Population genetics
... genetics, descriptions can be made of the frequencies of various genotypes and alleles in populations, and/or the levels of genetic variation can be determined. A population is a collection of organisms of a single species the individuals of which interact with each other in some way. So, a species ...
... genetics, descriptions can be made of the frequencies of various genotypes and alleles in populations, and/or the levels of genetic variation can be determined. A population is a collection of organisms of a single species the individuals of which interact with each other in some way. So, a species ...
1 X chromosome crossover formation and genome stability in
... known as crossing over. Homologous recombination is employed in the repair of both genotoxic lesions and programmed DSBs and many of the core DNA repair proteins function in both processes. In addition, DNA repair efficiency and crossover distribution are both influenced by local and global differen ...
... known as crossing over. Homologous recombination is employed in the repair of both genotoxic lesions and programmed DSBs and many of the core DNA repair proteins function in both processes. In addition, DNA repair efficiency and crossover distribution are both influenced by local and global differen ...
Speciation genes in plants - Oxford Academic
... † Background Analyses of speciation genes – genes that contribute to the cessation of gene flow between populations – can offer clues regarding the ecological settings, evolutionary forces and molecular mechanisms that drive the divergence of populations and species. This review discusses the identi ...
... † Background Analyses of speciation genes – genes that contribute to the cessation of gene flow between populations – can offer clues regarding the ecological settings, evolutionary forces and molecular mechanisms that drive the divergence of populations and species. This review discusses the identi ...
Characterization of melanocyte stimulating hormone
... pheomelanins (4). It has also been shown that relatively minor differences in melanin quality or content can have dramatic effects on visible hair colour. Ultrastructurally, eumelanin synthesis is restricted to discrete organelles termed eumelanosomes, while the pheomelanins are synthesized in pheom ...
... pheomelanins (4). It has also been shown that relatively minor differences in melanin quality or content can have dramatic effects on visible hair colour. Ultrastructurally, eumelanin synthesis is restricted to discrete organelles termed eumelanosomes, while the pheomelanins are synthesized in pheom ...
Tandem duplications and the limits of natural
... neutral SNPs from 8-30 bp of short introns to search for signals of reduced diversity consistent with selection acting on tandem duplications. These tandem duplications are polymorphic and represent putative sweeps in progress and such comparisons to within-genome controls of neutral SNPs offer grea ...
... neutral SNPs from 8-30 bp of short introns to search for signals of reduced diversity consistent with selection acting on tandem duplications. These tandem duplications are polymorphic and represent putative sweeps in progress and such comparisons to within-genome controls of neutral SNPs offer grea ...
Genes for control of form and
... 2006; Berleth et al., 2007; DeSmet & Jurgens, 2007; Kerr & Bennett, 2007). Below we summarize the genes that are strong modifiers of plant form and shape. Polar auxin transport Because auxin acts in a concentrationdependent manner and auxin gradients serve as positional signals, plants have develope ...
... 2006; Berleth et al., 2007; DeSmet & Jurgens, 2007; Kerr & Bennett, 2007). Below we summarize the genes that are strong modifiers of plant form and shape. Polar auxin transport Because auxin acts in a concentrationdependent manner and auxin gradients serve as positional signals, plants have develope ...
A Genetic Mosaic Analysis With a Repressible Cell
... level of barrier epithelia is a key feature common to all organisms of the animal kingdom. To achieve this function, epithelia often acquire a tubular architecture where functional units occur repetitively, form in many cases an interconnected network, and create a large interface of interaction wit ...
... level of barrier epithelia is a key feature common to all organisms of the animal kingdom. To achieve this function, epithelia often acquire a tubular architecture where functional units occur repetitively, form in many cases an interconnected network, and create a large interface of interaction wit ...
Gene mapping and medical genetics Human chromosome 8
... The association of osteopetrosis and renal tubular using somatic cell hybrids.99 Enzyme activity has acidosis has been recognised as a rare recessive been assayed in a variety of patients with chromodisorder.8385 Cerebral calcifications are a feature of some 8 anomalies. These dosage studies showed ...
... The association of osteopetrosis and renal tubular using somatic cell hybrids.99 Enzyme activity has acidosis has been recognised as a rare recessive been assayed in a variety of patients with chromodisorder.8385 Cerebral calcifications are a feature of some 8 anomalies. These dosage studies showed ...
The Terminal Enzymes of Sialic Acid Metabolism: Acylneuraminate
... the enzymes, their thermostability is a special feature that has even been used for enrichment by heat precipitation of the majority of contaminating proteins. G. Taylor (University of Bath), with whom we had a fruitful discussion about this topic, stressed that a thermostable character has often be ...
... the enzymes, their thermostability is a special feature that has even been used for enrichment by heat precipitation of the majority of contaminating proteins. G. Taylor (University of Bath), with whom we had a fruitful discussion about this topic, stressed that a thermostable character has often be ...
Slayer of Lactobacillus helveticus ATCC 12046
... disruption of whole cells using a French press as described by Lortal et a/. (1991). Electron microscopy and labelling withplycationized ferritin. Negative staining was obtained by treating the grids for 2 min with a drop of uranyl acetate (2%, w/v, in distilled water). Thin sectioning was performed ...
... disruption of whole cells using a French press as described by Lortal et a/. (1991). Electron microscopy and labelling withplycationized ferritin. Negative staining was obtained by treating the grids for 2 min with a drop of uranyl acetate (2%, w/v, in distilled water). Thin sectioning was performed ...
MEMCover: integrated analysis of mutual exclusivity and functional
... power to identify ME patterns existing in multiple cancer types can be increased, allowing for detecting across-cancer mutual exclusivity that might not be detected when each tissue type is considered individually. Finally, we assign a pair to the BETWEEN_ME class if the pair pass TO_test but none o ...
... power to identify ME patterns existing in multiple cancer types can be increased, allowing for detecting across-cancer mutual exclusivity that might not be detected when each tissue type is considered individually. Finally, we assign a pair to the BETWEEN_ME class if the pair pass TO_test but none o ...
Determining whether Huntaway dogs treated with AAV2/8 viral
... range of cells, including both dividing and non-dividing cells. Different wild type AAV serotypes demonstrate affinity for different cell types and tissues in vivo and in vitro. For example, AAV1 and AAV7 infect skeletal muscle cells, while AAV2, AAV4, and AAV5 target cells in the central nervous sy ...
... range of cells, including both dividing and non-dividing cells. Different wild type AAV serotypes demonstrate affinity for different cell types and tissues in vivo and in vitro. For example, AAV1 and AAV7 infect skeletal muscle cells, while AAV2, AAV4, and AAV5 target cells in the central nervous sy ...
4 Steroid Hormones
... of homology within their DBDs and LBDs, 97 and 60%, respectively, which results in both receptors binding to the same EREs and exhibiting a similar binding affinity for most endogenous and exogenous ER ligands. The modular nature of the different functional domains and the interdependency of these d ...
... of homology within their DBDs and LBDs, 97 and 60%, respectively, which results in both receptors binding to the same EREs and exhibiting a similar binding affinity for most endogenous and exogenous ER ligands. The modular nature of the different functional domains and the interdependency of these d ...
Progress in the Understanding of the Genetic Etiology of Vertebral
... Golgi apparatus in contrast to other DSL ligands which are expressed on the cell surface.30 Phenotypic Analysis of DLL3 -Null Mice Defines the Developmental Origin of SCD1 Three DLL3 mutant alleles have been described: DLL3pu , DLL3neo , and DLL3oma . The DLL3pu allele was originally described by Gr ...
... Golgi apparatus in contrast to other DSL ligands which are expressed on the cell surface.30 Phenotypic Analysis of DLL3 -Null Mice Defines the Developmental Origin of SCD1 Three DLL3 mutant alleles have been described: DLL3pu , DLL3neo , and DLL3oma . The DLL3pu allele was originally described by Gr ...
Regulation of fatty acid transport and storage: influence of acylation
... influence lipoprotein metabolism. The LPL variant S447X, present in 1822% of individuals, results in alteration of the penultimate amino acid from serine to a stop codon. This mutation is associated with increased LPL mass, but there are conflicting data and interpretations. Evaluation of postprand ...
... influence lipoprotein metabolism. The LPL variant S447X, present in 1822% of individuals, results in alteration of the penultimate amino acid from serine to a stop codon. This mutation is associated with increased LPL mass, but there are conflicting data and interpretations. Evaluation of postprand ...
Differential chromatin packaging of genomic
... and one is the CpG methylation. Almost all imprinted genes have sequence elements that are methylated on only one of the two parental alleles. The differential methylation is a signal that leads to an inactive state of chromatin probably through binding to methyl-CpG-binding proteins, such as MeCP2, ...
... and one is the CpG methylation. Almost all imprinted genes have sequence elements that are methylated on only one of the two parental alleles. The differential methylation is a signal that leads to an inactive state of chromatin probably through binding to methyl-CpG-binding proteins, such as MeCP2, ...
Jürgen Sühnel 3D Structures of Biological Macromolecules
... distortions, loops and side chains, as well as detecting errors in a model. Despite these problems, it is currently possible to model with useful accuracy significant parts of approximately one third of all known protein sequences. ...
... distortions, loops and side chains, as well as detecting errors in a model. Despite these problems, it is currently possible to model with useful accuracy significant parts of approximately one third of all known protein sequences. ...
The families of pathogenesis-related proteins, their activities, and
... LTP4 (cw21) is induced at the mRNA level to the same extent as barley PR-1 upon fungal infection [25]. Although protein levels were not quantified under these conditions, the situation appears sufficiently similar to that of other PR-proteins to include LTPs as PR-14, with the tentative designation ...
... LTP4 (cw21) is induced at the mRNA level to the same extent as barley PR-1 upon fungal infection [25]. Although protein levels were not quantified under these conditions, the situation appears sufficiently similar to that of other PR-proteins to include LTPs as PR-14, with the tentative designation ...
Regulation of transcript encoding the 43K
... purified phage from 24 plaques and analysed DNA from these phage by Southern blots. Phage DNA was digested separately with EcoRl and Stul and Southern blots were probed with 32P-T43k.l cDNA. Based upon the restriction maps of cDNA clones that encode an incorrect C-terminal region (T43k.l) and a seco ...
... purified phage from 24 plaques and analysed DNA from these phage by Southern blots. Phage DNA was digested separately with EcoRl and Stul and Southern blots were probed with 32P-T43k.l cDNA. Based upon the restriction maps of cDNA clones that encode an incorrect C-terminal region (T43k.l) and a seco ...
Nucleosomal structure of sea urchin and starfish sperm chromatin
... sperm cells have been chosen for such analysis since all the histones they contain, for exeption of histone H2B, seemed to be very similar as judged from their amino acid compositions and electrophoretic behavior in two systems. To verify the above we considered also the data available on the primar ...
... sperm cells have been chosen for such analysis since all the histones they contain, for exeption of histone H2B, seemed to be very similar as judged from their amino acid compositions and electrophoretic behavior in two systems. To verify the above we considered also the data available on the primar ...
Accepted Version - CSIRO Research Publications Repository
... (Figure 1). However, in a self-pollinated ddm1 mutant, the BNS gene is methylated and stochastically silenced (Figure 1), indicating that bns is a loss of function epigenetic mutant. The BNS gene is flanked by a LINE (Long interspersed repeated element) sequence in a tail-to-tail orientation, and in ...
... (Figure 1). However, in a self-pollinated ddm1 mutant, the BNS gene is methylated and stochastically silenced (Figure 1), indicating that bns is a loss of function epigenetic mutant. The BNS gene is flanked by a LINE (Long interspersed repeated element) sequence in a tail-to-tail orientation, and in ...
Analysis and nucleotide sequence of an origin of DNA replication in
... stable maintenance in A. calcoaceticus. No rearrangements of the DNA or loss of plasmids are found in that organism, even in the absence of selective pressure, when this sequence is present. A further insertionai inactivation analysis creating lacZ transcriptional fusions suggests that the origin of ...
... stable maintenance in A. calcoaceticus. No rearrangements of the DNA or loss of plasmids are found in that organism, even in the absence of selective pressure, when this sequence is present. A further insertionai inactivation analysis creating lacZ transcriptional fusions suggests that the origin of ...
Phylogenetic and evolutionary analyses of St. Louis encephalitis
... with I (proportion of invariable sites) and C4 (gamma-distributed rates in four categories) (Lanave et al., 1984; Rodriguez et al., 1990; Yang, 1994). Bayesian inference of phylogeny was performed in MrBayes v3.1.2 (Altekar et al., 2004; Ronquist and Huelsenbeck, 2003). The analysis was run twice wi ...
... with I (proportion of invariable sites) and C4 (gamma-distributed rates in four categories) (Lanave et al., 1984; Rodriguez et al., 1990; Yang, 1994). Bayesian inference of phylogeny was performed in MrBayes v3.1.2 (Altekar et al., 2004; Ronquist and Huelsenbeck, 2003). The analysis was run twice wi ...
Structure and functions of lampbrush chromosomes
... with one transcriptional unit and those with two or more. Over the length of 1 μm, one transcriptional unit is transcribed by a densely compacted package of around 13-20 polymerase molecules (Leòn and Kezer, 1990; Macgregor and Varley, 1988; Morgan, 2002). Regulation of LBC transcription is performe ...
... with one transcriptional unit and those with two or more. Over the length of 1 μm, one transcriptional unit is transcribed by a densely compacted package of around 13-20 polymerase molecules (Leòn and Kezer, 1990; Macgregor and Varley, 1988; Morgan, 2002). Regulation of LBC transcription is performe ...
PPT
... distortions, loops and side chains, as well as detecting errors in a model. Despite these problems, it is currently possible to model with useful accuracy significant parts of approximately one third of all known protein sequences. ...
... distortions, loops and side chains, as well as detecting errors in a model. Despite these problems, it is currently possible to model with useful accuracy significant parts of approximately one third of all known protein sequences. ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.