunoglobulin concentrations are frequently normal, but Ab responses, particularly of IgG and IgA isotypes, are imp ...
Screening Checklist for Contraindications to Vaccines for Children and
Screening Checklist for Contraindications to Vaccines for Children and

... or long-term high-dose steroid therapy has ended. For details and length of time to postpone, consult the ACIP statement.1 Some immune mediator and immune modulator drugs (especially the antitumor-necrosis factor agents adalimumab, infliximab, and etanercept) may be immunosuppressive. The use of liv ...
UNIT 7: Immunology and Vaccinology
UNIT 7: Immunology and Vaccinology

... an animal will produce resistance to that specific agent. The animal is protected on a subsequent exposure to the same organism. There are various types of vaccines. 1. Live vaccine: live vaccine usually contain a live micro organism which has been weakened (attenuated) in some way, or a naturally o ...
IN RESPONSE TO DAMAGE Innate, or nonspecific, immunity
IN RESPONSE TO DAMAGE Innate, or nonspecific, immunity

... During the humoral immune response, IgM is the first class of antibody made. After several days, other classes appear. Exactly which other Ig classes a B cell makes depends on the kind of interleukins it receives from the T helper cells. Antibodies can sometimes stop an antigen’s disease-causing ac ...
Humoral Immunity
Humoral Immunity

... then activates an appropriate B cell by releasing IL-2 to it. ...
Immune System Review Sheet
Immune System Review Sheet

... 5. Outline the steps of humoral immunity. Include the terms antibody, macrophage, T cell, B cell, helper T cells, plasma cells, memory cells. 6. Outline the steps of cell-mediated immunity. Include the terms macrophage, T cell, helper T cell, killer T cell, permanent immunity. 7. Why is it that most ...
I understand that due to my occupational exposure to blood... materials, I may be at risk of acquiring hepatitis B...
I understand that due to my occupational exposure to blood... materials, I may be at risk of acquiring hepatitis B...

... Office of Risk Management and Environmental Health & Safety HEPATITIS B VACCINATION DECLINATION FORM ...
Immune System Notes
Immune System Notes

... material we cannot - Only if E.Coli are introduced in an unnatural manner can they break through the first line of defense and harm us ...
Trends in Research and development of new veterinary drug
Trends in Research and development of new veterinary drug

... Based on observations that the folate receptor (FR) is widely expressed in human cancer, researchers at Purdue University in the United States examined expression of FR in canine cancers and developed a FR-targeting form of DDS for vinblastine. One of the problems with this system is the development ...
Employee Immunization Exemption Form
Employee Immunization Exemption Form

... I understand that due to my occupational exposure to blood or other potentially infectious materials I may be at risk of acquiring Hepatitis B virus (HBV) infection. I have been given the opportunity to be vaccinated with hepatitis B vaccine, at no cost to myself. However, I decline hepatitis B vacc ...
2011 American Association of Swine Veterinarians
2011 American Association of Swine Veterinarians

... • Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more effective PRRS vaccines H.J. Nauwynck, et al. (ISU Swine Disease Conference, 2010) ...
RD Schultz Laboratory, School of Veterinary Medicine
RD Schultz Laboratory, School of Veterinary Medicine

... 2. What is the benefit of antibody testing? Why not just revaccinate? Antibody or titer testing is much safer than revaccinating an already immune animal. Although the potential for the vaccine to cause an adverse reaction is low, if the animal does not need the vaccine, this risk is completely unne ...
Complexity and the Immune System
Complexity and the Immune System

... • Genetic variation can lead to B and T cells that cover the entire range of pathogens, and each antibody hits on average one antigen • B cells differentiate into memory cells, which are able to quickly split into lots of effector cells and more memory cells • After an attack, have more memory cells ...
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Immunocontraception

In the strictest sense immunocontraception is the use of an animal's immune system to prevent it from fertilizing offspring. More generally the field of immunocontraception includes related technologies that prevent embryonic implantation.Typically immunocontraception involves the administration of a vaccine that induces an adaptive immune response which causes an animal to become temporarily infertile. Contraceptive vaccines have been used in numerous settings for the control of wildlife populations. However, experts in the field believe that major innovations are required before immunocontraception can become a practical form of contraception for human beings.Thus far immunocontraception has focused on mammals exclusively. There are several targets in mammalian sexual reproduction for immune inhibition. They can be organized into three categories.Gamete production Organisms that undergo sexual reproduction must first produce gametes, cells which have half the typical number of chromosomes of the species. Often immunity that prevents gamete production also inhibits secondary sexual characteristics and so has effects similar to castration.Gamete function After gametes are produced in sexual reproduction, two gametes must combine during fertilization to form a zygote, which again has the full typical number of chromosomes of the species. Methods that target gamete function prevent this fertilization from occurring and are true contraceptives.Gamete outcome Shortly after fertilization a zygote develops into a multicellular embryo that in turn develops into a larger organism. In placental mammals this process of gestation occurs inside the reproductive system of the mother of the embryo. Immunity that targets gamete outcome induces abortion of an embryo while it is within its mother's reproductive system.↑ ↑ ↑ ↑ ↑ ↑ ↑
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