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Pharmacology Jeopardy Part 1
Pharmacology Jeopardy Part 1

... – Occurs in sulfonamides and other drugs that are normally highly bound to albumin in adults ...
Treating Allergies
Treating Allergies

... to get symptom relief, try taking 20 mg of our Best Buys (two pills or portions). (Note that this increases your chances of having side effects, including feeling drowsy.) If that does not work, talk to your doctor. Both the old and newer You might need to try another class of medicine. antihistamin ...
药理概论2
药理概论2

... Amount of drug passing through BBB Increases when inflammation or larger doses used ...
HOMOEOPATHIC PHARMACOPOEIA CONVENTION OF THE
HOMOEOPATHIC PHARMACOPOEIA CONVENTION OF THE

... rolling basis, rather than an entirely new edition at periodic intervals. This new service is called the Homoeopathic Pharmacopoeia Revision Service. For convenience, we refer to it as the “HPUS”. ...
Factors influencing drug effects in older adults
Factors influencing drug effects in older adults

... 1. Withdraw unnecessary drugs or reduce doses if appropriate 2. Determine whether „manifestations of the old age“ such as confusion, urination problems, dizzines, insomnia, etc are not due to drugs 3. In general, begin therapy with low doses 4. If possible avoid administration of drugs inappropriate ...
Chapter 1 Opener
Chapter 1 Opener

... • When a drug is used as a control condition for a new drug that is being tested – One quarter to half as large of an effect than when the drugs efficacy was initially tested. ...
Phenytoin
Phenytoin

... given enterally rather than intravenously. However, in patients receiving enteral feeding, studies suggest that significantly lower plasma concentrations than expected are attained. This is due to the formation of insoluble chelates with divalent ions (calcium, magnesium, etc) in the feeds, thus red ...
Introduction to Pharmacology NAPNES Guidelines
Introduction to Pharmacology NAPNES Guidelines

... – Maintains integrity of body functions while patient recovering from illness – Examples • Providing fluids/electrolytes to prevent dehydration – In vomiting or diarrhea ...
Drug Identification, continued
Drug Identification, continued

... ® Any drugs taken in excessive amounts and causes illness or death is classified as a poison ® Legal drugs that are taken solely for pleasure are considered illicit drugs. ® “Controlled substances” are drugs that are restricted by law. ® The Controlled Substances Act is a law that was enacted in 197 ...
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drug metabolism
drug metabolism

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Non-Price Competition in “Substitute" Drugs: The
Non-Price Competition in “Substitute" Drugs: The

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drugs affecting breast milk and lactation
drugs affecting breast milk and lactation

... • It also Provides the baby with immunoglobulins (IgA, IgM) that are essential for protection against gastroenteritis. ...
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Routes of Administration
Routes of Administration

... • Your genetic makeup influences how quickly you metabolize different drugs. DNA tests can now determine if you are a normal, slow or fast metabolizer of certain drug categories. • The rate of metabolism of most drugs varies with the concentration of drug in the body: • more metabolized/hr when conc ...
Basic Principles of Pharmacology
Basic Principles of Pharmacology

... Not always required prior to early studies in man unless there is a high suspicion that the drug could be carcinogenic e.g. suspicion of mutagenicity; highly reactive groups on drug; histopathological abnormalities… Required if the use of drug in man for more than one year or +ve mutagenic test ...
alcohol
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Adverse Drug Reactions
Adverse Drug Reactions

... largest cause of mortality in the USA (Lazarou J. et al., 1998) ...
Pharmacokinetics (Excretion of Drugs and factors affecting Excretion
Pharmacokinetics (Excretion of Drugs and factors affecting Excretion

... Net excretion by intestine may be greatly reduced by subsequent reabsorption into the bloodstream of fat-soluble compounds further along the intestines. In this case drugs will undergo the process of excretion all over again and the drug effect is prolonged. This excretion/reabsorption phenomenon is ...
Slide 1
Slide 1

... • Benzodiazepines (BZs) are the most extensively analysed medicinal drugs regarding risk assessment in traffic. • BZs, particularly long half-life acting drugs, in higher therapeutic doses and / or at the start of treatment are most likely to cause an increase in crash risk. • Increased risk of BZs ...
drugs and their effects 15
drugs and their effects 15

... • Household products that produce a high by breathing them in • Trick brain into thinking it is Oxygen when it is really poison but ANY perceived “high” is really the brain shutting down (hypoxia) – Hypoxia: Decrease in the oxygen supply in the bloodstream • Effects: death, dizziness, blackout, trou ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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