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Heart Failure
Heart Failure

... visits per year. The direct and indirect costs of HF in the United States are staggering; in 2010 they were estimated to be US $39.2 billion (8). The estimated lifetime cost of HF per individual patient is $110,000/year (-2008 US dollars), with more than three-fourths of this cost consumed by in-hos ...
EUROPEAN HEART FAILURE AWARENESS DAY 2014 REPORT
EUROPEAN HEART FAILURE AWARENESS DAY 2014 REPORT

... 100 women and 4 in every 100 men. It accounts for 5% of all emergency hospital admissions and 2% of all NHS hospital bed days. Quality of Life – Heart failure causes greater reduction in quality of life than any other chronic medical condition. Inadequately treated heart failure has a similar surviv ...
ACC/AHA Guidelines for the Evaluation and Management of
ACC/AHA Guidelines for the Evaluation and Management of

... HF, and nearly 500,000 patients are diagnosed with HF for the first time each year. The disorder is the underlying reason for 12 to 15 million office visits and 6.5 million hospital days each year (1). During the last 10 years, the annual number of hospitalizations has increased from approximately 5 ...
Echo-Doppler–derived indexes of ventricular stiffness and ventriculo
Echo-Doppler–derived indexes of ventricular stiffness and ventriculo

... elastance (Ea), LV end-systolic elastance (Ees) and ventricular–vascular coupling index (VVI). Results: AF occurred in 57 (16.3 %) patients over a median follow up of 30.3 months. Echo-Doppler–derived parameters of ventricular stiffness and ventriculo-arterial interaction were closely associated wit ...
A simple test of one minute heart rate variability during deep
A simple test of one minute heart rate variability during deep

... The cardiovascular system is influenced by the autonomic nervous system (ANS). The two neural mechanisms for controlling heart rate are the sympathetic nervous system, which has positive chronotropic, ionotropic, dromotropic and bathmotropic effect where as the parasympathetic nervous system have ne ...
New Advances in the Diagnosis and Management of Cardioembolic
New Advances in the Diagnosis and Management of Cardioembolic

... when intra-aortic balloons were used. Thrombolytics or heparin use before PCI was independently associated with periprocedural stroke. Stroke was independently associated with in-hospital death, renal failure, and the new need for hemodialysis. Also, the amount of contrast agent used in those with s ...
Clinical Practice Guidelines on UA/NSTEMI 2002
Clinical Practice Guidelines on UA/NSTEMI 2002

... the left chest and may radiate to the jaw or down the upper limb. It may be crushing, pressing or burning in nature. The severity of the pain is variable. It is difficult to differentiate between symptoms of STEMI and UA / NSTEMI. Some patients may present in acute left ventricular failure. Atypical ...
Evaluation of independent prognostic importance of hyperuricemia
Evaluation of independent prognostic importance of hyperuricemia

... acid level greater than 7 mg/dl) as an independent short term (in hospital) prognostic factor after acute myocardial infarction (AMI). Methods: Included in the study were 2218 patients who were hospitalized with well established AMI from June 1996 through to December 2002 in the Coronary Care Unit o ...
Should everyone with an ejection fraction less than or equal to 30
Should everyone with an ejection fraction less than or equal to 30

... without an ICD.14 Although the average EF was 24%, 2-year mortality was ⬍10% in both treatment groups, and no benefit was demonstrated with ICD therapy. The DEFibrillators In Non-Ischemic cardiomyopathy Treatment Evaluation (DEFINITE) trial enrolled 458 patients with nonischemic dilated cardiomyopat ...
Can the block help the beat? Beta blockers for ventricular fibrillation.
Can the block help the beat? Beta blockers for ventricular fibrillation.

... • Landiolol used after traditional standards of care failed • Initiated landiolol at very low dose • Specific reassessment period after administration • Clinical features used for evaluation • Lack of control • Differences in baseline characteristics between survivors and non-survivors • Sample size ...
Efficacy of Two Streptokinase Formulations in Acute Myocardial
Efficacy of Two Streptokinase Formulations in Acute Myocardial

... Heberkinasa (HBK) or Streptase (STP), in patients with acute myocardial infarction who needed thrombolysis. Thrombolysis success was evaluated angiographically and/or clinically. Clinical follow-up was done 30 days after thrombolysis. Results: We randomly allocated 221 patients with a mean age of 56 ...
Vasoactive Agents
Vasoactive Agents

... agents and remain important and useful today although there can be some negative consequences of their use (Table 4). A major side effect is an increase Table 3. Older therapeutic medications ...
Atrial Fibrillation and Atrial Flutter
Atrial Fibrillation and Atrial Flutter

...  Patients with atrial fibrillation have an erratic heart rhythm that sounds like “tennis shoes in a dryer” when listening to the chest with a stethoscope (procedure known as “auscultation”)  Heart sounds when listening to the heart with a stethoscope sound like “Lub Dub;” the first heart sound is ...
atrial fibrillation and atrial flutter
atrial fibrillation and atrial flutter

...  Patients with atrial fibrillation have an erratic heart rhythm that sounds like “tennis shoes in a dryer” when listening to the chest with a stethoscope (procedure known as “auscultation”)  Heart sounds when listening to the heart with a stethoscope sound like “Lub Dub;” the first heart sound is ...
Nutritional intake and oxidative stress in chronic heart failure
Nutritional intake and oxidative stress in chronic heart failure

... Between 35 and 53% of patients with chronic heart failure (CHF) suffer from some form of malnutrition [1e3] and cardiac cachexia is a strong independent risk factor for mortality in such patients [4]. Several mechanisms may play a role in the development of malnutrition and cachexia in patients with ...
An Overview of Current Cardiac Resynchronization Therapy
An Overview of Current Cardiac Resynchronization Therapy

... or II symptoms and non-LBBB pattern with QRS duration < 150 ms.9,10 (Level of Evidence: B) 2. CRT is not indicated for patients whose comorbidities limit survival with good functional capacity to less than 1 year.1 (Level of Evidence: C) The most significant changes in the present document compared ...
The Heart Myotonic Dystrophy - Myotonic Dystrophy Support Group
The Heart Myotonic Dystrophy - Myotonic Dystrophy Support Group

... 1) Mathieu J, Allard P, Potvin L, et al. 10-year study of mortality in a cohort of patients with myotonic dystrophy. Neurology. 1999;52:1658-62. ...
beyond ncep atp iii: lessons learned and future directions
beyond ncep atp iii: lessons learned and future directions

... with LDL cholesterol lowering to near 100 mg/dL versus approximately 75 mg/dL. The Incremental Decrease in Endpoints through Aggressive Lipid Lowering (IDEAL) study compares atorvastatin 80 mg versus simvastatin 20 mg or 40 mg in 8600 patients. In the Study of Effectiveness of Additional Reductions ...
Heart Failure
Heart Failure

... recording on a daily basis (weight, blood pressure, pulse)? • How will I know if my condition is getting worse? When should I call 9-1-1? • What is my goal weight? • If I notice that I am weighing more, at what point should I call you? • How much exercise can I do and what activities are best? Is it ...
ASH v2 i4 - American Society of Hypertension
ASH v2 i4 - American Society of Hypertension

... of 50 to 100 mg qd, on cardiovascular morbidity and mortality in patients with essential hypertension and electrocardiographically (ECG) documented left ventricular hypertrophy (LVH). Additional treatment may be given as open-label hydrochlorothiazide 12.5 to 25 mg and, if needed, any other antihype ...
Opmaak 1 - UZ Leuven
Opmaak 1 - UZ Leuven

... Key words. Complete heart block ; congenital heart disease ; late recovery ; pacemaker ; pediatric cardiac surgery. Abstract. Objectives : Pacemaker implantation is a standard recommendation for patients with persistent complete heart block with congenital heart disease. This study was performed to ...
Pathophysiology of Heart failure
Pathophysiology of Heart failure

... ↑ afterload: due to - elevation of arterial resistance - ↑ ventricular size - myocardial hypotrophy ↓ afterload: due to - ↓ arterial resistance - myocardial hypertrophy - ↓ ventricular size ...
Clinical Applications of Myocardial Perfusion Spect
Clinical Applications of Myocardial Perfusion Spect

... Myocardial perfusion SPECT, especially with pharmacologic stress substituted for exercise, serves as a valuable means to risk stratify patients prior to peripheral vascular surgery and other major surgical procedures (12). In patients with evidence of myocardial ischemia on myocardial perfusion SPE ...
Patients with atrial fibrillation and low risk of stroke: do they really
Patients with atrial fibrillation and low risk of stroke: do they really

... stroke. Anticoagulation therapy has been shown to reduce this risk; therefore, the treatment should be lifelong. However, the risk in patients with nonvalvular AF is not equally distributed, and there is a population of patients at low risk. According to the current guidelines, the decision on the n ...
030403 Eplerenone, a Selective Aldosterone Blocker, in Patients
030403 Eplerenone, a Selective Aldosterone Blocker, in Patients

... was measured 48 hours after the initiation of treatment, at one, four, and five weeks, at all scheduled study visits, and within one week after any change of dose. Information about adverse events and concurrent medications was recorded at every visit. All patients who underwent randomization were f ...
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