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The use of animals in the study of human disease
The use of animals in the study of human disease

... individuals in the UK. It is a crippling disease resulting primarily in a chronic inflammation of joints of the hands, feet, knees, vertebrae or hips. It typically leads to progressive degeneration of the joint tissues with consequent disability and premature death. Although the exact cause of RA is ...
Dengue Fever
Dengue Fever

... Dengue (pronounced den gay) has been a worldwide problem since 1950s in many tropical countries. It is caused by any one of four related viruses transmitted by mosquitoes. There are not yet any vaccines to prevent infection with dengue virus and the most effective protective measures are those that ...
INTRODUCTION The Infectious Disease Control Manual (IDCM) is
INTRODUCTION The Infectious Disease Control Manual (IDCM) is

... Viral hemorrhagic fever (VHF) Plague syndrome (SARS) Yellow fever Diphtheria Any unexpected pattern of cases, suspected cases, deaths or increased incidence of any other disease of major public health concern, because of the severity of disease or potential for epidemic spread, which may indicate a ...
Disney Cruise Line Medical Examination Form
Disney Cruise Line Medical Examination Form

... that the examinee is not suffering from any disease likely to be aggravated by, or render him/her unfit for, service at sea or likely to endanger the health of other persons on board ships, and specifically that the examinee is free from all communicable diseases (including without limitation Tuberc ...
A 7-Year-Old Boy with Heel Pain
A 7-Year-Old Boy with Heel Pain

... with meningococcal disease 7 days (or fewer) prior to the onset of illness should be treated with chemoprophylaxis. Those for whom chemoprophylaxis is recommended include all household contacts, all day care/ nursery school contacts (both children and adults), and all health care workers who had int ...
Заголовок слайда отсутствует
Заголовок слайда отсутствует

... diseases in at least 95% of children who receive 2 shots. Nearly all children who get the MMR vaccine (more than 80%) will have no side effects at all. Of those children who have a side effect, most will have only a mild reaction. Mild side effects of the vaccine include soreness, redness or swellin ...
EBV Disease Post-Renal Transplant and PTLD
EBV Disease Post-Renal Transplant and PTLD

... infections with fungus, EBV, and bacteria. • CMV has been implicated in causing acute and chronic allograft injury. • Highest risk of disease are in D+/R- pairings; use of antilymphocyte antibody preparations. • Prophylaxis with valganciclovir for 3-6 months recommended. • May pre-emptively treat by ...
herpesvirus lecture
herpesvirus lecture

... – more virus shed with active/symptomatic lesions or with immune suppression (may increase HIV acquisition) – shedding occurs on 1-8% of days with no lesions by culture (up to 28% of days by PCR) – Reduced with antivirals (to about 3% of days by PCR) ...
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... health problem ● A leading cause of death and morbidity in all ages, in both developed and developing world ● WHO estimates 11 to 20 M hospitalizations from pneumonia occur each year in developing countries ● At least 1M children die every year from pneumococcal infections – primarily pneumonia and ...
Bloodborne Pathogens
Bloodborne Pathogens

... in the United States. Acute or Chronic Chronic – insidious, slow & without symptoms for 2 or more decades. Symptoms include: jaundice, fatigue, abdominal pain, loss of appetite, intermittent nausea, vomiting. May lead to chronic liver disease, transplant & death. ...
Approach to lymphadenopathy
Approach to lymphadenopathy

... macrophages, leading to enlargement of nodes. There may also be localized infiltration by inflammatory cells in response to an infection of the nodes themselves. This is known as a lymphadenitis. Finally, it is crucial to rule out rarer, more serious causes such as lymphomas or leukemias, which are ...
Increased attention is currently being focused on Western Lower
Increased attention is currently being focused on Western Lower

... Michigan. This area, which previously showed no evidence of Lyme disease activity, has been identified as an area of concern by researchers studying the Blacklegged Tick. Investigations conducted from 2001-2007 have discovered tick populations are being established in these areas, and found Lyme bac ...
Diagnosing Disease Problems In Livestock
Diagnosing Disease Problems In Livestock

... or humanely put to sleep, a live representative animal from a herd experiencing a disease problem. This will help to ensure that the animal's tissues are fresh. In addition, a post-mortem examination on an animal that has just become ill and has not been treated for disease is often needed. This is ...
SEICRS explorations
SEICRS explorations

... • Data often recorded in discrete time intervals • Can match natural timescale of system, e.g. generation time or length of a season • Easy to code (simple loop) and intuitive • Note: can yield unexpected behaviour which may or may not be biologically relevant (e.g. chaos). ...
COMMUNICABLE DISEASES AND INFECTIOUS DISEASE CONTROL
COMMUNICABLE DISEASES AND INFECTIOUS DISEASE CONTROL

... person. Any theoretical transmission would most likely involve exposure of open skin lesions or mucous membranes to blood or other body fluids of an infected person. It is possible for individuals who have no symptoms of disease to have infectious organisms present in their body fluids. These indivi ...
Custom, culture and health in the tropics
Custom, culture and health in the tropics

... situation relating to cooking temperature and infection is demonstrated by the example of Enterohaemorrhagic Escherichia coli 0157:H7 and hamburger cooking in the USA. Here legislation relating to cooking temperatures for commercially sold “takeaway-type” hamburgers was not adhered to, resulting in ...
14RLattesCaseTID
14RLattesCaseTID

... necrosis  The patient was discharged with: • Bitemporal hemianopsia  Treated for 2 years for CNS edema and inflammation with no side effects of medication  Is on 4md/d of C-ST ...
Advances in Environmental Biology  Jantraporn Suksawat and Surapol Naowarat
Advances in Environmental Biology Jantraporn Suksawat and Surapol Naowarat

... conjunctivitis in India Ocean Islands, illustrating that returning travellers may serve as sentinels for infectious disease outbreak in tropical areas where the laboratory facilities are limited. During October 2010, Egypt reported an outbreak of AHC consisting of 1831 cases being reported from gove ...
感染症疫学 Infectious Disease Epidemiology Graduate School of
感染症疫学 Infectious Disease Epidemiology Graduate School of

... Attendance 30 %, Exam 70% (To get credit 60% in total will be required) [Textbook] Not used No text book will be used. [Reference books, etc.] (Reference books) (1)Bonita R, Beaglehole R., Kjellström. Basic Epidemiology 2nd edition, WHO, 2006. (2)Kramer A, Kretzschmar M, Krickeberg. Modern infectiou ...
Infection Control, Medical Asepsis, and Sterilization[1].
Infection Control, Medical Asepsis, and Sterilization[1].

... 3. The peak stage – (clinical stage) the disease reaches its highest point of development. Ex. Severe aches, chills, vomiting, etc. 4. The recovery stage – symptoms have all but completely vanished; pathogen has been mostly eliminated. ...
Left tender Cervical Mass
Left tender Cervical Mass

... irritability, difficulty sleeping, and decreased appetite, may include erythema and swelling of the nasal mucosa, as well as moderate anterior cervical lymphadenopathy. ...
Observation on the outbreak of lumpy skin disease in Ethiopia
Observation on the outbreak of lumpy skin disease in Ethiopia

... There had been indications in the past years on the existence of lumpy skin disease in Ethiopia. But attempts to isolate the virus had never been carried out. Hence this has hindered to reach a final diagnosis and declare the occurrence of the disease. The present study on the isolation of the virus ...
AH LIVER & GALLBLADDER
AH LIVER & GALLBLADDER

... contact or exposure to contaminated blood. ► D only occurs in association with B ► B,C,D – lead to chronic Hepatitis ...
cervical lymphadenopathy
cervical lymphadenopathy

... below clavicles, so solitary metastatic nodes can be from primary tumors of breast, lungs & stomach FEATURES  Usually painless Detected on clinical examination Feel stony hard & freely movable till they penetrate node capsule & Invade surrounding tissues ...
A neighbor*s tick bite and the risk of Lyme
A neighbor*s tick bite and the risk of Lyme

... lives in (or is endemic to) the Northeastern US (including our home of Pittsburgh) ...
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Chagas disease



Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protozoan Trypanosoma cruzi. It is spread mostly by insects known as triatominae or kissing bugs. The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild and may include fever, swollen lymph nodes, headaches, or local swelling at the site of the bite. After 8–12 weeks, individuals enter the chronic phase of disease and in 60–70% it never produces further symptoms. The other 30 to 40% of people develop further symptoms 10 to 30 years after the initial infection, including enlargement of the ventricles of the heart in 20 to 30%, leading to heart failure. An enlarged esophagus or an enlarged colon may also occur in 10% of people.T. cruzi is commonly spread to humans and other mammals by the blood-sucking ""kissing bugs"" of the subfamily Triatominae. These insects are known by a number of local names, including: vinchuca in Argentina, Bolivia, Chile and Paraguay, barbeiro (the barber) in Brazil, pito in Colombia, chinche in Central America, and chipo in Venezuela. The disease may also be spread through blood transfusion, organ transplantation, eating food contaminated with the parasites, and by vertical transmission (from a mother to her fetus). Diagnosis of early disease is by finding the parasite in the blood using a microscope. Chronic disease is diagnosed by finding antibodies for T. cruzi in the blood.Prevention mostly involves eliminating kissing bugs and avoiding their bites. Other preventative efforts include screening blood used for transfusions. A vaccine has not been developed as of 2013. Early infections are treatable with the medication benznidazole or nifurtimox. Medication nearly always results in a cure if given early, but becomes less effective the longer a person has had Chagas disease. When used in chronic disease, medication may delay or prevent the development of end–stage symptoms. Benznidazole and nifurtimox cause temporary side effects in up to 40% of people including skin disorders, brain toxicity, and digestive system irritation.It is estimated that 7 to 8 million people, mostly in Mexico, Central America and South America, have Chagas disease as of 2013. In 2006, Chagas was estimated to result in 12,500 deaths per year. Most people with the disease are poor, and most people with the disease do not realize they are infected. Large-scale population movements have increased the areas where Chagas disease is found and these include many European countries and the United States. These areas have also seen an increase in the years up to 2014. The disease was first described in 1909 by Carlos Chagas after whom it is named. It affects more than 150 other animals.
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