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... • polyploidy is common in plants - but not animals • polyploids are more normal in appearance than aneuploids • large-scale chromosomal alterations in humans and other mammals often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders – plants tolerate such gene ...
... • polyploidy is common in plants - but not animals • polyploids are more normal in appearance than aneuploids • large-scale chromosomal alterations in humans and other mammals often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders – plants tolerate such gene ...
Acquired Copy Number Alterations in Adult Acute Myeloid Leukemia
... Of the CNAs <5 Mb (the lower limit of detection by cytogenetics), 38% (33 out of 88) contained at least one cancer- or AML/MDS-associated gene (52 total cancer- or AML/MDS-associated genes in 88 segments), which was significantly more than the 31 genes expected to occur in 88 size-matched segments r ...
... Of the CNAs <5 Mb (the lower limit of detection by cytogenetics), 38% (33 out of 88) contained at least one cancer- or AML/MDS-associated gene (52 total cancer- or AML/MDS-associated genes in 88 segments), which was significantly more than the 31 genes expected to occur in 88 size-matched segments r ...
Coexpression of Linked Genes in Mammalian
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
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... Enhancer of zeste, Jones and Gelbart, 1990) embryos (data not shown). The effects of Pc group mutations are synergistic in that embryos homozygous for two or three weak mutations show strong homeotic transformation (Jürgens, 1985). To test whether such synergy might enhance some of the weak effects ...
... Enhancer of zeste, Jones and Gelbart, 1990) embryos (data not shown). The effects of Pc group mutations are synergistic in that embryos homozygous for two or three weak mutations show strong homeotic transformation (Jürgens, 1985). To test whether such synergy might enhance some of the weak effects ...
15_detaillectout
... ? Morgan crossed F1 heterozygous females (b bvg vg) with homozygous recessive males (bbvgvg). ? According to independent assortment, this should produce four phenotypes in a 1:1:1:1 ratio. ? Surprisingly, Morgan observed a large number of wild-type (gray-normal) and double-mutant (black-vestigial) f ...
... ? Morgan crossed F1 heterozygous females (b bvg vg) with homozygous recessive males (bbvgvg). ? According to independent assortment, this should produce four phenotypes in a 1:1:1:1 ratio. ? Surprisingly, Morgan observed a large number of wild-type (gray-normal) and double-mutant (black-vestigial) f ...
Sex Chromosomes and Sex
... 1) The only monosomy that is viable through gestation, but 90% of conceptuses are not carried to term. 2) Single X chromosome is maternal in origin in 70–80%; thus, the paternallytransmitted sex chromosome is lacking 3) Associated with the Turner phenotype of webbed neck, shield chest, coarctation o ...
... 1) The only monosomy that is viable through gestation, but 90% of conceptuses are not carried to term. 2) Single X chromosome is maternal in origin in 70–80%; thus, the paternallytransmitted sex chromosome is lacking 3) Associated with the Turner phenotype of webbed neck, shield chest, coarctation o ...
Genome-wide RNAi Robert Barstead
... function of about 90% of the genes on C. elegans chromosome I. Their results, described below, are a spectacular validation of the value of genome-wide RNAi screens. The Hyman group synthesized dsRNA for 2232 genes on C. elegans chromosome III, representing about 96% of the total number of protein-c ...
... function of about 90% of the genes on C. elegans chromosome I. Their results, described below, are a spectacular validation of the value of genome-wide RNAi screens. The Hyman group synthesized dsRNA for 2232 genes on C. elegans chromosome III, representing about 96% of the total number of protein-c ...
Chromosomal Theory and Genetic Linkage
... frequencies, according to the Mendelian concept of independent assortment. new allele combinations, the genotypes Ab and aB are recombination during meiosis. ...
... frequencies, according to the Mendelian concept of independent assortment. new allele combinations, the genotypes Ab and aB are recombination during meiosis. ...
Chromosomal Theory and Genetic Linkage
... frequencies, according to the Mendelian concept of independent assortment. new allele combinations, the genotypes Ab and aB are recombination during meiosis. ...
... frequencies, according to the Mendelian concept of independent assortment. new allele combinations, the genotypes Ab and aB are recombination during meiosis. ...
Cluster analysis
... Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diagnosis. Also, it is likely that the existing classes are heterogeneous. DNA microarrays may be used to characteri ...
... Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. In spite of recent progress, there are still uncertainties in diagnosis. Also, it is likely that the existing classes are heterogeneous. DNA microarrays may be used to characteri ...
The Complete Mitochondrial DNA (mtDNA) of the Donkey and
... common chimpanzee, showed that the relative evolutionary rate of individual peptide-coding genes varies among different species-pairs and modes of comparison. The findings show that the superimposition of sequence data ...
... common chimpanzee, showed that the relative evolutionary rate of individual peptide-coding genes varies among different species-pairs and modes of comparison. The findings show that the superimposition of sequence data ...
Nucleotide Bias Causes a Genomewide Bias in the Amino Acid
... Wilquet and Van de Casteele 1999). All of these studies, despite the fact that they were based on a wide variety of different genes and proteins, provide evidence for a significant correlation between DNA composition and protein composition. We wished to test the generality of these correlations thr ...
... Wilquet and Van de Casteele 1999). All of these studies, despite the fact that they were based on a wide variety of different genes and proteins, provide evidence for a significant correlation between DNA composition and protein composition. We wished to test the generality of these correlations thr ...
33-1-001
... 5 weak plants in the F2. These results are the same as those reported in the F2 of a cross between an Indian cultivar and a Japanese cultivar 8>. On the other hand, a duplicate rece.ssive gene system with a segregation ratio of 15 normal : I weak or chlorotic plants in the F2 has also been reported ...
... 5 weak plants in the F2. These results are the same as those reported in the F2 of a cross between an Indian cultivar and a Japanese cultivar 8>. On the other hand, a duplicate rece.ssive gene system with a segregation ratio of 15 normal : I weak or chlorotic plants in the F2 has also been reported ...
Continuous Representations of Time Series Gene Expression Data
... sampled non-uniformly, and measure biological processes that exhibit temporal variation. In many applications, researchers may face the problem of reconstructing unobserved gene expression values. Values may not have been observed for two reasons. First, errors may occur in the experimental process ...
... sampled non-uniformly, and measure biological processes that exhibit temporal variation. In many applications, researchers may face the problem of reconstructing unobserved gene expression values. Values may not have been observed for two reasons. First, errors may occur in the experimental process ...
Chapter. 15(Chromosomal Basis of Inheritance)
... Concept 15.3: Linked genes tend to be inherited together because they are located near each other on the same chromosome. • Genes located on the same chromosome that tend to be inherited together are called linked genes. • Morgan did other experiments with fruit flies to see how linkage affects inh ...
... Concept 15.3: Linked genes tend to be inherited together because they are located near each other on the same chromosome. • Genes located on the same chromosome that tend to be inherited together are called linked genes. • Morgan did other experiments with fruit flies to see how linkage affects inh ...
Molecular Evolution in Nonrecombining Regions of the Drosophila
... codon usage bias, increased gene length, an increased level of nonsynonymous polymorphism relative to synonymous polymorphism, and a reduced incidence of positive selection. However, in Drosophila melanogaster and its relatives, these studies have mostly focused on the small dot (fourth) chromosome, ...
... codon usage bias, increased gene length, an increased level of nonsynonymous polymorphism relative to synonymous polymorphism, and a reduced incidence of positive selection. However, in Drosophila melanogaster and its relatives, these studies have mostly focused on the small dot (fourth) chromosome, ...
Chapter 11 and 12 from Campbell Biology 10th Edition By Keshara
... Inheritance patterns are often more complex than predicted by simple Mendelian Genetics >extending Mendelian Genetics for a single gene inheritance of characters determined by a single gene deviates from simple Mendelian patterns when alleles are not completely dominant or recessive , when a parti ...
... Inheritance patterns are often more complex than predicted by simple Mendelian Genetics >extending Mendelian Genetics for a single gene inheritance of characters determined by a single gene deviates from simple Mendelian patterns when alleles are not completely dominant or recessive , when a parti ...
Genoplante 2007, ANR-07-GPLA-002
... biosynthesis to the external leucine excess or depletion, showing that the adaptive regulation of gene expression is conserved in a highly reduced genome. In the aphid host, the analysis, in single individuals, of tissue-distribution of gene knock-down after RNAi treatment (against a cathepsin-L tar ...
... biosynthesis to the external leucine excess or depletion, showing that the adaptive regulation of gene expression is conserved in a highly reduced genome. In the aphid host, the analysis, in single individuals, of tissue-distribution of gene knock-down after RNAi treatment (against a cathepsin-L tar ...
TNFα signals through specialized factories where responsive coding
... the large number of p65 foci shown in the supplemental figure. Exactly where do these genes colocalize? Are these colocalization sites actual tx factories, are they a subset of p65 foci which also colocalize with tx factories, are they in fact at other types of well defined nuclear bodies such as sp ...
... the large number of p65 foci shown in the supplemental figure. Exactly where do these genes colocalize? Are these colocalization sites actual tx factories, are they a subset of p65 foci which also colocalize with tx factories, are they in fact at other types of well defined nuclear bodies such as sp ...
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... Fig. 1. Vertebrate Hox genes. There are four clusters of vertebrate Hox genes. Numbers in the boxes represent previous nomenclature. Currently, genes are referred to by their cluster letter (right) and paralogue number (l-13 listed above). At the time of insect/vertebrate divergence, there were betw ...
... Fig. 1. Vertebrate Hox genes. There are four clusters of vertebrate Hox genes. Numbers in the boxes represent previous nomenclature. Currently, genes are referred to by their cluster letter (right) and paralogue number (l-13 listed above). At the time of insect/vertebrate divergence, there were betw ...
The structure of a gene co-expression network reveals biological
... partial correlations [8]. Unlike in ontological enrichment analysis or bibliographic networks, information available on both functionally known and unknown genes is used for the network definition. Once the network is given, a full analysis of its structure could be performed, from either the point ...
... partial correlations [8]. Unlike in ontological enrichment analysis or bibliographic networks, information available on both functionally known and unknown genes is used for the network definition. Once the network is given, a full analysis of its structure could be performed, from either the point ...
Essential gene
Essential genes are those genes of an organism that are thought to be critical for its survival. However, being essential is highly dependent on the circumstances in which an organism lives. For instance, a gene required to digest starch is only essential if starch is the only source of energy. Recently, systematic attempts have been made to identify those genes that are absolutely required to maintain life, provided that all nutrients are available. Such experiments have led to the conclusion that the absolutely required number of genes for bacteria is on the order of about 250-300. These essential genes encode proteins to maintain a central metabolism, replicate DNA, translate genes into proteins, maintain a basic cellular structure, and mediate transport processes into and out of the cell. Most genes are not essential but convey selective advantages and increased fitness.