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Model Description Sheet
Model Description Sheet

... pathway, small RNAs derived from viruses are used by Ago-2 to slice virus mRNA, protecting the cells from infection. In the miRNA pathway, Ago-2 utilizes naturally occurring miRNA to slice cellular mRNAs to control protein production. Ago-2 works by binding small (~22 nucleotide) regulatory RNAs (si ...
moluceular lab 1
moluceular lab 1

... 1-H-bond : ( Binding between parts of near region and far region from poly-peptide ) 2-Ionic bond : (Binding between free of Amine group at one side of the poly-peptide with free of Carboxyl group on the other side of the poly-peptide 3-di-sulfide bond (-S-S-) :(Binding between two atom of sulfide i ...
Chapter 13
Chapter 13

... - RNA has __________________________ instead of deoxyribose - RNA has the base _______________ instead of Thymine - it still has A, C, & G - ____________will pair with __________ (Uracil is a pyrimidine) ...
DNA AND PROTEIN SYNTHESIS
DNA AND PROTEIN SYNTHESIS

... 2. Ribosome searches for start codon (AUG) 3. tRNA brings correct amino acid (methionine) to the ribosome. ...
File
File

... to the ribosome. The tRNA approaches the ribosome, the anticodon from tRNA binds w/the codon on mRNA. 2. The first codon of mRNA is AUG (start codon for protein synthesis), mRNA slides along the ribosome to the next codon 3. A new tRNA carrying an amino acid will pair w/the mRNA codon 4. When the 1s ...
Translation
Translation

... Translation ● Converts mRNA from transcription into protein (polypeptide) ● Codon- a sequence of 3 RNA nucleotides that code for an amino acid ○ there are 20 amino acids in our body ○ amino acid- monomer of protein ...
Macromolecules
Macromolecules

... The CENTRAL DOGMA OF BIOLOGY! DNA->RNA->Protein ...
第 二 部 分
第 二 部 分

Macromolecules: Proteins and Nucleic Acids
Macromolecules: Proteins and Nucleic Acids

... common amino acids, and they fall into one of four general groups ...
Biochemistry (Macromolecules)
Biochemistry (Macromolecules)

... Proteins (A. K.A. Polypeptides) and Enzymes (Enzymes are a TYPE of protein.) A. These macromolecules make up greater than 50% of an organisms dry weight, called biomass. B. Names usually end with the suffix “lin” (i.e. insulin) for proteins and “ase” for enzymes (i.e. sucrase) C. The monomer “buildi ...
Questions Ch 24
Questions Ch 24

Document
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Protein Synthesis Notes File
Protein Synthesis Notes File

... A. ____________________- the process by which DNA is copied to RNA 1. The enzyme responsible for transcription is ____________________________ 2. RNA polymerase must bind with DNA at a _______________________ a) ___________________- series of repeating nucleotides up stream of the gene to be transcr ...
Protein Structure
Protein Structure

... •The helix is right-handed; it twists in a clockwise direction. •The carbonyl group (-C=O) of each peptide bond extends parallel to the axis of the helix and points directly at the -N-H group of the peptide bond 3 amino acids below it in the helix. •Residues in α-helices typically adopt backbone (φ, ...
Synthetic bile acid derivatives induce apoptosis through a c
Synthetic bile acid derivatives induce apoptosis through a c

... Recently, we have reported that a synthetic derivative of ursodeoxycholic acid (UDCA), HS1183, and those of chenodeoxycholic acid (CDCA), HS-1199 and HS-1200, induced apoptosis in human breast carcinoma cells through a p53-independent pathway. Here, we present that the synthetic bile acid derivative ...
study note 3 33
study note 3 33

... CH3CH2–OH OH ...
NAME
NAME

... 1. Check with the other groups in the class. What other variants of the gene exist? How similar or dissimilar were their DNA sequence? ...
Rice Krispie Treats
Rice Krispie Treats

... 1. Check with the other groups in the class. What other variants of the gene exist? How similar or dissimilar were their DNA sequence? ...
Print Version
Print Version

... as a scaffolding for 20 or more proteins bacterial rRNAs are 16s and 23s while those in eukaryotic ribosomes are 18s and 28s in the Large and Small subunits, respecttively there is also a small 5s rRNA that helps link the subunits e, rRNA is coded by multiple genes in the genome the genes are tandom ...
Proteins
Proteins

BIO II: Biochemistry Test Review Sheet
BIO II: Biochemistry Test Review Sheet

... 11. What bases pair with each other in DNA? In RNA? 12. What type of molecule is shown below? How do you know? ...
Protein Synthesis Notes
Protein Synthesis Notes

... found in DNA. b. Carries instructions to the ribosomes on how to make a specific protein. ...
Classes Until the Harvard Westlake Final
Classes Until the Harvard Westlake Final

... ...
Amino Acids
Amino Acids

... • Best Temp. for enzymes to work ...
Biomolecules at interfaces at atomistic resolution
Biomolecules at interfaces at atomistic resolution

... consisting of an antimicrobial or an amyloid peptide and DNA shall be investigated. The aim is to understand or predict the conformational transition of the peptides upon adsorption to lipid monolayers, the effect of the peptides on lipid structure, and mechanisms of coupling DNA to lipid layers. De ...
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Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
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