
BMC Cancer TGFBR1*6A colorectal cancer in a Spanish population: a case-control study
... exon 1 and germline allele-specific expression were also conducted to obtain further information on the contribution of the TGFBR1*6A allele to CRC susceptibility. Results: There was no statistically significant association between the TGFBR1*6A allele and CRC (p > 0.05). The OR was 1.147 (95% CI: 0 ...
... exon 1 and germline allele-specific expression were also conducted to obtain further information on the contribution of the TGFBR1*6A allele to CRC susceptibility. Results: There was no statistically significant association between the TGFBR1*6A allele and CRC (p > 0.05). The OR was 1.147 (95% CI: 0 ...
Gene clusters for β-lactam antibiotics and control of their expression
... The cefG gene contains two introns and is linked to cefEF, but in the opposite orientation. Bioinformatic analysis of cefG revealed 55% identical residues with the met2 genes of Aspergillus fumigatus and Ascobolus immersus. The met2 genes encode O-acetyl homoserine acetyl transferase activity involv ...
... The cefG gene contains two introns and is linked to cefEF, but in the opposite orientation. Bioinformatic analysis of cefG revealed 55% identical residues with the met2 genes of Aspergillus fumigatus and Ascobolus immersus. The met2 genes encode O-acetyl homoserine acetyl transferase activity involv ...
Large Scale SNP Scanning on Human Chromosome Y and DNA
... Over the past 15 years, DNA polymorphisms have been widely used to reconstruct human evolutionary history. Mitochondrial DNA was originally used for this purpose, because the high mutation rate produced numerous polymorphisms and the absence of recombination facilitated their interpretation. Thirty- ...
... Over the past 15 years, DNA polymorphisms have been widely used to reconstruct human evolutionary history. Mitochondrial DNA was originally used for this purpose, because the high mutation rate produced numerous polymorphisms and the absence of recombination facilitated their interpretation. Thirty- ...
video slide - Mrs. H-D
... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
NOTE Preliminary organic compound analysis of microparticles returned from
... acids was reported in Antarctic LL5 chondrites (Botta et al., 2008), the detected amino acids may be contaminants from Antarctic ice. Or carbonaceous particles with amino acids may be incorporated into the meteorite parent body after thermal metamorphism. The surface of Itokawa may not be a good pla ...
... acids was reported in Antarctic LL5 chondrites (Botta et al., 2008), the detected amino acids may be contaminants from Antarctic ice. Or carbonaceous particles with amino acids may be incorporated into the meteorite parent body after thermal metamorphism. The surface of Itokawa may not be a good pla ...
Figure 5 - GEP Community Server
... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
Steroid/Thyroid Receptor-like Proteins with
... (M, 94,000). This suggests a mutation in the hormone-binding domain (45-47). The r~ phenotype may in some cells also arise from lack of expression of receptor with no gene product or specific mRNA detectable (48). Whatever the cause of the r" phenotype may be, this phenomenon is not due to gross DNA ...
... (M, 94,000). This suggests a mutation in the hormone-binding domain (45-47). The r~ phenotype may in some cells also arise from lack of expression of receptor with no gene product or specific mRNA detectable (48). Whatever the cause of the r" phenotype may be, this phenomenon is not due to gross DNA ...
module 5: translation - GEP Community Server
... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
Functional genomics identifies a Myb domain– containing protein
... The aforementioned results suggest that KNL-2 physically associates with CeCENP-A nucleosomes to facilitate their loading and function. To test this idea, we isolated embryonic interphase nuclei from a strain expressing GFP–KNL-2, sonicated the chromatin to 500–1,500-bp fragments, and immunoprecipit ...
... The aforementioned results suggest that KNL-2 physically associates with CeCENP-A nucleosomes to facilitate their loading and function. To test this idea, we isolated embryonic interphase nuclei from a strain expressing GFP–KNL-2, sonicated the chromatin to 500–1,500-bp fragments, and immunoprecipit ...
Transgenic Tobacco Plants Expressing the Drosophila
... not express the transgene produced an abnormal phenotype, but we also could not detect any significant abnormalities in one of the expressing plants, line 14 (Table 2). In agreement with our previous observations (Table 1), we conclude that expression of the PCcd construct is necessary but not alway ...
... not express the transgene produced an abnormal phenotype, but we also could not detect any significant abnormalities in one of the expressing plants, line 14 (Table 2). In agreement with our previous observations (Table 1), we conclude that expression of the PCcd construct is necessary but not alway ...
msb145697-sup-0001-Supp_Info
... glutamate dehydrogenase (GDH, purple diamond, encoded by gdhA) to form glutamate (glu), which subsequently trans-aminates (green diamond) one of many alpha-keto acids (light blue oval) to form amino acids (yellow oval), regenerating akg in the process. In pathway B, the overall process is the same e ...
... glutamate dehydrogenase (GDH, purple diamond, encoded by gdhA) to form glutamate (glu), which subsequently trans-aminates (green diamond) one of many alpha-keto acids (light blue oval) to form amino acids (yellow oval), regenerating akg in the process. In pathway B, the overall process is the same e ...
Conformational flexibility may explain multiple cellular roles of PEST
... property of the protein structural behavior and is attributed to various biochemical activities. Although the existence of small- and large-scale protein motions has been well reported, their roles in biological processes need to be explored at a wider scale. Nevertheless, several types of atomic mo ...
... property of the protein structural behavior and is attributed to various biochemical activities. Although the existence of small- and large-scale protein motions has been well reported, their roles in biological processes need to be explored at a wider scale. Nevertheless, several types of atomic mo ...
Gene Section SOX10 (SRY (sex determining region Y)-box 10)
... family possess a high-mobility-group (HMG) domain with three alpha-helical regions and close similarity to the one found in the male sex determining factor SRY. SOX10 functions as transcription factor and structural protein in chromatin. SOX9 and SOX8 are its closest relatives among human SOX protei ...
... family possess a high-mobility-group (HMG) domain with three alpha-helical regions and close similarity to the one found in the male sex determining factor SRY. SOX10 functions as transcription factor and structural protein in chromatin. SOX9 and SOX8 are its closest relatives among human SOX protei ...
Chapter 17 End?of?Chapter Problems Key
... The first step is collection of materials in curbside recycling bins or central collection areas. The next step is sorting. The recycling symbols found on objects made of polymers tell the recycling companies what type of polymer was used in the object’s construction. The last step is the removal of ...
... The first step is collection of materials in curbside recycling bins or central collection areas. The next step is sorting. The recycling symbols found on objects made of polymers tell the recycling companies what type of polymer was used in the object’s construction. The last step is the removal of ...
Proteins - MATERI KULIAH PANGAN
... Electrophoresis is usually performed on serum rather than plasma since the fibrinogen present in plasma produces a band in the β region that might be mistaken for a paraprotein. M. Zaharna Clin. Chem. 2009 ...
... Electrophoresis is usually performed on serum rather than plasma since the fibrinogen present in plasma produces a band in the β region that might be mistaken for a paraprotein. M. Zaharna Clin. Chem. 2009 ...
Analysis of Toxoplasma gondii Repeat Region 529 bp (NCBI Acc
... The current methods for the diagnosis of toxoplasmosis have given dismayingly poor results in such patients and, therefore, there is a need for more sensitive procedures for the early diagnosis of Toxoplasma gondii in body fluids or biopsy tissues (Savva and Holliman, 1990). The diagnosis of toxopla ...
... The current methods for the diagnosis of toxoplasmosis have given dismayingly poor results in such patients and, therefore, there is a need for more sensitive procedures for the early diagnosis of Toxoplasma gondii in body fluids or biopsy tissues (Savva and Holliman, 1990). The diagnosis of toxopla ...
Effect of
... larvae require 53% crude dietary protein (Fiogbé and Kestemont, 1995). The difference in goldfish protein requirements between these two studies may be attributed to the age of the fish. Other factors also affect dietary protein requirements, including the dietary protein to energy ratio, the essent ...
... larvae require 53% crude dietary protein (Fiogbé and Kestemont, 1995). The difference in goldfish protein requirements between these two studies may be attributed to the age of the fish. Other factors also affect dietary protein requirements, including the dietary protein to energy ratio, the essent ...
FEATURE SELECTION = GENE SELECTION
... • A common disadvantage of filter approaches is that – they ignore the interaction with the classifier (the search in the gene subset space is separated from the search in the hypothesis space), and – that most proposed techniques are univariate. This means that each gene is considered separately, t ...
... • A common disadvantage of filter approaches is that – they ignore the interaction with the classifier (the search in the gene subset space is separated from the search in the hypothesis space), and – that most proposed techniques are univariate. This means that each gene is considered separately, t ...
An hierarchical artificial neural network system for the classification
... However, these algorithms focus on the localization of transmembrane segments in known integral membrane proteins and are not suited to the discrimination of membrane proteins from non-membrane proteins. Recently, we have published the PRED-TMR method in an attempt to improve the fine localization o ...
... However, these algorithms focus on the localization of transmembrane segments in known integral membrane proteins and are not suited to the discrimination of membrane proteins from non-membrane proteins. Recently, we have published the PRED-TMR method in an attempt to improve the fine localization o ...
Meiosis II
... • Once movement is complete, each pole has a haploid number of chromosomes. • In most cases, cytokinesis occurs at the same time as telophase I. • At the end of telophase I and cytokinesis, two daughter cells are produced, each with one half the number of chromosomes of the original parent cell. ...
... • Once movement is complete, each pole has a haploid number of chromosomes. • In most cases, cytokinesis occurs at the same time as telophase I. • At the end of telophase I and cytokinesis, two daughter cells are produced, each with one half the number of chromosomes of the original parent cell. ...
Appendix I
... published), “something is missing” is the call. So it can only be expected that young naïve researchers will come along and try to think outside the box of conventional AI. I am one of those and my ingredient to add to the recipe that is artificial intelligence is of a semiphilosophical/semi-biologi ...
... published), “something is missing” is the call. So it can only be expected that young naïve researchers will come along and try to think outside the box of conventional AI. I am one of those and my ingredient to add to the recipe that is artificial intelligence is of a semiphilosophical/semi-biologi ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.