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CHM 3200 - Miami Dade College
CHM 3200 - Miami Dade College

... Course Description: This one-semester course briefly examines the structure, synthesis, nomenclature and reactivity of selected mono- and poly-functional organic compounds. Theories that relate the structure of organic molecules to their chemical reactivity will be presented as a unifying principle. ...
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... have noteworthy impact on network predictions of secondary structure. As a straightforward implementation of this general idea, we have designed the following highly simplified network. The input representation for each amino acid is a 5-bit binary number ordered to reflect one of the following scal ...
A Diels-Alder Synthesis
A Diels-Alder Synthesis

... carbocycle containing two new Carbon-Carbon  bonds. ...
Classification of Halogen Derivatives
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... On the basis of the nature of the carbon to which halogen atom is attached, halogen derivatives are classified as 1°, 2°, 3°, allylic, benzylic, vinylic and aryl derivatives, e.g., ...
Carboxylic Acids Theory Sheet
Carboxylic Acids Theory Sheet

... Carboxylic acids are compounds with the formula of that illustrated in Figure 1 and the general formula R-COOH where R is part of a larger organic molecule e.g.CH3, C2H5, C6H5. To name carboxylic acids you must look at the alkyl chain, take its prefix and add “oic acid” to it. CH3CH2COOH is PROPANOI ...
Single Amino Acids as Additives Modulating CaCO3 Mineralization
Single Amino Acids as Additives Modulating CaCO3 Mineralization

... sulphur group. Proline has a unique structure among the twenty amino acids because of its secondary α-amino group. The cyclic structure of proline shows nonpolar behavior. Serine is a polar amino acid due to the hydroxyl group in the side chain. Valine is an essential amino acid. Together with leuci ...
electron microscopic autoradiographic study of rna synthesis in
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Specialty Chemicals and Food Additives
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Ribosome engineering to promote new crystal forms
Ribosome engineering to promote new crystal forms

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mRNA

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What is Bee Venom?

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Chapter 3 - McGraw Hill Higher Education
Chapter 3 - McGraw Hill Higher Education

Active transport of antibiotics across the outer membrane of gram
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FTIR Spectoscopy of Ca++ DOPED Alq3 OLED Phospor
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... cm-1 by averaging 500 scans at a maximum resolution of 20 C-N Amines. The presence of C-O is revealed by the peak at cm-1 as shown in Fig 2. In case of the polycrystalline 1115.69.The peaks between the range 1000 -400 reveals the samples, scattering due to crystalline is responsible for the bending ...
INTRODUCTION - Open Access Repository of Indian Theses
INTRODUCTION - Open Access Repository of Indian Theses

... existing ones is an important subject of recent research in Organic Chemistry. These are aimed mainly for selectivity, and mild reaction conditions for the synthesis and conversion of bioactive natural products. Several classical synthetic methodologies involve expensive reagents and catalysts, whic ...
An Overview of Carbonyl Compound Chemistry
An Overview of Carbonyl Compound Chemistry

... base as the catalyst. In most cases for esters or derivatives less reactive than esters, for example, hydrolysis of esters, amides, and nitriles, either acids or bases would be added to accelerate the rates of reactions. Also be aware that under these conditions proton transfer(s) can easily occur o ...
Lesson Plan: Synthesis of Isopentyl Acetate
Lesson Plan: Synthesis of Isopentyl Acetate

... Esters are a class of compounds found widely in nature. Low molecular weight esters tend to have characteristic flavors and pleasant odors that are most often associated with essential oils, even though essential oils are a complex mixture. ...
DIGESTIVE PROTEASES OF TWO SPtrCIES OF WASPS OF THE
DIGESTIVE PROTEASES OF TWO SPtrCIES OF WASPS OF THE

... acids.The trypsin in the worker and male wasps was demonstrated. inhibited by 0.4 mM TLCK (Figs. 1(a),1(d)),indicating similarity between the V germanicatrypsin and Mitlptut proteaseuctiuity oJ'Y. maculifrons The trypsin-like activities of V. maculifrons were bovine trypsin. The range of inhibition ...
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Tech Info - Davis Instruments
Tech Info - Davis Instruments

... have to NMR as an analytical tool. While the technical aspects of executing the aldol reaction are not difficult, the analysis of products is challenging since this is frequently a student's first time using NMR instrumentation, interpreting NMR spectra and evaluating the outcome of their synthetic ...
Abstracts - Thieme Verlag
Abstracts - Thieme Verlag

... Hydroformylation of alkenes is a mild and clean method for the functionalization of hydrocarbons and has grown to be among the most important homogeneously catalyzed reactions in industry. It is a 100% atom-economic reaction to prepare aldehydes that are important synthons for organic synthesis, and ...
Case study from Almac
Case study from Almac

... •14C present in the skeleton of all drug molecules. • 14C is Detectable at very low concentrations (scintillation counting) • Long half life means no need for correction for radioactive decay. •3H is also used but is more subject to exchange. ...
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Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
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