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Conclusion Transmission electron microscopy Aim Materials
Conclusion Transmission electron microscopy Aim Materials

... growth reduction in MCF-7 and 78% in MCF-12A respectively (data not shown). In addition; findings also indicate that 2MeOE2bisMATE decreases cell growth in a time-and dose-depended manner. These spectrophotometrical results suggest that MCF-7 cells are more susceptible than MCF-12A cells. ...
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Cell Structure & Function
Cell Structure & Function

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Programmed cell death



Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. PCD is carried out in a regulated process, which usually confers advantage during an organism's life-cycle. For example, the differentiation of fingers and toes in a developing human embryo occurs because cells between the fingers apoptose; the result is that the digits are separate. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.Apoptosis and autophagy are both forms of programmed cell death, but necrosis is a non-physiological process that occurs as a result of infection or injury.Necrosis is the death of a cell caused by external factors such as trauma or infection and occurs in several different forms. Recently a form of programmed necrosis, called necroptosis, has been recognized as an alternate form of programmed cell death. It is hypothesized that necroptosis can serve as a cell-death backup to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors such as viruses or mutations.
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