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Vaccines for the 21st century
Vaccines for the 21st century

... recombinant protein antigens that form a non-infectious viral-like particle (VLP). In the last decade, progress in genomics has also contributed to vaccine development. Unlike the other meningococci, Neisseria meningitidis type B (MenB) is covered by a capsular polysaccharide that is similar to poly ...
A guide to vaccinations at three years and four months of age
A guide to vaccinations at three years and four months of age

... Do these vaccines contain thiomersal? No. These pre-school vaccines do not contain thiomersal. Thiomersal is a mercury-based preservative (see the glossary on page 28). We don’t hear about most of these diseases any more, so are these immunisations really necessary? Since immunisation was introduce ...
BVGH - Who We Are - BIO Ventures for Global Health
BVGH - Who We Are - BIO Ventures for Global Health

... expressing VP7 (glycoprotein, G) and VP4 (protease-sensitive protein, P) from human rotaviruses. 2. Rotarix, developed by GlaxoSmithKline: Contains a single strain of rotavirus, which is derived from a human isolate and was attenuated by multiple passages in cell culture. Both vaccines are administe ...
Jumpstarting Infectious Disease Research With
Jumpstarting Infectious Disease Research With

... virulence and host-pathogen interactions. These approaches have led to some encouraging results. Hung and her collaborators designed a high-throughput imaging assay and chemical screen to look for small molecules that act in the infected macrophages and limit tuberculosis bacterial growth by interfe ...
SKC667 STL v10n1_2.indd
SKC667 STL v10n1_2.indd

... twice-daily course for episodic management of recurrent herpes.5 Suppressive therapy is preferred when recurrences are frequent, severe, and/or emotionally disturbing. An open-label study demonstrated the preference of suppressive therapy with valacyclovir as once-daily therapy over the episodic do ...
New Developments in Vaccine Safety Monitoring Canada and the
New Developments in Vaccine Safety Monitoring Canada and the

... General definition: Any untoward medical occurrence which follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The AE may be any unfavourable or ...
Your Hosts for Peds-Jeopardy Peds-Jeopardy
Your Hosts for Peds-Jeopardy Peds-Jeopardy

... • There are increasing numbers of children not being vaccinated, which will affect the herd immunity. • Also there are increases in imported cases (e.g, France, Switzerland) • 5% of the population is not immune after one MMR vaccine, soa second dose is given at ages 4- 6 year ...
New Drug Update
New Drug Update

...  The available evidence does not support the use of betablockers as first-line drugs in the treatment of hypertension. ...
10.5mb ppt
10.5mb ppt

... “Nothing in biology makes sense except in the light of evolution” ---Theodore Dobzhansky ...
Low DNA HTLV-2 proviral load among women in S˜ao Paulo City
Low DNA HTLV-2 proviral load among women in S˜ao Paulo City

... (16–123 copies/104 ). HCV co-infection is highly prevalent among HTLV-2-infected subjects, probably due to the similar transmission route (Toro et al., 2005]. It might be that the presence of other viral co-morbidities could also influence the HTLV-2 replication rate. Further studies have been propo ...
B. Pharm - South African Pharmacist`s Assistant
B. Pharm - South African Pharmacist`s Assistant

... The immune system is the body’s defence system against any foreign particle that enters the body, be it a virus, a bacterium or, in allergic people, dust or pollen. Our bodies are bombarded by foreign particles all the time and people who seem to get one illness after the next could benefit from tak ...
Case # 2 - American Academy of Pediatrics
Case # 2 - American Academy of Pediatrics

... All rotavirus vaccines are oral, live attenuated, containing glycoprotein (VP7) and protease-cleaved proteins (VP4) of Group A rotavirus, the most prevalent type found in humans. ROTASHIELD –licensed in 1998, tetravalent rhesushuman reassortment, withdrawn from the market due to cases of intussuscep ...
Oral Surgery And Oral Infections
Oral Surgery And Oral Infections

... mouth is disturbed, favoring candida over the other microorganisms of the oral cavity. This disturbance of the oral cavity can be caused by a number of factors such as, taking antibiotics, or chemotherapy. Systemic problems can also cause an imbalance; diabetes, malnutrition, drug abuse, or immune d ...
Clinical Trial
Clinical Trial

... The medical or social standards determining whether a person may or may not be allowed to enter a clinical trial. These criteria are based on such factors as age, gender, the type and stage of a disease, previous treatment history, and other medical conditions. It is important to note that inclusion ...
March 4, 2016 Bibliography
March 4, 2016 Bibliography

... Foged C. Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We? Curr Pharm Des. 2016 Feb 2. [Epub ahead of print] Folayan MO, Peterson K, Kombe F. Ethics, emergencies and Ebola clinical trials: the role of governments and communities in offshored research. Pan Afr Med. 2015 Oct 10;2 ...
Protection of chicken against very virulent IBDV provided by in ovo
Protection of chicken against very virulent IBDV provided by in ovo

... has been used to prevent IBD. These live conventional vaccines can cause immunosuppression and some bursal atrophy, and may not fully protect chickens against the very virulent IBDV (vvIBDV) strain and antigenic variants of IBDV [34,38]. Several DNA vaccines containing the VP2 or VP2-VP4-VP3 genes h ...
October 2014 website final
October 2014 website final

... of porcine (pig) FVIII, used because it is similar enough to human FVIII to be effective in blood clotting, but less likely to be affected by the antibodies against human FVIII that are present in people with acquired hemophilia A. b) The FDA has received the investigational new drug (IND) applicati ...
as PDF
as PDF

... In 1796, Edward Jenner first used the term, “vaccination,” to describe his studies which used poxvirus derived from lesions in cows to protect humans against infection with smallpox (Barquet & Domingo, 1997). Later, Louis Pasteur demonstrated that animals and people could be protected against diseas ...
COMMITTEE ON INFECTIOUS DISEASES ; originally published online September 2, 2013; Pediatrics
COMMITTEE ON INFECTIOUS DISEASES ; originally published online September 2, 2013; Pediatrics

... of an effective immunization strategy. Giving the vaccine promptly and early during the influenza season is not felt to pose a significant risk that immunity might wane before the end of the season. The seasonal vaccine is not perfect, but it still is the best strategy available for preventing illness ...
WHO information sheet - World Health Organization
WHO information sheet - World Health Organization

... AD et al., 2000, Ascherio A et al., 2001,Touze et al., 2002, De Stefano et al., 2003) including a re-analysis using a new design that compares cases only (Hocine et al., 2007). However, these findings have also been challenged. In a nested case-control study within the General Practice Research Data ...
Immunity and Vaccinations
Immunity and Vaccinations

... stay in an individual’s immune system for a lifetime. This protects a person from getting sick again. This protection is called immunity. B. Vaccines 1. Live organisms – must be non-virulent for humans, or treated in the lab to weaken them so they are not as pathogenic to humans. 2. Attenuated – an ...
Herpes Brainstem Encephalitis: A Cause of Intractable Emesis
Herpes Brainstem Encephalitis: A Cause of Intractable Emesis

... 1 to 5 second intervals. These discharges usually are seen over the temporal areas. Although there are no CSF characteristics that are considered pathognomonic, the fluid is abnormal in most cases. CSF examination often reveals a lymphocytic pleocytosis of 5 to 500 cells/mm3, a slight to moderate el ...
Infectious Laryngotracheitis - Michigan State University Extension
Infectious Laryngotracheitis - Michigan State University Extension

... In some counties in Michigan, this disease has caused such a problem that they no longer have chickens at their fairs. This does not have to happen in your county if people would follow rules in consideration of other people’s chickens. Fairs could choose not to allow birds that have been vaccinated ...
Diagnosis
Diagnosis

...  double-stranded DNA virus in the Hepadnaviridae family.  The incubation period is 90 days from time of exposure to onset of symptoms, but may vary from 6 weeks to 6 months .  Acutely infected individuals develop clinically apparent hepatitis with loss of appetite, nausea, vomiting, fever, abdomi ...
October 2012 Monitoring International Trends
October 2012 Monitoring International Trends

... practice based on the results. AABB has categorized dengue as a high priority agent threatening transfusion recipient safety in the US. Dr Michael Busch, Director of Blood Systems Research Institute and Vice-President for Research and Scientific Affairs of Blood Systems, Inc., discussed in a recent ...
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Herpes simplex research

Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes.Examples of particular herpes research include, drug development and herpes vaccines.
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