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What is connectomics? - Brain Dynamics Laboratory
What is connectomics? - Brain Dynamics Laboratory

... allows the tracing and reconstruction of their cellular structure including long processes within a block of tissue. • While the labeling and tracing of all neurons in a complete mammalian brain may still represent an overly ambitious goal, more restricted components of a cellular connectome (for ex ...
Synaptic transmission
Synaptic transmission

... • Each time certain types of sensory signals pass through sequences of synapses, these synapses become more capable of transmitting the same type of signal the next time, a process called facilitation. • After the sensory signals have passed through the synapses a large number of times, the synapses ...
CaV3.1 is tremor rhythm pacemaker
CaV3.1 is tremor rhythm pacemaker

... and then propagated to cerebellar motor circuits, was inducible in wild-type mice but not in mice lacking the CaV3.1 gene in a pharmacological model of essential tremor induced by harmaline. The CaV3.1-deficient inferior olive neurons lacked subthreshold membrane potential oscillations and failed to ...
Rik Leeman assessment
Rik Leeman assessment

...  An assessment is a critical evaluation of information, for ...
Special Seminar Dynamic Control of Dentritic Excitability During Hippocampal Rhythmic Activity
Special Seminar Dynamic Control of Dentritic Excitability During Hippocampal Rhythmic Activity

... of the pyramidal neuron population and inhibit (DZNE) dendritic excitability. We find that interneurons of and Department of Epileptology, the CA1 hippocampal subfield can be separated University of Bonn Medical Center into two functional groups according to their theta Bonn, Germany response. The act ...
Brain
Brain

... and posture. ► Area involved in Parkinson’s disease. ...
Chapter 12: Central Nervous System
Chapter 12: Central Nervous System

... Basic Pattern of the Central Nervous System ...
HIPPOCAMPUS
HIPPOCAMPUS

... expressing basket, axo-axonic, bistratified and O-LM cells. The cells have differential temporal firing patterns during theta and ripple oscillations.The spike probability plots show that during different network oscillations representing two distinct brain states, interneurones of the same connecti ...
Chapter 2
Chapter 2

... • Provide support for the neurons to grow • Deliver nutrients to neurons • Produce myelin to coat axons ...
chapter two - Mr. Minervini ~ Human Behavior
chapter two - Mr. Minervini ~ Human Behavior

... 29. Katie has grown up sleeping with a fan running in her room since she was an infant. This provides white noise to drown out the television programs being watched by other family members who were still awake. In an effort to save electricity, her mother has started coming into her room and turning ...
Neuron highlight
Neuron highlight

... do the discrimination in a very brief time, what are these extended temporal codes used for? They could be used for representation of more specific odor features or even behavioral elements associated with the odorants, as it appears that mice do gain something with extra time. It has been shown tha ...
Data Supplement
Data Supplement

... the first session mice were sent across the ladder 3 times, then twice for the second training session, and only once for third and fourth training sessions. Baseline was obtained from the last training run. Post stroke testing was performed with one run per mouse. Ladder test performance was scored ...
Chapter 4
Chapter 4

... The amygdala appears to control emotional reactions, especially negative ones. In addition it provides energy for fighting and fleeing ...
Sparse coding in the primate cortex
Sparse coding in the primate cortex

... especially in infero-temporal cortex (IT). Cells’ preferences in IT are often difficult to account for by reference to simple stimulus features, such as orientation, motion, position, or color, and they appear to lie in the domain of shape (Gross, Rocha-Miranda, and Bender, 1972; Perrett et al., 198 ...
Treatment of Thalamic Pain by Chronic Motor Cortex Stimulation
Treatment of Thalamic Pain by Chronic Motor Cortex Stimulation

... on the burst hyperactivity 0/thaJamic neurons recorded in cats after deafferentiation of the spinotholamic pathway. Complete, long- term inhibifion of the burst fiyperacfivity was induced by slimuJation of the motor cortex. Based on this experimental finding, we treated seven cases of thalamic pain ...
מצגת של PowerPoint
מצגת של PowerPoint

... - The proportion of monocular, deprived-eye neurons, in deprived animals was no different to the proportion of these neurons in controls (supporting prediction ‘a’). - The entire deprived-eye response range of neurons responding predominantly or exclusively to the deprived eye (OD score 0–0.25) was ...
Paralys
Paralys

... The activity of neurotrophins makes them an ideal candidate for therapeutic applications. Since dying neurons in the brain cannot be replaced, treatment options for neurodegenerative diseases like Alzheimer's and Lou Gehrig's disease are limited. Recent studies suggest that these diseases act direct ...
Document
Document

... texture of objects (including, as we shall see, other people). (See Figure 6.34 .) ...
Slide 1
Slide 1

... • Novel behavior requires processing in several motor and parietal areas as it is continuously monitored for errors and then modified ...
Decision Making: Hitting an uncertain target | eLife
Decision Making: Hitting an uncertain target | eLife

... information supplied to the monkeys was high they tended to move the cursor to a location that was the average of the target locations in the previous trials: this approach makes sense when relatively little information is available. The Northwestern group also observed relatively high levels of act ...
Johsua Kani - How Genomic Analysis is Changing the Theory of Stress and Aging
Johsua Kani - How Genomic Analysis is Changing the Theory of Stress and Aging

... questionnaire also correlated with length and activity in the same fashion. Although this experiment did not directly test if glucocorticoids had an effect on telomere length, it would not be far-fetched to assume that relative glucocorticoid levels were elevated in proportion to perceived stress. T ...
Article on Rewiring the Brain
Article on Rewiring the Brain

... COULD THINKING ABOUT THOUGHTS IN A new way affect not only such pathological brain states as OCD and depression but also normal activity? To find out, neuroscientist Richard Davidson of the University of Wisconsin at Madison turned to Buddhist monks, the Olympic athletes of mental training. Some mon ...
English - Bernstein Center for Computational Neuroscience Berlin
English - Bernstein Center for Computational Neuroscience Berlin

... and extinction of fears. In the scientific journal PLoS Computational Biology, Ioannis Vlachos from the Bernstein Center Freiburg and colleagues propose for the first time an explanation for how fears that were seemingly overcome are actually only hidden. The reason for the persistency of fears is t ...
Photo Album
Photo Album

... Figure 19.7 Temporal coding of checkerboard-like stimuli called Walsh patterns by inferotemporal cortex neurons. (A) The top graph shows a spike density function and the bottom graph shows raster plots of individual spikes on each presentation. The horizontal line under each graph represents the st ...
Chapter 48 Nervous System
Chapter 48 Nervous System

... receptors clustered on the postsynaptic membrane. 5. Binding of neurotransmitters causes the protein receptors to change shape and open ion channels that initiate a depolarization wave in the postsynaptic neuron. 6. Neurotransmitters are quickly destroyed by enzymes or reabsorbed by the presynaptic ...
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