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Prescribing exercise interventions for patients with
Prescribing exercise interventions for patients with

... of 4 points [95% CI 2 to 5] on a 0–100 scale [100 was the maximum quality of life]). For osteoarthritis of the hip, a recent Cochrane review of 10 RCTs of land-based exercise compared with no exercise (of which seven were deemed to have a low risk of bias) showed evidence of benefit.11 High-quality ...
Relationship between significant coronary artery disease and
Relationship between significant coronary artery disease and

Impairment of coronary flow reserve in aortic stenosis
Impairment of coronary flow reserve in aortic stenosis

... As an example, Fig. 2 shows the pressure waveforms given by the two aforementioned models with a native aortic valve (top) or a very severe AS (EOA ⫽ 0.4 cm2, bottom), both under normal flow conditions. Finally, the third model consists of a new lumped-parameter representation of the inflow in the l ...
Predictors for Regression of Large Secundum Atrial Septal Defects
Predictors for Regression of Large Secundum Atrial Septal Defects

... the maximal diameter may have been hampered by the oval shape of defects and cardiac cycle. For the median size of ASDs in the neonates or young infants, an ASD diameter between 5-8 mm could be relatively large when comparing this to intact interatrial septal length. Besides the evaluation of an abs ...
2016 Canadian Cardiovascular Society
2016 Canadian Cardiovascular Society

... individuals as traditional cardiovascular risk factors such as dyslipidemia, are most strongly associated with premature CVD.8,9 It has been estimated that many younger individuals (especially those with elevated LDL-C) will benefit substantially from long-term therapy even if they are at low risk o ...
Current treatment of ventricular arrhythmias: State of
Current treatment of ventricular arrhythmias: State of

... delayed detection and high rate groups, respectively. The reasons for the increase in mortality are not clear, but arrhythmias detected and treated by the ICD have been associated with reduced survival and increased heart failure hospitalizations in other studies.45–47 Arrhythmias, whether spontaneo ...
ACC/AHA Guidelines for the Evaluation and Management of
ACC/AHA Guidelines for the Evaluation and Management of

... development of HF and that therapeutic interventions performed even before the appearance of left ventricular dysfunction or symptoms can reduce the morbidity and mortality of HF. This classification system is intended to complement but not to replace the New York Heart Association (NYHA) functional ...
Effects of right ventricular pacing on left ventricular ejection fraction
Effects of right ventricular pacing on left ventricular ejection fraction

... Baseline characteristics of the 269 patients included in the study are shown in table 1. Mean age was 71± 12 years with a range from 18.4 years to 90.8 years. A dual-chamber pacemaker had been implanted in 234 (87%) patients and a single-chamber pacemaker in 35 (13%) patients, respectively. Most pat ...
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A

AHA/ADA Scientific Statement
AHA/ADA Scientific Statement

... In adult patients, lipid levels should be measured at least annually and more often if needed to achieve goals. In adults under the age of 40 years with low-risk lipid values (LDL-C ⬍100 mg/dL, HDL-C ⬎50 mg/dL, and triglycerides ⬍150 mg/dL), lipid assessments may be repeated every 2 years. Lifestyle ...
Perioperative assessment of left ventricular function in patients with
Perioperative assessment of left ventricular function in patients with

... results suggest that the abnormalities in contractility of left ventricular myocardium are responsible for the impaired myocardial function in patients with mitral stenosis and that such impairment is clinically significant. Gash et al 10 in 1983 reported that the patients with MS usually exhibit re ...
16 Myocardial Disease
16 Myocardial Disease

... SAM begins very early in systole, when the outflow tract velocity is normal [20]. The relatively low velocity is unlikely to generate significant Venturi forces; conversely, there will be increased contact of the flowing blood with the valve, augmenting the drag effect. Flow drag may therefore be th ...
Ann Thorac Surg
Ann Thorac Surg

... Extracardiac conduit Fontan vs lateral tunnel)was performed in 63%; in all, 65% were fenestrated. In multivariable analysis the extracardiac conduit Fontan was associated with significantly higher Fontan takedown/revision and Fontan failure and longer postoperative hospital stay.  Conclusions: The ...
The Effect of Intensified Low Density Lipoprotein Cholesterol
The Effect of Intensified Low Density Lipoprotein Cholesterol

... Figure 2. Kaplan-Meier analyses for freedom from myocardial infarction in all AMI patients. Panel A showed the patients with 3-month low density lipoprotein-cholesterol (LDL-C) decrease ‡ 40% had higher rate of freedom from myocardial infarction at 5-year follow-up than the patients with 3-month LDL ...
Management of the postoperative Fontan patient
Management of the postoperative Fontan patient

Cardiovascular Consequences of Obese and Nonobese Obstructive
Cardiovascular Consequences of Obese and Nonobese Obstructive

... that OSA is one of the causative factors in systemic hypertension. Large prospective longitudinal studies help us understand the link between OSA and hypertension (HTN). The Wisconsin Sleep Cohort Study is a population-based longitudinal study that was initiated in the 1980s, and looked at the natur ...
Cardiac Arrhythmias
Cardiac Arrhythmias

... b. β-blocking agents—β-blockers such as metoprolol or esmolol slow SA node impulse formation and slow conduction through the AV node. These medications should be used with caution in patients with a history of severe reactive airway disease and CHF. Metoprolol is an alternative to calcium channel bl ...
Syncytium in Drosophila melanogaster
Syncytium in Drosophila melanogaster

... lethality at the peri-implantation stage, before cardiogenesis [11,12]. In zebrafish, the global knock-down of Kind2 causes cardiac hyperplasia, disrupts intercalated disc formation and significantly reduces cardiac contractility [11]. These findings link Kind2 with the development of a functional c ...
AHA Scientific Statement
AHA Scientific Statement

... become apparent because of superimposed acquired heart disease or as an incidental finding. Operative or catheter interventional therapy for these patients may be more complex than if the problem had been addressed in childhood and may have to be combined with additional procedures, for example, cor ...
2014 Life threatening causes of syncope
2014 Life threatening causes of syncope

... LQTS is an inherited channelopathy characterized by QT interval prolongation and an increased risk of syncope and sudden death. This often under diagnosed condition has a prevalence of approximately 1:2500 and a ten-year mortality rate as high as 50% in untreated, symptomatic patients (Sauer et al., ...
Plasma fibrinogen lever and risk of Coronary Heart Disease among
Plasma fibrinogen lever and risk of Coronary Heart Disease among

... levels in a large cohort of Chinese patients with CHD and to examine the relationship of fibrinogen. Methods: We performed a meta-analysis of case-control and prospective studies of plasma fibrinogen level in relation to CHD risk in electronic database of Medline, EMBase, the Cochrane Library and CN ...
Pulmonary Vascular Resistance as Assessed by Bicycle Stress
Pulmonary Vascular Resistance as Assessed by Bicycle Stress

... Background—Volume overload of the pulmonary circulation in patients with atrial septal defect (ASD)-type secundum causes pulmonary vascular disease over a long period of time. This study aimed at (1) evaluating pulmonary vascular resistance (PVR) and (2) investigating the relation between PVR and ex ...
AHA Scientific Statement
AHA Scientific Statement

... become apparent because of superimposed acquired heart disease or as an incidental finding. Operative or catheter interventional therapy for these patients may be more complex than if the problem had been addressed in childhood and may have to be combined with additional procedures, for example, cor ...
Metabolic Response during Impending Myocardial
Metabolic Response during Impending Myocardial

... control period to 101% during ischemia and a decrease in the oxygen-extraction ratio for glucose from 33 to 25%. In patients with a severe systemic response to acute myocardial infarction, insulin suppression can be almost complete, and this will reduce the availability of glucose to myocardial cell ...
Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?
Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?

... matched controls. The incidence rates for any heart failure diagnosis were 4.0 per 1000 person-years in diabetic patients compared to 0.97 per 1000 person-years in controls [24]. These studies may thus support the conclusion of an increased risk of HF in type 1 diabetic subjects. And this may be the ...
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