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Inhaled corticosteroids in COPD What are we really doing?
Inhaled corticosteroids in COPD What are we really doing?

...  Is benefit preserved with lower doses? ...
Understanding alcoholic liver disease - addiction
Understanding alcoholic liver disease - addiction

... abstinence from drinking before they will carry out liver transplantation. For severe life threatening acute on chronic liver cell failure, some centres will waiver this condition. Anecdotal reports from transplant centres have found a significant proportion of patients with end stage liver disease ...
Peripheral Vascular Disease - Calgary Emergency Medicine
Peripheral Vascular Disease - Calgary Emergency Medicine

... Acute Arterial Occlusion • Management – Medical • Anticoagulation -- IV heparin – should be started in ED – no studies have established any benefits with certainty – relative contraindications; recent neurosurgery (<6weeks), majore surgery <48hours ago, childbirth within <24hours, thrombocytopenia, ...
Support supplied by Parkinson's disease specialist nurses to Parkinson's disease patients
Support supplied by Parkinson's disease specialist nurses to Parkinson's disease patients

... individual emerged from the interviews and highlights the importance of the PD specialist nurse’s work for PD patients and their spouses. In order to support PD patients and their spouses, the PD specialist nurse should have extensive factual knowledge of PD. In-depth knowledge of the disease’s prog ...
Statistics Guide for Research Grant Applicants
Statistics Guide for Research Grant Applicants

... Development Support Units (RDSU) in the Region and detailed guidance notes accompanied the application form, a number of common statistical problems consistently emerged. It is hoped that in summarising these statistical weak points the handbook will be of use to those applying for research funding ...
Question 1
Question 1

... Choice 5: Tell the patient that it is crucial to take the medication because if he does not he could possible suffer a heart attack or stroke Score : 0 Choice Feedback: ...
Biomedical Interventional Protocol Template
Biomedical Interventional Protocol Template

... labeled. Complete Supplement A, if applicable. If the study involves radiation (e.g. mammograms, bone density measurements, cancer treatments) be sure to provide assurance that the appropriate institution’s ...
APIC State-of-the-art Report: The role of the infection preventionist in
APIC State-of-the-art Report: The role of the infection preventionist in

... RESULTS In total, 34 relevant sources were identified from the peer-reviewed literature and Internet search. Many authors described the infectious disease impact of mass casualty incidents and infection prevention interventions that will be required for an effective disaster response but did not spe ...
A RETROSPECTIVE COHORT ANALYSIS OF ANTIRETROVIRAL TREATMENT MODIFICATIONS
A RETROSPECTIVE COHORT ANALYSIS OF ANTIRETROVIRAL TREATMENT MODIFICATIONS

... prognosis of patients starting HAART. In a clinical setting where drug options are very limited, it is also important to understand conditions that may lead to any modifications (modifications can either be a single drug substitution or a regimen switch) to a HAART regime and the risk factors that m ...
Kidney Disease - Kidney Foundation of Northwest Ohio
Kidney Disease - Kidney Foundation of Northwest Ohio

... In a perfect world, every person is born with, and keeps, (how many?) healthy, functioning kidneys. ...
Diagnostic assessment of patients with interstitial lung disease REVIEW
Diagnostic assessment of patients with interstitial lung disease REVIEW

... oh at ib ory ite S d o ...
Guide Materials for ASPECT-R Tool
Guide Materials for ASPECT-R Tool

... 0 = Specific, protocol-mandated selection criteria for the eligible study population or non-random site selection restrict confident generalization of study results to 10% or less of the hypothesisdefined population of interest. 1 = Specific, protocol-mandated selection criteria for the eligible stu ...
Myozyme : EPAR - Scientific Discussion
Myozyme : EPAR - Scientific Discussion

... levels of glycogen in various tissues, particularly cardiac and skeletal muscle, as well as respiratory muscles, leading to generalised myopathy, cardiomyopathy and respiratory failure. Pompe disease can be considered as a spectrum of disease as the clinical presentation of GAA deficiency ranges fro ...
The need for cardioversion - Calgary Emergency Medicine
The need for cardioversion - Calgary Emergency Medicine

... Not all patients need cardioversion Defined role for attempting cardioversion When there is doubt about thrombo-embolic risk, cardioversion should be deferred Anticoagulation recommendations reduce the burden of ischemic stroke ...
Parkinson`s Update Newsletter
Parkinson`s Update Newsletter

... problems develop. It is hypothesized that isradipine will preserve dopamine levels over an extended period of time, thereby slowing the progression of PD. “If it proves to be safe and effective, this drug will change the way we treat Parkinson’s disease,” says Simuni, who is the principal study inve ...
Sphingolipids and lysosomal pathologies - Limes-Institut-Bonn
Sphingolipids and lysosomal pathologies - Limes-Institut-Bonn

... have been studied in genetically manipulated mice, where they cause a broad spectrum of pathological phenotypes [27,28]. In human patients only 3 diseases, have been described so far [29–32]. Deficiency of ganglioside GM3 synthase causes an infantile onset refractory epilepsy [29] or a complex heredi ...
Peyronies disease
Peyronies disease

... penile prostheses. For example, patients with penile deformity combined with vasculogenic erectile dysfunction are best treated by implantation of penile prosthesis. ...
to the full program book with all educational
to the full program book with all educational

... Exhibitor Drawing- A door prize drawing card can be found in your meeting packet. In order to qualify for the drawing, you must have an exhibitor from each company on your card sign or initial the appropriate space on the card. After completing your card, sign it and return it to the registration de ...
alzheimer`s disease
alzheimer`s disease

... has developed Alzheimer’s disease, your risk will be higher, but genetics seems to account for only a small part of all cases. There are probably many causes for Alzheimer’s disease, and factors such as obesity, advanced age, high blood pressure, and metabolic problems could possibly contribute to t ...
I. Incidental Findings in Magnetic Resonance Imaging
I. Incidental Findings in Magnetic Resonance Imaging

... is the finding of an occult venous malformation deep in the brain that carries a small risk of hemorrhage but for which no therapy is available. A third category includes findings of no health consequence for which disclosure is not required, though if a subject was interested in the findings there ...
Methodological issues in therapeutic trials of COPD PERSPECTIVE
Methodological issues in therapeutic trials of COPD PERSPECTIVE

... apparent effectiveness of inhaled corticosteroids (ICS) in reducing exacerbation rates, but not so for mortality. In the present article, the authors review methodological issues in the TORCH and previous trials, such as patients already receiving ICS before randomisation and the absence of follow-u ...
alzheimer`s disease
alzheimer`s disease

... has developed Alzheimer’s disease, your risk will be higher, but genetics seems to account for only a small part of all cases. There are probably many causes for Alzheimer’s disease, and factors such as obesity, advanced age, high blood pressure, and metabolic problems could possibly contribute to t ...
Primary gastric lymphoma in a soldier presenting as acute
Primary gastric lymphoma in a soldier presenting as acute

... The initial symptoms of upper abdominal pain and early satiety may be vague and nonspecific. Other common symptoms include weight loss, nausea, vomiting, abdominal fullness and indigestion. Symptoms and signs may mimic those of other abdominal pathologies which are prevalent among young adults, incl ...
British Society for Paediatric Gastroenterology and
British Society for Paediatric Gastroenterology and

... Approximately 1/3 of childhood IBD is ulcerative colitis. Misdiagnosis is also a problem. The main error had been to commence treatment without a tissue diagnosis of chronic inflammatory bowel disease. Expert surgical services are essential as many children come to surgery (22). Timing is particular ...
Communicable Disease Control Manual
Communicable Disease Control Manual

... Antiviral treatment is indicated for some chronic hepatitis B carriers but this would be determined in consultation with an Infectious Disease Specialist. Exclusion Not applicable. Standard precautions/routine practices measures apply. Physicians are required to report infection to College of Physic ...
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Epidemiology



Epidemiology is the study of the patterns, causes, and effects of health and disease conditions in defined populations. It is the cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, and interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences.Major areas of epidemiological study include disease etiology, transmission, outbreak investigation, disease surveillance and screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. Epidemiologists rely on other scientific disciplines like biology to better understand disease processes, statistics to make efficient use of the data and draw appropriate conclusions, social sciences to understand proximate and distal causes better, and engineering for exposure assessment.
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