Formulation Considerations of Inhaled Products
... Formulation Considerations of Inhaled Products Inhalation Therapy Nebulizers and Formulations Dry Powder Inhalers and Formulations Metered Dose Inhalers (MDI) and Formulations Conclusions ...
... Formulation Considerations of Inhaled Products Inhalation Therapy Nebulizers and Formulations Dry Powder Inhalers and Formulations Metered Dose Inhalers (MDI) and Formulations Conclusions ...
Hypertension - National Medical Research Council
... Hypertension is a chronic disease that is a major risk factor for coronary artery disease, cardiac failure, stroke and renal failure, and is estimated to cause 4.5% of the current global disease burden. Hypertension is as prevalent in many developing countries, as in the developed world. In Singapor ...
... Hypertension is a chronic disease that is a major risk factor for coronary artery disease, cardiac failure, stroke and renal failure, and is estimated to cause 4.5% of the current global disease burden. Hypertension is as prevalent in many developing countries, as in the developed world. In Singapor ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... formulations are dumped in Indian market. If it continues so on ,pubic will suffer with drug induced health hazards in future. Accepted formulations are only 19.6%.we have to encourage these drugs for safety of patients. As these are cheaper than that of irrational and miscellaneous formulations ,th ...
... formulations are dumped in Indian market. If it continues so on ,pubic will suffer with drug induced health hazards in future. Accepted formulations are only 19.6%.we have to encourage these drugs for safety of patients. As these are cheaper than that of irrational and miscellaneous formulations ,th ...
UTILITY OF BROMOSUCCINIMIDE AS AN ENVIRONMENTAL-FRIENDLY REAGENT FOR SENSITIVE Innovare
... MS) [14, 15] and capillary electrophoresis [6] were also developed. However, these methods are expensive and not available at most quality control laboratories. The spectrophotometric technique continues to be the most preferred method for the assay of different ferent classes of drugs in pure, phar ...
... MS) [14, 15] and capillary electrophoresis [6] were also developed. However, these methods are expensive and not available at most quality control laboratories. The spectrophotometric technique continues to be the most preferred method for the assay of different ferent classes of drugs in pure, phar ...
Protocol Template Guidelines
... target disease, concomitant disease if required, etc.) Generally should include items such as: “subjects are capable of giving informed consent”, or if appropriate, “have an acceptable surrogate capable of giving consent on the subject’s behalf.” ...
... target disease, concomitant disease if required, etc.) Generally should include items such as: “subjects are capable of giving informed consent”, or if appropriate, “have an acceptable surrogate capable of giving consent on the subject’s behalf.” ...
Section II. Autonomic Drugs Chapter 6. Introduction to Autonomic
... occurred in 1989. Thus, 12 years had passed between project launch and approval for use in patients). In 1999, worldwide sales of omeprazole were $5.9 billion. By 2001, sales were $5.7 billion, and the worldwide market for ulcer drugs exceeded 14 billion. There are now five benzimidazole compounds a ...
... occurred in 1989. Thus, 12 years had passed between project launch and approval for use in patients). In 1999, worldwide sales of omeprazole were $5.9 billion. By 2001, sales were $5.7 billion, and the worldwide market for ulcer drugs exceeded 14 billion. There are now five benzimidazole compounds a ...
COMPARATIVE STUDY ON EFFECT OF DIFERENT TECHNIQUES USED IN THE FORMULATION OF FELODIPINE FAST DISSOLVING TABLETS
... antagonist compound (calcium channel blocker). Felodipine is practically insoluble in water and its dissolution rate is limited by its physicochemical properties. Felodipine fast dissolving tablets (FDT) have been prepared by direct compression method. Effect of method of preparation (i.e. solid ...
... antagonist compound (calcium channel blocker). Felodipine is practically insoluble in water and its dissolution rate is limited by its physicochemical properties. Felodipine fast dissolving tablets (FDT) have been prepared by direct compression method. Effect of method of preparation (i.e. solid ...
english, pdf
... The principle of the lyophilization technique is drying carried out at low temperature under conditions involving removal of water by sublimation (28). In this technique, the material is initially frozen below –18 °C and then reducing the pressure of the system and giving the necessary heat allows t ...
... The principle of the lyophilization technique is drying carried out at low temperature under conditions involving removal of water by sublimation (28). In this technique, the material is initially frozen below –18 °C and then reducing the pressure of the system and giving the necessary heat allows t ...
DEVELOPMENT AND VALIDATION OF A RAPID UV-SPECTROSCOPIC METHOD FOR THE
... and acetonitrile in the ratio of 50:50 v/v(used as diluent). The solution was sonicated for 15min and then the volume made up with a further quantity of diluent to give 20µg/mL. This solution was scanned against blank solution and extracted the spectrum Based on the spectrum a λmax of 260nm was sele ...
... and acetonitrile in the ratio of 50:50 v/v(used as diluent). The solution was sonicated for 15min and then the volume made up with a further quantity of diluent to give 20µg/mL. This solution was scanned against blank solution and extracted the spectrum Based on the spectrum a λmax of 260nm was sele ...
Curcuminoid drug interactions
... valuable in the prevention and treatment of many different degenerative diseases. As curcuminoids are often taken as supplements by some population groups, it may be asked whether this can lead to changes in the pharmacokinetics or pharmacodynamics of other drugs taken at the same time. It is partic ...
... valuable in the prevention and treatment of many different degenerative diseases. As curcuminoids are often taken as supplements by some population groups, it may be asked whether this can lead to changes in the pharmacokinetics or pharmacodynamics of other drugs taken at the same time. It is partic ...
literature review ii
... are the release retardant polymers such as HPMC K15M), HPMC E10 CR Prem., and Sodium Alginate and Independent variables are the percentage drug release at 1 h, percentage drug release at 8 h and hardness were studied. Box-Behnken response surface plots were drawn, statistical validity of the second ...
... are the release retardant polymers such as HPMC K15M), HPMC E10 CR Prem., and Sodium Alginate and Independent variables are the percentage drug release at 1 h, percentage drug release at 8 h and hardness were studied. Box-Behnken response surface plots were drawn, statistical validity of the second ...
International Editorial Board
... market; other drugs of this type include valsartan (launched in Germany), irbesartan (preregistration in Europe), and candesartan hexetil, eprosartan, telmisartan and tasosartan (all phase III). Losartan potassium is compared with enalapril in the Differential features table. ...
... market; other drugs of this type include valsartan (launched in Germany), irbesartan (preregistration in Europe), and candesartan hexetil, eprosartan, telmisartan and tasosartan (all phase III). Losartan potassium is compared with enalapril in the Differential features table. ...
Nitazoxanide (Alinia) - Texas Medicaid/CHIP Vendor Drug
... comparable efficacy to metronidazole in managing Clostridium difficile colitis, in both patients responsive and resistant to metronidazole therapy .6, 7 Additionally, nitazoxanide may be proven comparable in efficacy to vancomycin in treating C. difficile colitis, although current sample sizes are t ...
... comparable efficacy to metronidazole in managing Clostridium difficile colitis, in both patients responsive and resistant to metronidazole therapy .6, 7 Additionally, nitazoxanide may be proven comparable in efficacy to vancomycin in treating C. difficile colitis, although current sample sizes are t ...
6_Pain and Inflammation_Afferent andf Efferent Nervous System
... • Maximizing therapeutic effects • Confirm diagnosis of type of headache the patient is having. • Administer drug as soon as headache begins. • Minimizing adverse effects • Assess the patient for a history of cardiovascular or cerebrovascular disorder. • After administering sumatriptan, monitor for ...
... • Maximizing therapeutic effects • Confirm diagnosis of type of headache the patient is having. • Administer drug as soon as headache begins. • Minimizing adverse effects • Assess the patient for a history of cardiovascular or cerebrovascular disorder. • After administering sumatriptan, monitor for ...
THE TITLE: Pharmacokinetic Drug Interaction with Gemfibrozil
... the pharmacokinetic parameters of rosiglitazone among different ethnic groups may be due to genetic variations existing in the drug metabolizing enzymes. The literature also indicated that the CYP2C8 allele frequencies of Caucasian European or Asian individuals cannot be considered as homogeneous gr ...
... the pharmacokinetic parameters of rosiglitazone among different ethnic groups may be due to genetic variations existing in the drug metabolizing enzymes. The literature also indicated that the CYP2C8 allele frequencies of Caucasian European or Asian individuals cannot be considered as homogeneous gr ...
Afrezza®: Inhaled insulin approved by the FDA
... Begin working within the body faster than injected forms Type 1 and 2 diabetics will still need an injection of longer acting insulin to maintain a basal level for a 24-hour period http://www.nature.com/nbt/journal/v25/n12/full/nbt1207-1331.html ...
... Begin working within the body faster than injected forms Type 1 and 2 diabetics will still need an injection of longer acting insulin to maintain a basal level for a 24-hour period http://www.nature.com/nbt/journal/v25/n12/full/nbt1207-1331.html ...
Conscious_Sedation - ARIN Golden Gate Chapter
... Anti-emetic Milk of Amnesia Coffee Creamer that is also an aphrodisiac Burning on injection Must be kept sterile (like intralipid) Really an anesthetic Wears off by redistribution or metabolism. No reversal Less effective in patients with alcohol exposure. Causes respiratory depression or arrest. Ca ...
... Anti-emetic Milk of Amnesia Coffee Creamer that is also an aphrodisiac Burning on injection Must be kept sterile (like intralipid) Really an anesthetic Wears off by redistribution or metabolism. No reversal Less effective in patients with alcohol exposure. Causes respiratory depression or arrest. Ca ...
Immediate time course of drug effect
... it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a predefined critical value e.g. the time above 50% of Emax. With a low dose (blue lines) t ...
... it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a predefined critical value e.g. the time above 50% of Emax. With a low dose (blue lines) t ...
Antimicrobial tissue concentrations. Infect Dis Clin N Am 17
... cefaclor [21,48], cefpodoxime, and cefixime [49]) in animals and humans have been performed. When piperacillin and ceftriaxone were compared, results showed that the difference between free muscle concentrations of ceftriaxone and its total plasma concentrations was much more significant than that of p ...
... cefaclor [21,48], cefpodoxime, and cefixime [49]) in animals and humans have been performed. When piperacillin and ceftriaxone were compared, results showed that the difference between free muscle concentrations of ceftriaxone and its total plasma concentrations was much more significant than that of p ...
Identification and Analysis of Synthetic Cathinones in Seized Materials
... increased prevalence in forensic drug casework in recent years. This has given rise to both legal and analytical challenges, requiring the need for sensitive, reliable and reproducible methods to detect and identify these substances. However, this has been made more difficult by the lack of affordab ...
... increased prevalence in forensic drug casework in recent years. This has given rise to both legal and analytical challenges, requiring the need for sensitive, reliable and reproducible methods to detect and identify these substances. However, this has been made more difficult by the lack of affordab ...
A New Crescent-shaped Spindle for Drug Dissolution Testing—But
... evaluate the robustness of the technique and its operational relevance to the physiological environment for which it is utilized. This may be the cause of the lack of success of the apparently sound concept of dissolution testing. In our laboratory, we became aware of the issue when as a regulatory ...
... evaluate the robustness of the technique and its operational relevance to the physiological environment for which it is utilized. This may be the cause of the lack of success of the apparently sound concept of dissolution testing. In our laboratory, we became aware of the issue when as a regulatory ...
FDA and the Challenge of Alternative Medicine: Realistic
... documentation of its safety and effectiveness against specific diseases and conditions * is not generally taught in U.S. medical schools * is not generally reimbursable by health insurance providers.18 While the broadness of this definition is understandable, it is important to remember that such a ...
... documentation of its safety and effectiveness against specific diseases and conditions * is not generally taught in U.S. medical schools * is not generally reimbursable by health insurance providers.18 While the broadness of this definition is understandable, it is important to remember that such a ...
LETTERS
... port long-term events such as myocardial infarction (MI). However, they did include hypertension, which is commonly accepted as a risk factor for MI. We found the highest hypertension rate with rofecoxib (25 mg). The rate with rofecoxib (12.5 mg) was not significantly different than with placebo or ...
... port long-term events such as myocardial infarction (MI). However, they did include hypertension, which is commonly accepted as a risk factor for MI. We found the highest hypertension rate with rofecoxib (25 mg). The rate with rofecoxib (12.5 mg) was not significantly different than with placebo or ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.