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Full version (PDF file)
Full version (PDF file)

... demonstrated that dorsal agranular insular cortex and dorsal prelimbic cortex project primarily to the dorsal NAc core, while the ventral NAc core is mainly innervated by pathways originating in the ventral prelimbic cortex, ventral agranular insular cortex and olfactory tubercle (Groenewegen et al. ...
How humans distinguish between smells
How humans distinguish between smells

... The particular axons that are activated depend upon which receptor protein is targeted. Each cell produces only one type of receptor protein. In humans, there are approximately 350 different types of receptor proteins produced (Axel, 2006). In other mammals, such as mice, the number of different re ...
The Dialectics of Hebb and Homeostasis within
The Dialectics of Hebb and Homeostasis within

... unfolds slowly, over a time scale of hours to days, which is likely fast enough to compensate for most perturbations these networks normally encounter during experience-dependent development. However, this slowness may be a critical issue for another proposed function of synaptic scaling, which is t ...
Somatodendritic dopamine release - Philosophical Transactions of
Somatodendritic dopamine release - Philosophical Transactions of

... neurons have greater D2 autoreceptor expression versus VTA [100], which is reflected in greater autoreceptor regulation of somatodendritic DA release in SNc than in VTA [38]. It is increasingly recognized that levels of Ca2þ-binding proteins alone are not predictive of cell properties or projection ...
Activity of Bipolar Potential Generation in Paramecium
Activity of Bipolar Potential Generation in Paramecium

... for pulse and plateau with positive and negative potentials. It is found that common modellings are applied to activities in paramecium and neuron with positive and negative potential generation except ion channels. Key-Words: - Paramecium, positive and negative potential generation, swimming direct ...
Cognon Neural Model Software Verification and
Cognon Neural Model Software Verification and

... Systems of Neuromorphic Adaptive Plastic Scalable Electronics (SyNAPSE) is a Defense Advanced Research Projects Agency (DARPA) program with the goal to develop electronic neuromorphic machine technology that scales to biological levels. The ultimate aim is to build an electronic microprocessor syste ...
LESSON 2.3 WORKBOOK How fast do our neurons signal?
LESSON 2.3 WORKBOOK How fast do our neurons signal?

... You just read about research that shows that the human brain, specifically the frontal lobe, is not heavily myelinated until the age of 20. Some scientists argue that teenagers show poor judgment because their brains aren’t fully myelinated. What do you think? Do you agree with the scientists’ argum ...
Chapter 2 - TC Online
Chapter 2 - TC Online

... Copyright © 2015, 2012, 2009 Pearson Education, Inc. All Rights Reserved ...
TESIS DOCTORAL Dynamics and Synchronization in Neuronal Models
TESIS DOCTORAL Dynamics and Synchronization in Neuronal Models

... in detail the structure and concluded that the nervous system was composed of individual neurons rather than a continuum. For this discovery, Cajal was awarded with the 1906 Nobel Price in Medicine. Nowadays, neuroscience is a broad field where many disciplines converge to tackle questions like how ...
Seizure, neurotransmitter release, and gene expression are closely
Seizure, neurotransmitter release, and gene expression are closely

... are epileptogenic and excitotoxic to nerve cells both in vitro and in vivo (Whetsell, 1996). The release of these EAAs from the nerve terminals may be Ca2+ -dependent or -independent, although the mechanisms are not fully understood. Extracellular K+ stimulates the EAA efflux from striatal neurons ( ...
Noradrenergic Suppression of Synaptic Transmission May Influence Cortical Signal-to-Noise Ratio
Noradrenergic Suppression of Synaptic Transmission May Influence Cortical Signal-to-Noise Ratio

... 4-isoxazolepropionic acid (AMPA)] and slow time courses [Nmethyl-D-aspartate (NMDA)]. Each feed-forward interneuron connects to 10 pyramidal cells. These synapses elicit synaptic potentials with both fast (20%) and slow (80%) time courses representing GABAA and GABAB receptors. Both time courses hav ...
the biological perspective
the biological perspective

... part of the axon closest to the soma, the axon hillock, and then proceed down the axon in a kind of chain reaction. (Picture a long hallway with many doors in which the first door opens, then the second, and so on all the way down the hall.) This electrical charge reversal is known as the action pot ...
wood ant (formica lugubris zett.)
wood ant (formica lugubris zett.)

... are characterized by the presence of a subunit pattern of cross-directional electron-opaque lines with a 50- to 70-A periodicity. 5. Morphological signs of chemical transmission are absent in these junctions. O n the other hand, there is a striking similarity in structural organization between soma- ...
mRNA at the Synapse - Journal of Neuroscience
mRNA at the Synapse - Journal of Neuroscience

... synaptosomal RNA and total hippocampal RNA to a synaptophysin probe. Synaptophysin, a synaptic vesicle protein, is synthesized on RER and directed down the axon selectively. As expected, no mRNA for synaptophysin was detected in the synaptosomes. Yet this mRNA was abundant in RNA isolated from the e ...
Sensory Adaptation and Short Term Plasticity as Bayesian
Sensory Adaptation and Short Term Plasticity as Bayesian

... optimal adaptation rule is to normalize the inputs from each presynaptic neuron. Inputs from presynaptic neurons with high excitability will tend to have low gain, while inputs from neurons with low excitability will tend to have high gain. Under this rule, short term increases in firing rate are ty ...
Synaptic Pruning in Development: A Novel Account in Neural Terms
Synaptic Pruning in Development: A Novel Account in Neural Terms

... (e.g. 2 weeks for the macaque monkeys [Bourgeois, 1993]). The changes in synaptic density are not a result of changes in total brain volume, but re ect true synaptic elimination [Rakic et al., 1994]. In some cases, synaptic elimination was shown to be correlated with experience-dependent activity [S ...
Electron microscopical reconstruction of the anterior sensory
Electron microscopical reconstruction of the anterior sensory

... '74). Reconstruction of the wild-type nervous sytem will make i t possible to recognize anatomical lesions in such mutants. Such lesions should aid the task of understanding nervous system function by allowing correlation of behavioral and anatomical defects. In addition, the study of genetically in ...
Presentation
Presentation

... What fraction of regenerated serotonin axons survive long-term and do they attain normal morphology and spatial distribution? ~90% of the regenerated axons survive for 6 months after PCA treatment: They survive at the same rate as uninjured serotonin axons. Furthermore, their distribution and shape ...
Bidirectional propagation of Action potentials
Bidirectional propagation of Action potentials

... different functions to make the nervous system work. We can classify neurons in three functional categories: sensory neurons, motor neurons and interneurons. While sensory neurons convey signals from the body’s periphery to the nervous system, motor neurons communicate commands and decisions form th ...
Glycine Binding Sites of Presynaptic NMDA Receptors May
Glycine Binding Sites of Presynaptic NMDA Receptors May

... Whole cell mEPSCs recordings were performed on 58 pyramidal neurons in layer II/III of the visual cortical slices. Spontaneous mEPSCs in the presence of TTX (0.5 ␮M), strychnine (1 ␮M), and picrotoxin (100 ␮M) were abolished by application of D-APV (50 ␮M) and CNQX (10 ␮M) in the Mg-free ACSF (data ...
Mechanism of Irregular Firing of Suprachiasmatic Nucleus Neurons
Mechanism of Irregular Firing of Suprachiasmatic Nucleus Neurons

... The mechanisms of irregular firing of spontaneous action potentials in neurons from the rat suprachiasmatic nucleus (SCN) were studied in hypothalamic slices using cell-attached and whole cell recording. The firing pattern of spontaneous action potentials could be divided into regular and irregular, ...
Zebrafish and motor control over the last decade
Zebrafish and motor control over the last decade

... hindbrain was essential for later touch responses and swimming (Saint-Amant and Drapeau, 1998). Recent work indicates that this result was mistaken and that the fish can generate swimming and touch responses without the brain, even at later stages (Downes and Granato, 2006). In this respect, zebrafi ...
button - TestbankEbook
button - TestbankEbook

... d. bipolar e. motor Difficulty: 2 Question ID: 2.1-9 Page Ref: 30 Topic: Neurons Skill: Factual Answer: a. multipolar Rationale: The multipolar neuron is the most common neuron in the central nervous system. 2.1-10. The portion of a neuron that carries information toward the cell body is the a. dend ...
Sample
Sample

... d. bipolar e. motor Difficulty: 2 Question ID: 2.1-9 Page Ref: 30 Topic: Neurons Skill: Factual Answer: a. multipolar Rationale: The multipolar neuron is the most common neuron in the central nervous system. 2.1-10. The portion of a neuron that carries information toward the cell body is the a. dend ...
Central Neuropeptide Y Signaling Ameliorates N
Central Neuropeptide Y Signaling Ameliorates N

... Abstract—Neuropeptide Y is a potent inhibitory neurotransmitter expressed in the central neurons that control blood pressure. NO also serves as an inhibitory neurotransmitter, and its deficit causes sympathetic overactivity, which then contributes to hypertension. This study tested the hypothesis th ...
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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission. They transmit signals across a chemical synapse, such as in a neuromuscular junction, from one neuron (nerve cell) to another ""target"" neuron, muscle cell, or gland cell. Neurotransmitters are released from synaptic vesicles in synapses into the synaptic cleft, where they are received by receptors on other synapses. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available from the diet and only require a small number of biosynthetic steps to convert them. Neurotransmitters play a major role in shaping everyday life and functions. Their exact numbers are unknown but more than 100 chemical messengers have been identified.
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