novel aspects of carnitine function and metabolism
... MCFA is able to undergo one or two cycles of peroxisomal β-oxidation. This shows that peroxisomes may have a more prominent role than earlier assumed in the oxidation of straight-chain fatty acids which are not typically metabolized in this cellular compartment, potentially acting as a compensatory ...
... MCFA is able to undergo one or two cycles of peroxisomal β-oxidation. This shows that peroxisomes may have a more prominent role than earlier assumed in the oxidation of straight-chain fatty acids which are not typically metabolized in this cellular compartment, potentially acting as a compensatory ...
Nicotinamide adenine dinucleotide, a metabolic regulator of
... increased cycling through the salvage pathway does not affect the overall steady-state NAD level or NAD : NADH ratio. It has been suggested that the salvage www.current-opinion.com ...
... increased cycling through the salvage pathway does not affect the overall steady-state NAD level or NAD : NADH ratio. It has been suggested that the salvage www.current-opinion.com ...
Multiple sequence alignment for phylogenetic purposes
... (and therefore perversely fascinating) because I have always believed that there should be as much biology in a sequence alignment as there is mathematics and computing. This review is about just that idea, and is dedicated to putting biology back into the sequence alignment procedures used as part ...
... (and therefore perversely fascinating) because I have always believed that there should be as much biology in a sequence alignment as there is mathematics and computing. This review is about just that idea, and is dedicated to putting biology back into the sequence alignment procedures used as part ...
Technical Brief
... The first paper from Cicely Williams, originally published in 1933, remained understandably circumspect regarding the origin of the disease. 6 It noted simply that it is frequently associated with a monotonous maize-based diet and concludes with the following statement: “Breast milk is probably defi ...
... The first paper from Cicely Williams, originally published in 1933, remained understandably circumspect regarding the origin of the disease. 6 It noted simply that it is frequently associated with a monotonous maize-based diet and concludes with the following statement: “Breast milk is probably defi ...
Understanding the Regulation of Metabolic Enzyme Acetylation in E
... Currently, there are two proposed mechanisms by which Nε-lysine acetylation is thought to occur: 1) enzymatic regulation of Nε-lysine acetylation and 2) spontaneous acetylation of lysines. Enzymatic regulation of Nε-lysine acetylation is controlled by two groups of proteins: lysine acetyltransferase ...
... Currently, there are two proposed mechanisms by which Nε-lysine acetylation is thought to occur: 1) enzymatic regulation of Nε-lysine acetylation and 2) spontaneous acetylation of lysines. Enzymatic regulation of Nε-lysine acetylation is controlled by two groups of proteins: lysine acetyltransferase ...
The Bacterial Toxin RelE Displays Codon
... of protein synthesis by RelE in vivo. We have found that although RelE does not degrade free RNA, it cleaves mRNA in the ribosomal A site with high codon specificity. Among stop codons UAG is cleaved with fast, UAA intermediate and UGA slow rate, while UCG and CAG are cleaved most rapidly among sens ...
... of protein synthesis by RelE in vivo. We have found that although RelE does not degrade free RNA, it cleaves mRNA in the ribosomal A site with high codon specificity. Among stop codons UAG is cleaved with fast, UAA intermediate and UGA slow rate, while UCG and CAG are cleaved most rapidly among sens ...
Regulation of Phenylalanine and Tyrosine
... were assayed as described in Methods. The Ki value of L-phenylalanine in the chorismate mutase reaction was determined at 0.9 mM-chorismate. The Ki value of L-phenylalanine in the prephenate dehydratase I reaction as well as the K, value of L-tyrosine were each determined at 0 . 3 4 m ~ prephenate. ...
... were assayed as described in Methods. The Ki value of L-phenylalanine in the chorismate mutase reaction was determined at 0.9 mM-chorismate. The Ki value of L-phenylalanine in the prephenate dehydratase I reaction as well as the K, value of L-tyrosine were each determined at 0 . 3 4 m ~ prephenate. ...
The P53 pathway and metabolism: implications in tissue
... Changes associated with cellular senescence: Permanent cell cycle arrest Flat morphology, vacuolized cytoplasm, condensed chromatin (SAHF) SA b-Gal positive (lysosomal changes) Senescent markers (p16, p15, ARF, PML, uPAI1) Secretory phenotype (pro-inflammatory chemokines, IGFBP,…) Changes in metabol ...
... Changes associated with cellular senescence: Permanent cell cycle arrest Flat morphology, vacuolized cytoplasm, condensed chromatin (SAHF) SA b-Gal positive (lysosomal changes) Senescent markers (p16, p15, ARF, PML, uPAI1) Secretory phenotype (pro-inflammatory chemokines, IGFBP,…) Changes in metabol ...
hhmi resource for new ap bio curriculum
... wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. ...
... wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. ...
animal nutrition - e
... P. McDonald R. A. Edwards J. F. D. Greenhalgh C. A. Morgan L. A. Sinclair R. G. Wilkinson Animal Nutrition is a core text for undergraduates in Animal Science, Veterinary Science, Agriculture, Biology and Biochemistry studying this subject. It also provides a standard reference text for agricultural ...
... P. McDonald R. A. Edwards J. F. D. Greenhalgh C. A. Morgan L. A. Sinclair R. G. Wilkinson Animal Nutrition is a core text for undergraduates in Animal Science, Veterinary Science, Agriculture, Biology and Biochemistry studying this subject. It also provides a standard reference text for agricultural ...
Localization and nucleotide specificity of Blastocystis succinyl‐CoA
... E + succinyl-COA + Pi ↔ E − succinyl-PO3 + CoA ...
... E + succinyl-COA + Pi ↔ E − succinyl-PO3 + CoA ...
Eram_SeyedMohammad - UWSpace
... neapolitana, and P. furiosus) had the highest AHAS activity at nearly neutral pH, but the ones without ilv operon still had some residual AHAS activity mostly at a higher pH value (pH 10.5). It was shown that the cell-free extracts of T. maritima can catalyze the non-oxidative decarboxylation of the ...
... neapolitana, and P. furiosus) had the highest AHAS activity at nearly neutral pH, but the ones without ilv operon still had some residual AHAS activity mostly at a higher pH value (pH 10.5). It was shown that the cell-free extracts of T. maritima can catalyze the non-oxidative decarboxylation of the ...
Cytogenetic Analysis Shows that the Unusually Large Chromosome
... strain was variable. Evidently, the W chromosome of the TWPB strain is attached to another chromosome. The composition of the W chromosome, the second chromosome fragment, and the fifth chromosome was studied through linkage analysis for these three chromosomes. We used two strains derived from the ...
... strain was variable. Evidently, the W chromosome of the TWPB strain is attached to another chromosome. The composition of the W chromosome, the second chromosome fragment, and the fifth chromosome was studied through linkage analysis for these three chromosomes. We used two strains derived from the ...
Sample question set 1 biology
... What specific biological process is believed to have produced most of the diatomic oxygen in the Earth’s atmosphere? ANSWER: PHOTOSYNTHESIS BONUS 15) BIOLOGY Short Answer In photosynthesis II (read as: two), what is light energy most notably used to initially accomplish? ANSWER: SPLITTING OF WATER T ...
... What specific biological process is believed to have produced most of the diatomic oxygen in the Earth’s atmosphere? ANSWER: PHOTOSYNTHESIS BONUS 15) BIOLOGY Short Answer In photosynthesis II (read as: two), what is light energy most notably used to initially accomplish? ANSWER: SPLITTING OF WATER T ...
Biochemistry of coenzyme B12‐dependent glycerol and diol
... homologs is to encase diol dehydratase within a polyhedral shell. Thus far, four homologs of carboxysome shell protein genes have been identi¢ed in the pdu operon [40]. Electron microscopy showed that S. enterica forms polyhedral bodies during growth on 1,2-propanediol, and immuno-electron microscop ...
... homologs is to encase diol dehydratase within a polyhedral shell. Thus far, four homologs of carboxysome shell protein genes have been identi¢ed in the pdu operon [40]. Electron microscopy showed that S. enterica forms polyhedral bodies during growth on 1,2-propanediol, and immuno-electron microscop ...
DETERMINATION AND POLARITY
... the ovary and egl mRNA and protein localize to the developing oocyte very early in oogenesis. Three lines of evidence show that egl interacts with BicaudalD(BicD), another gene required for oocyte determination. First, the Egl and BicD proteins colocalize within the egg and this localization require ...
... the ovary and egl mRNA and protein localize to the developing oocyte very early in oogenesis. Three lines of evidence show that egl interacts with BicaudalD(BicD), another gene required for oocyte determination. First, the Egl and BicD proteins colocalize within the egg and this localization require ...
Antimicrobial peptides
... diminish the use of antibiotics in aquaculture, by replacing a part of the latter. Due to the harmlessness of AMPs, their use Would bene?t brand image, but also health of the animals to be treated, customers and the environment, With no fear to favour the emergent evolution of antibiotic-resistant s ...
... diminish the use of antibiotics in aquaculture, by replacing a part of the latter. Due to the harmlessness of AMPs, their use Would bene?t brand image, but also health of the animals to be treated, customers and the environment, With no fear to favour the emergent evolution of antibiotic-resistant s ...
Emerging role of Nrf2 - Discovery
... been disrupted (Nrf2-KO) [35]. This difference is particularly striking upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same condition ...
... been disrupted (Nrf2-KO) [35]. This difference is particularly striking upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same condition ...
NF1 Gene Test Review - The Friedman Lab at UBC
... disease, central nervous system (CNS) tumors, or malignant peripheral nerve sheath tumors. NF1 is characterized by extreme clinical variability, not only among unrelated individuals and among affected individuals within a single family but also even within a single person at different times in life. ...
... disease, central nervous system (CNS) tumors, or malignant peripheral nerve sheath tumors. NF1 is characterized by extreme clinical variability, not only among unrelated individuals and among affected individuals within a single family but also even within a single person at different times in life. ...
The metabolic basis of Candida albicans
... The morphogenesis of C. albicans is predominately determined by environmental signaling. The yeast-to-filamentous transition can be triggered by serum, proline, N-acetylglucosamine, different carbon sources, and other cues as summarized in Table 1. However, there is a lack of understanding about how ...
... The morphogenesis of C. albicans is predominately determined by environmental signaling. The yeast-to-filamentous transition can be triggered by serum, proline, N-acetylglucosamine, different carbon sources, and other cues as summarized in Table 1. However, there is a lack of understanding about how ...
Title Biotin Biosynthesis in Microorganisms (Commemoration Issue
... INTRODUCTION Biotin, or vitamin H, can be synthesized by a great number of microorganisms, while some organisms which cannot synthesize biotin require it for growth. It is also well known that biotin widely distributes in plant and animal tissues. Main biochemical function of biotin is as the cofact ...
... INTRODUCTION Biotin, or vitamin H, can be synthesized by a great number of microorganisms, while some organisms which cannot synthesize biotin require it for growth. It is also well known that biotin widely distributes in plant and animal tissues. Main biochemical function of biotin is as the cofact ...
The Handbook of Redox Biochemistry- ESA, Inc.
... Oxygen is toxic to aerobic (and anaerobic) organisms, yet paradoxically oxygen is essential for their survival. Today terrestrial aerobes (both animals and plants) have successfully adapted to live in an atmosphere composed of approximately 21% oxygen and can survive minor fluctuations in the level ...
... Oxygen is toxic to aerobic (and anaerobic) organisms, yet paradoxically oxygen is essential for their survival. Today terrestrial aerobes (both animals and plants) have successfully adapted to live in an atmosphere composed of approximately 21% oxygen and can survive minor fluctuations in the level ...
Full-Text PDF
... generation of metabolic energy and hence in the survival of most cells. The TCA cycle intermediates fuel this mitochondrial metabolism. However, mitochondria also are the site at which a considerable amount of highly reactive oxygen radicals (superoxide, hydrogen peroxide, and hydroxyl radical) is g ...
... generation of metabolic energy and hence in the survival of most cells. The TCA cycle intermediates fuel this mitochondrial metabolism. However, mitochondria also are the site at which a considerable amount of highly reactive oxygen radicals (superoxide, hydrogen peroxide, and hydroxyl radical) is g ...
Serotype IX, a Proposed New Streptococcus agalactiae
... Streptococcus agalactiae, also known as group B streptococcus (GBS), is a pathogen of newborn infants in particular but also a cause of bacteremia in parturient women, elderly people, and immunocompromised patients (11). The current classification of GBS is based on the capsular phenotype (1). Curre ...
... Streptococcus agalactiae, also known as group B streptococcus (GBS), is a pathogen of newborn infants in particular but also a cause of bacteremia in parturient women, elderly people, and immunocompromised patients (11). The current classification of GBS is based on the capsular phenotype (1). Curre ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.