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Occupational Exposure
Occupational Exposure

... The main arguments in favour of two-drug PEP (fewer side effects, better adherence and course completion rates) are being addressed through switching to better-tolerated agents with lower pill burdens. At the same time, a potent three-drug PEP regimen is preferred because resistance to antiretrovira ...
Exam 1 Review Questions
Exam 1 Review Questions

... 5. How does population immunity impact the spread of a virus? 6. Be able to discuss the factors involved in disease outbreak and transmission from the class summaries of their assigned readings (see summaries below). Focus particularly on those things that all of the papers have in common, as well a ...
STI/HIV
STI/HIV

... • You can’t get an STI if your partner is a virgin ...
Virus and Viral Component Isolation
Virus and Viral Component Isolation

... reagent should be kept sealed and stored at 4C. Do not freeze. Viraffinity retains full activity when stored accordingly for approximately 1 year. ...
Viral Hemorrhagic fever
Viral Hemorrhagic fever

... -These are round, pleomorphic, and enveloped with a diameter of 120 nm. - Nucleocapsid with two single-stranded RNA circular segments. ...
the virus infection cycle
the virus infection cycle

... capitalized and the terms are printed in italics  Species designations are not capitalized (unless they are derived from a place name or a host family or genus name), nor are they italicized  The name of the taxon should precede the term for the taxonomic unit ; for example: ..."the family Paramyx ...
advice and facts about sexually transmitted infections
advice and facts about sexually transmitted infections

... and other bodily fluids that may contain viruses. If you currently have another sexually transmitted infection, you are more likely to contract HIV if you have unprotected sex with a partner that has HIV. If you know that you have been subjected to HIV within the last day or couple of days, you must ...
Slide 1
Slide 1

... HIV infection was estimated to occur midway between the last HIV negative test result and the first HIV positive test result HIV incidence density was calculated by dividing the number of events of HIV seroconversion by the number of person years of follow up Follow-up time for each FSW was calculat ...
Subclinical infection
Subclinical infection

... •Factors –Viral antigenecity is single or steady –Viramia –Variation of virus surface Ags. ...
HIV Transmission Serbia
HIV Transmission Serbia

... • Has a 5 year old child with this partner • They live with Lydia’s mother ...
In search of a Broad-spectrum anti
In search of a Broad-spectrum anti

... THE PROBLEM: Essentially there is a lack of treatment options for viral threats, especially should a new, hitherto unknown virus become prominent. Vaccines take substantial time to develop, and most anti-viral agents are highly specific to only one virus and in targeting viral proteins place strong ...
Viruses and Public Health
Viruses and Public Health

... though they aren’t cells, they still need a genetic blueprint so they can reproduce.  Viruses may have ds DNA, ss DNA, ds RNA, or ssRNA, depending on the virus. ...
chronic infections
chronic infections

... associated with activation of the C5b-C9 membrane attack complex and probably mediated by calcium entry; it is possible that the macrophage cytokine tumor necrosis factor (TNF) also participates in myelin damage. B, B cell; MHC II, class II major histocompatibility complex molecule; TCR, T cell rece ...
DNA viruses: Adeno-, Pox-Papilloma
DNA viruses: Adeno-, Pox-Papilloma

... • Describe diagnostic approaches • Understand the principles of prevention and treatment ...
Size and Shape of Viruses
Size and Shape of Viruses

... A vaccine contains a killed or weakened part of a germ that is responsible for infection. Because the germ has been killed or weakened before it is used to make the vaccine, it can not make the person sick. When a person receives a vaccine, the body reacts by making protective substances called "ant ...
Nucleic Acids
Nucleic Acids

... The RNA molecules function both as mRNA for synthesis of viral proteins and as genomes for new virus particles released from the cell New HIV leaving a cell ...
Ch 19
Ch 19

... The RNA molecules function both as mRNA for synthesis of viral proteins and as genomes for new virus particles released from the cell New HIV leaving a cell ...
written text - FailingsOrigin persistence and Failings of HIV/AIDS
written text - FailingsOrigin persistence and Failings of HIV/AIDS

... Several years ago I reported that the cumulative record of HIV testing shows that what is being detected by those tests is not an infectious agent. Details are in 3 articles in JSE (19 #4, 20 #1, 2) and further details and discussion are in the 2007 book, The Origin, Persistence and Failings of HIV/ ...
Instrumentation and Process Control
Instrumentation and Process Control

... then serves as the template for the synthesis of the actual viral genome. The following examples from should make this clear: (1) poliovirus makes a negative-strand intermediate, which is the template for the positive-strand genome; (2) influenza, measles, and rabies viruses make a positive strand i ...
2016 VIRUS POWERPOINT
2016 VIRUS POWERPOINT

...  Some viral envelopes are derived from the host cell’s plasma membrane as the viral capsids exit  Other viral membranes form from host’s nuclear envelope and are then replaced by an envelope made from Golgi apparatus membrane. ...
A hepatitis C virus (HCV)
A hepatitis C virus (HCV)

... p≤0.05 are referred to as statistically significant and are indicated by an asterisk. In most experiments results are presented as means ± standard deviation. Student’s t-test for unpaired data, Fisher’s exact test or one-way ANOVA was used to test for significance as appropriate and indicated in th ...
Virus - Belle Vernon Area School District
Virus - Belle Vernon Area School District

... B. Viruses can have different relationships to their host cell. ...
Sexually Transmitted Infections
Sexually Transmitted Infections

... One out of 20 people in the United States will get infected with hepatitis B (HBV) some time during their lives. [9] Hepatitis B is 100 times more infectious than HIV. [10] Hepatitis A, hepatitis B and HPV are the only vaccinepreventable STDs/STIs. (Not all HPV types are covered by the vaccine, so w ...
peritoneal dialysis in hiv infected patients – a good option?
peritoneal dialysis in hiv infected patients – a good option?

... Kidney disease in human immunodeficiency virus (HIV) infected patients was firsty described in 19841. Since then, many other associations with this infection were observed. It is known that 5 to 10% of HIV infected patients will develop kidney dysfunction during the course of HIV disease2. However, ...
Online Viruses Activity
Online Viruses Activity

... Why does the DNA of the virus have to travel to the nucleus of the cell? ...
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HIV



The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through a number of mechanisms, including apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
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