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Bacterial Meningitis
Bacterial Meningitis

... •The vaccines against Hib are very safe and highly effective. By 6 months of age, every infant should receive at least three doses of a Hib vaccine. A fourth dose (booster) should be given to children between 12 and 18 months of age. •The vaccine against Neisseria meningitidis (meningococcal vaccine ...
MENINGITIS, VIRAL
MENINGITIS, VIRAL

... 1. Agent: Various viruses, many associated with other specific diseases, can cause meningitis. At least half of all cases have no demonstrable agent identified. In the US, most cases are caused by enteroviruses; other agents include arboviruses (especially West Nile Virus), measles, herpes simplex t ...
HIV/AIDS: Opportunities to Address Pharmaceutical
HIV/AIDS: Opportunities to Address Pharmaceutical

... against both the viral glycoproteins that interact with receptors and co-receptors on the host cell membrane. The co-receptors CCR5 and CXCR4, are likely targets for therapeutic advances.10 The design of post-entry inhibitors remains problematic; the more advanced inhibitors include agonists of the ...
Skin Diseases
Skin Diseases

... Herpes Zoster (shingles) • Reactivation of latent varicella zoster virus (same virus that causes chickenpox) • Clinical diagnosis:  Rash  Starts off as papules, then progress to a cluster or group of vesicles. Over 3-4 days they become more pustular. The rash crusts by 10 days. Heal in 2-4weeks  ...
Lesson 12, Part 7
Lesson 12, Part 7

... vaccine. The results were published in Pediatrics, a respectable medical journal. The results were completely ignored by the medical and pharmaceutical community. In 1976, Charles Manclark, an FDA scientist, remarked, “The DPT had one of the worst failure rates of any product submitted to the Divisi ...
39. RNA Enveloped Viruses
39. RNA Enveloped Viruses

... called NS 1 encoded by the genome RNA of influenza virus. NS 1 has several functions, but the one pertinent to virulence is its ability to inhibit the production of interferon mRNA. As a result, innate defenses are reduced and viral virulence is correspondingly enhanced. Many species of animals (e.g ...
Kathleen Harriman, PhD, MPH, RN - California Immunization Coalition
Kathleen Harriman, PhD, MPH, RN - California Immunization Coalition

... the Secretary of the Department of Health and Human Services on the most effective means to prevent vaccine-preventable diseases in the civilian population  Vaccines and related agents (e.g., antisera, immune globulins, antivirals)  FDA-licensed vaccines (and unlicensed vaccines if warranted) ...
Clinical Case Management Guidelines of Ebola Virus Disease (EVD
Clinical Case Management Guidelines of Ebola Virus Disease (EVD

... 1. Nucleoside analogue inhibitors of the cell-encoded enzyme Sadenosylhomocysteine hydrolase (SAH) have been shown to inhibit Zaire ebolavirus replication in adult BALB/c mice infected with mouse-adapted Ebola virus. Inhibition of SAH indirectly inhibits transmethylation reactions required for viral ...
EXAMPLE 10/08: Intended as an example only
EXAMPLE 10/08: Intended as an example only

...  For local reactions recommend continuing cold compresses for 8-12 hours as needed and to seek medical care immediately if symptoms worsen or signs of systemic reaction occur.  Flag the patient’s record to indicate the allergy and record the reaction  Complete an Incident Report form per agency p ...
Herpes Simplex Keratitis Following Excimer Laser Application
Herpes Simplex Keratitis Following Excimer Laser Application

... Many people without clinical herpes simplex infection have latent virus. Worldwide, 60% to 90% of the adult population is positive for HSV-1 antibody and only 1% to 6% of primary infections are clinically recognized.8 Asymptomatic people can shed herpes simplex virus in tears.8 This report suggests ...
View US Prescribing Information - PDF Version
View US Prescribing Information - PDF Version

... of clinical significance in subjects with normal renal function. Therefore, no dosage adjustment is recommended when VALTREX is coadministered with digoxin, antacids, thiazide diuretics, cimetidine, or probenecid in subjects with normal renal function. Clinical Trials: Herpes Zoster Infections: Two ...
Varicella-Zoster Virus
Varicella-Zoster Virus

... Infections in HIV-Infected Adults and Adolescents ...
Is It herpes OR aphthous - Home
Is It herpes OR aphthous - Home

... a break in the mucous membrane integrity, although there is evidence that it may penetrate intact skin. In either case, transmission results from mucocutaneous contact with infected secretions and aerosols. When reactivated, the virus travels along the nerve axon to the surface epithelial cells and ...
Hemorrhagic Fevers - Columbia University
Hemorrhagic Fevers - Columbia University

... • Essentially supportive and directed toward ensuring adequate tissue delivery of oxygen, nutritional support, and hydration. • Hemorrhage is managed by replacement of blood, platelets, and clotting factors • Passive transfer of human antibodies has remained inconclusive in its benefit to Marburg an ...
Curriculum Vitae - University of Maryland School of Medicine
Curriculum Vitae - University of Maryland School of Medicine

... Total Indirect Costs: $80,780 Role: Oversaw microbiology and molecular biology studies to develop a microwave accelerated metal-enhanced flurorescence-based assay to detect Salmonella in blood, stool and feces in collaboration with Professor Chris D. Geddes at UMBC. ...
Case Scenario Conf DRAFT for CME
Case Scenario Conf DRAFT for CME

... Treated her with a 7d methylprednisolone taper with quick resolution of the stomatitis, adenitis, and fever ...
Mumps FAQs
Mumps FAQs

... Q: What is the current mumps situation in Ireland? A: Since early November 2004 there has been an increase in mumps cases among teenagers and young adults. This is more than double the number reported for the first 10 months of 2004. The cases appear to be occurring mainly in individuals who were ne ...
Overview of Drug Development
Overview of Drug Development

... Definite dose range finding study in patients with efficacy as primary endpoint. Exceptionally, Phase II studies can be used as pivotal trials, if the drug is intended to treat life-threatening or severely-debilitating illnesses as in oncology indications ...
Shingles (Herpes Zoster)
Shingles (Herpes Zoster)

... -The risk of spreading shingles is low if the rash is covered. People with shingles should keep the rash covered, not touch or scratch the rash, and wash their hands often to prevent the spread of VZV. -Shingles vaccine was recently recommended by the Advisory Committee on Immunization Practices (AC ...
Differentiating Kawasaki Syndrome From Microbial Infection
Differentiating Kawasaki Syndrome From Microbial Infection

... fronted with a child in whom KS is suspected. KS should be considered in any child with fever for more than 5 days, especially if the child has a rash and nonpurulent conjunctivitis. The differential diagnosis of KS is extensive and includes bacterial and viral infections and rheumatological disease ...
Massachusetts Department of Public Health (MDPH)
Massachusetts Department of Public Health (MDPH)

... ILI is defined as fever > 100o F with cough and/or sore throat, in the absence of a known cause. 1. MDPH epidemiologists can facilitate testing and provide control recommendations in the event of an outbreak. To prevent the transmission of all respiratory infections, including flu, implement the inf ...
2. What happens during a clinical trial?
2. What happens during a clinical trial?

... For the most part, yes. However, sometimes clinical trials are for experimental medications intended for very sick people, so in those cases there are generally more risks involved. The patient will always be advised of the risks involved. Clinical trials are governed by clearly defined internationa ...
What is it? What causes it? Who gets it? What are the symptoms
What is it? What causes it? Who gets it? What are the symptoms

... the skin rash or throat of the ill person. Once the virus is breathed in, illness begins about 2 weeks later. 90% of patients having this highly contagious disease are under 10 years of age with most between 5 - 9 years of age. Over 90% of family members also become infected if they have not been pr ...
Pertussis: Questions and Answers
Pertussis: Questions and Answers

... reported. With the introduction of a vaccine in the late 1940s, the number of reported pertussis cases in the U.S. declined from approximately 200,000 a year in the pre-vaccine era to a low of 1,010 cases in 1976. Since the 1980s, the number of cases of pertussis has increased, especially among babi ...
Management of Epithelial Herpetic Keratitis
Management of Epithelial Herpetic Keratitis

... ophthalmology at Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA. ...
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Herpes simplex research

Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes.Examples of particular herpes research include, drug development and herpes vaccines.
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