as a PDF
... factor to recognize UAA efficiently (Klobutcher and Farabaugh, 2002). Future work will determine if these ⫹1 frameshifting events have any regulatory function and whether other mRNA elements are involved. Two other examples of ⫹ 1 frameshifting in eukaryotes warrant mention. The ABP140 gene of S. ce ...
... factor to recognize UAA efficiently (Klobutcher and Farabaugh, 2002). Future work will determine if these ⫹1 frameshifting events have any regulatory function and whether other mRNA elements are involved. Two other examples of ⫹ 1 frameshifting in eukaryotes warrant mention. The ABP140 gene of S. ce ...
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics
... 313 residue located in this region is phosphorylated by cyclin dependent kinases (CDKs), which might prevent USP1 degradation in mitosis (Cotto-Rios et al., 2011b). On the other hand, UV damage causes USP1 autocleavage at an internal diglycine motif (Gly-Gly) located in the C-terminal end of the pro ...
... 313 residue located in this region is phosphorylated by cyclin dependent kinases (CDKs), which might prevent USP1 degradation in mitosis (Cotto-Rios et al., 2011b). On the other hand, UV damage causes USP1 autocleavage at an internal diglycine motif (Gly-Gly) located in the C-terminal end of the pro ...
REVIEW ARTICLE Regulation of Expression of the Integrated
... RNA indicate that one provirus is transcriptionally active while the other is apparently transcriptionally inactive. DNase sensitivity studies of the chromatin carrying the viral sequence support this conclusion (Yamamoto et al., 1980). The cellular sequences adjacent to these proviruses have been i ...
... RNA indicate that one provirus is transcriptionally active while the other is apparently transcriptionally inactive. DNase sensitivity studies of the chromatin carrying the viral sequence support this conclusion (Yamamoto et al., 1980). The cellular sequences adjacent to these proviruses have been i ...
Analyzing the Changes in DNA Flexibility Due to Base Modifications
... When the water and ions are placed, they are placed randomly, and there may be high energy clashes that would apply very large forces at the beginning of any subsequent simulations. The DNA double helix is fairly fragile, and it is possible that hydrogen bonds could be broken early on in the simulat ...
... When the water and ions are placed, they are placed randomly, and there may be high energy clashes that would apply very large forces at the beginning of any subsequent simulations. The DNA double helix is fairly fragile, and it is possible that hydrogen bonds could be broken early on in the simulat ...
Physical mapping shows that the unstable oxytetracycline gene
... important antibiotic oxytetracycline (OTC) in Streptomyces rimosus lie in a cluster of about 30 kb in size flanked by two resistance genes. This pattern is seen both in the ‘ Pfizer strain ’ (S. rimosus M4018 lineage ; Butler et al., 1989) and in the ‘ Zagreb strain ’ (S. rimosus R6 lineage ; Peric! ...
... important antibiotic oxytetracycline (OTC) in Streptomyces rimosus lie in a cluster of about 30 kb in size flanked by two resistance genes. This pattern is seen both in the ‘ Pfizer strain ’ (S. rimosus M4018 lineage ; Butler et al., 1989) and in the ‘ Zagreb strain ’ (S. rimosus R6 lineage ; Peric! ...
Fractals are observed in nature
... that different organisms exhibited different patterns in the images. As mentioned by Deschavanne et al. (1999), a closer look at the Fig.3a reveals two major features of the DNA sequence. First, the empty patches indicate that the areas which have GC in their addresses have notably low density. This ...
... that different organisms exhibited different patterns in the images. As mentioned by Deschavanne et al. (1999), a closer look at the Fig.3a reveals two major features of the DNA sequence. First, the empty patches indicate that the areas which have GC in their addresses have notably low density. This ...
Amino Acid Requirements for Formation of the
... procedure was doubtful since the curves varied somewhat in form and it was difficult to decide the incubation times required to produce cultures of strictly comparable physiological age. Forunately, however, the ' age of culture' effect proved to be very much less marked on simple media. Both the ba ...
... procedure was doubtful since the curves varied somewhat in form and it was difficult to decide the incubation times required to produce cultures of strictly comparable physiological age. Forunately, however, the ' age of culture' effect proved to be very much less marked on simple media. Both the ba ...
Oxypred: Prediction and Classification of Oxygen-Binding
... Oxygen-binding proteins are widely present in eukaryotes ranging from non-vertebrates to humans (1 ). Moreover, these proteins have also been reported to be present in many prokaryotes and protozoans (2 ). The occurrence of oxygen-binding proteins in all kingdoms of organisms, though not in all orga ...
... Oxygen-binding proteins are widely present in eukaryotes ranging from non-vertebrates to humans (1 ). Moreover, these proteins have also been reported to be present in many prokaryotes and protozoans (2 ). The occurrence of oxygen-binding proteins in all kingdoms of organisms, though not in all orga ...
Functional monopolar spindles caused by
... same happens with CMFs, even using very loose criteria to define a figure as a circle in doubly mutant brains. Since the effect of asp is thought to be spindlespecific, the absence of CMFs in mgr asp brains shows that a functional spindle is needed for these figures to be formed and maintained. Defe ...
... same happens with CMFs, even using very loose criteria to define a figure as a circle in doubly mutant brains. Since the effect of asp is thought to be spindlespecific, the absence of CMFs in mgr asp brains shows that a functional spindle is needed for these figures to be formed and maintained. Defe ...
Discussions of the “Ridge Gene”
... Congress in Texas. Nikki summarized the results of her doctoral thesis work on genetics of the ridge and dermoid sinus, some of which was published in a recent article in the prestigious journal Nature Genetics. 2 I have summarized this work in a previous article in The Ridgeback,3 and I refer the r ...
... Congress in Texas. Nikki summarized the results of her doctoral thesis work on genetics of the ridge and dermoid sinus, some of which was published in a recent article in the prestigious journal Nature Genetics. 2 I have summarized this work in a previous article in The Ridgeback,3 and I refer the r ...
A rough guide to Drosophila mating schemes (light version 2.1) 1
... fly variants are the bread-and-butter of fly research, providing the tools by which genes are manipulated or visualised in action in order to investigate their function. The art of Drosophila genetics is to use these tools, not only in isolation but often combined in the same flies. This combinatori ...
... fly variants are the bread-and-butter of fly research, providing the tools by which genes are manipulated or visualised in action in order to investigate their function. The art of Drosophila genetics is to use these tools, not only in isolation but often combined in the same flies. This combinatori ...
Developmental and Genetic Diseases
... Motif–A DNA-sequence pattern within a gene that, because of its similarity to sequences in other known genes, suggests a possible function of the gene, its protein product, or both. Multifactorial–Caused by the interaction of multiple genetic and environmental factors. Nonconservative mutation–A cha ...
... Motif–A DNA-sequence pattern within a gene that, because of its similarity to sequences in other known genes, suggests a possible function of the gene, its protein product, or both. Multifactorial–Caused by the interaction of multiple genetic and environmental factors. Nonconservative mutation–A cha ...
Additional content in Biology based on Revised syllabus.
... certain genes present in the X chromosome. It occurs in about 8 per cent of males and only about 0.4 per cent of females. This is because the genes that lead to red–green colour blindness are on the X chromosome. Males have only one X chromosome and females have two. The son of a woman who carries t ...
... certain genes present in the X chromosome. It occurs in about 8 per cent of males and only about 0.4 per cent of females. This is because the genes that lead to red–green colour blindness are on the X chromosome. Males have only one X chromosome and females have two. The son of a woman who carries t ...
A novel species of thermoacidophilic archaeon, Sulfolobus
... 165 rRNA sequencing. In order to avoid amplifying pseudogenes (or non-functional genes) (Chaw et al., 1995), total RNA was extracted from fresh cells using the modified method of Raha et al. (1990), in which genomic DNA was removed by DNase I treatment (Boehringer Mannheim). The method of Goodman & ...
... 165 rRNA sequencing. In order to avoid amplifying pseudogenes (or non-functional genes) (Chaw et al., 1995), total RNA was extracted from fresh cells using the modified method of Raha et al. (1990), in which genomic DNA was removed by DNase I treatment (Boehringer Mannheim). The method of Goodman & ...
Genetic Inversion: Relationships Among Species
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
Active Transport of Amino Acids by Membrane
... The vesicle preparation described here was active primarily with the nonphysiological electron donors, ascorbate-TMPI) or ascorbate-PMS. Relatively little stimulation of transport was observed with any of the potentially physiological electron donors tested. The reason for this is not known. Effecti ...
... The vesicle preparation described here was active primarily with the nonphysiological electron donors, ascorbate-TMPI) or ascorbate-PMS. Relatively little stimulation of transport was observed with any of the potentially physiological electron donors tested. The reason for this is not known. Effecti ...
PTC_241Lecture005Cells
... that we call promoter regions and those promoter regions have to bind transcription factors in order for transcription to take place. So protein synthesis just doesn’t happen willy nilly. It’s only activated when certain kind of factors bind to the chromosome and start transcription. So it’s a swit ...
... that we call promoter regions and those promoter regions have to bind transcription factors in order for transcription to take place. So protein synthesis just doesn’t happen willy nilly. It’s only activated when certain kind of factors bind to the chromosome and start transcription. So it’s a swit ...
Lecture Notes BS1090
... cAMP phosphodiesterase (588) which hydrolyzes the 3’ phosphate bond of cAMP and breaks down the second messenger into an inactive product (AMP). The activity of this enzyme also acts as a switch and a timer that acts to terminate the signal. This enzyme may also be activated by the hormone, resulti ...
... cAMP phosphodiesterase (588) which hydrolyzes the 3’ phosphate bond of cAMP and breaks down the second messenger into an inactive product (AMP). The activity of this enzyme also acts as a switch and a timer that acts to terminate the signal. This enzyme may also be activated by the hormone, resulti ...
Poon, Andy: Predicting Phosphorylation: A critique of the NetPhos program and potential alternatives
... phosphates because they all contain a hydroxyl group in their side chains which are deprotonated at physiological pH, such that the oxyanion can act as a nucleophile to attack a phosphate from ATP. However, not all serines (S), threonines (T), and tyrosines (Y) are susceptible to phosphorylation. Th ...
... phosphates because they all contain a hydroxyl group in their side chains which are deprotonated at physiological pH, such that the oxyanion can act as a nucleophile to attack a phosphate from ATP. However, not all serines (S), threonines (T), and tyrosines (Y) are susceptible to phosphorylation. Th ...
Conservation and relative importance of residues across protein
... fully buried in the interface, whereas the latter only contains atoms that retain partial accessibility (24, 25). The core possesses more hydrophobic residues and has a composition that is distinct from the rim or the rest of the protein surface. With the division into core and rim residues one can ...
... fully buried in the interface, whereas the latter only contains atoms that retain partial accessibility (24, 25). The core possesses more hydrophobic residues and has a composition that is distinct from the rim or the rest of the protein surface. With the division into core and rim residues one can ...
Polyacrylamide Gel Electrophoresis Analysis of Ribosomal Protein
... niveoalba) (Fig. 1B through D). These results, together with the results of a DNA-DNA pairing test (18), suggest that these three species might be combined into a single species. The extensive similarities were especially impressive for Microtetraspora roseoviolacea, Microtetraspora salmonea, and Mi ...
... niveoalba) (Fig. 1B through D). These results, together with the results of a DNA-DNA pairing test (18), suggest that these three species might be combined into a single species. The extensive similarities were especially impressive for Microtetraspora roseoviolacea, Microtetraspora salmonea, and Mi ...
Conservation, relocation and duplication in genome evolution
... constraints than nonessential genes [27] includes hidden assumptions about effective population size. In any population, the fate of a new mutation is determined by the relative strength of natural selection (proportional to the selection coefficient) as against the effects of random genetic drift ( ...
... constraints than nonessential genes [27] includes hidden assumptions about effective population size. In any population, the fate of a new mutation is determined by the relative strength of natural selection (proportional to the selection coefficient) as against the effects of random genetic drift ( ...
Regents Biology
... Immune System Antibodies bind to specific foreign particles, such as viruses and bacteria, to help protect the body. ...
... Immune System Antibodies bind to specific foreign particles, such as viruses and bacteria, to help protect the body. ...
and paralogue-specific functions of acyl-CoA
... mice has been reported to cause pre-implantation embryonic lethality in mice [19], consistent with an essential function to support cellular survival and growth in human cell lines [20] and in Trypanosoma brucei [21]. Depletion of Acb1 (S. cerevisiae ACBP1) in S. cerevisiae causes severe growth reta ...
... mice has been reported to cause pre-implantation embryonic lethality in mice [19], consistent with an essential function to support cellular survival and growth in human cell lines [20] and in Trypanosoma brucei [21]. Depletion of Acb1 (S. cerevisiae ACBP1) in S. cerevisiae causes severe growth reta ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.