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BROWSING GENES AND GENOMES WITH ENSEMBL
BROWSING GENES AND GENOMES WITH ENSEMBL

splicing
splicing

... • MicroRNAs do not serve solely as modulators of cellular gene activity • Evidence suggests that they also act as antiviral agents by targeting viral mRNAs • David and colleagues demonstrated in 2008 that interferon- stimulates the production of many miRNAs and that several were complementary to pa ...
Basis of preclinical studies_Biochemistry_Practicals_LI
Basis of preclinical studies_Biochemistry_Practicals_LI

... 4. Be able to discuss the significance of alterations of protein amount in blood serum. 1) Biuret reaction Principle: The biuret reaction is a method that can be used to determine the amount of soluble protein in a solution. The biuret reagent (copper sulfate in a strong base) reacts with peptide bo ...
311-320 - CiteSeerX
311-320 - CiteSeerX

... further even at other urea concentrations, the values were lower in the case of the rapeseed protein. In GndHCl solution the mustard 12 S protein reached a value of 16 cc/g at a concentration of 6 Μ (figure 3) and no plateau value was reached. However, the rapeseed 12 S protein attained a constant v ...
Turning floral organs into leaves, leaves into floral organs Koji Goto
Turning floral organs into leaves, leaves into floral organs Koji Goto

... was identified as another MADS-box gene, AGL9 (agamous-like 9) [42••,46]. Other kinds of proteins were not isolated in the yeast two-hybrid screening, suggesting that the entire complex may be composed solely of MADS-box proteins, and that AGL9 may supply a transcriptional activator domain. Notably, ...
Photosynthesis genes in marine viruses yield proteins during host
Photosynthesis genes in marine viruses yield proteins during host

... photosystem II core reaction centre protein D1, and high-lightinducible (hli) genes. Here we show that phage psbA and hli genes are expressed during infection of Prochlorococcus and are cotranscribed with essential phage capsid genes, and that the amount of phage D1 protein increases steadily over t ...
The Arabidopsis NAC Transcription Factor VNI2
The Arabidopsis NAC Transcription Factor VNI2

... that VNI2, which is highly expressed in senescing plant tissues, is also induced by environmental stress conditions, suggesting that it may be involved in modulation of senescence in response to environmental stresses. We therefore decided to examine the potential role of VNI2 in the functional rela ...
Molecular studies of major depressive disorder
Molecular studies of major depressive disorder

... environment can have profound effects on the epigenetic profile of the genome, and that epigenetic marks can directly link environmental factors to gene function. Skewed X-chromosome inactivation is one X-linked epigenetic process that could potentially cause the excess rates of MDD in females, and ...
AllBio_DJK
AllBio_DJK

... A_87_P014348 ...
Anaphase I
Anaphase I

... by mitosis to develop into a multicellular organism • In some plants and most fungi, haploid cells (called spores) are capable of giving rise to multicelluar organisms with only one set of chromosomes - in these organisms, gametes are not produced via meiosis, but by mitosis since there is no need t ...
Plasmodium malariae and P. ovale genomes provide insights into
Plasmodium malariae and P. ovale genomes provide insights into

... species suggests that RBP3 may be essential for invasion of normocytes (Extended Data Fig. 4c). In contrast to other studies1,7,11, we place the rodent malaria parasites as an outgroup to P. ovale but rooted by P. malariae. The rodent malaria parasites could therefore more closely model the biology ...
Developmental and genetic disorders in
Developmental and genetic disorders in

... Robertsonian translocation refers to a special condition where fusion occurs between two acrocentric chromosomes with the loss of genetic information from the short arms of participating chromosomes (Mak and Jarvi, 1996). Base pair mutations can occur in all genes. Substitution or deletion of a sing ...
3 -2 -1 -2 -1 1 2 K
3 -2 -1 -2 -1 1 2 K

... • There are two kinds of scores: raw scores (calculated from a substitution matrix) and bit scores (normalized scores) • Bit scores are comparable between different searches because they are normalized to account for the use of different scoring matrices and different database sizes ...
Microbial Genetics - University of Montana
Microbial Genetics - University of Montana

... 168,895 bp in length The T-odd phages fall into three serological groups: T3 and T7 are related to each other but not to T1 or to T5, which are unrelated. The T7 genome was sequenced in 1983; it is 39,937 bp in length ...
Molecular evolution of swine vesicular disease virus
Molecular evolution of swine vesicular disease virus

... carried out on virus isolates from Asia, where SVDV strains have been isolated almost continually since 1970, and from countries in Europe, where no long-term continuous series of stored isolates was available because either the virus was eliminated or virus isolates were not retained. Phylogenetic ...
Genetic and experimental studies on a pigment
Genetic and experimental studies on a pigment

Phenotypic Stability of trp Operon Recombinant
Phenotypic Stability of trp Operon Recombinant

... The phenotypic stability of RSF2 124-trp was tested in E. coli W3 110 trpAE2 (subsequently designated AEl) under various culture conditions, and in the presence or absence of trpR and tnaA mutations. The results are shown in Table 2. Only MM plus Ap was used in the preculture of strains W3 1 10 trpA ...
Gene–Nutrition Interaction in Human Performance and Exercise
Gene–Nutrition Interaction in Human Performance and Exercise

... remained highly concordant throughout a lifetime, physical activity level did not, suggesting that environmental factors rather than genetic factors are more important in determining an individual’s propensity to be active in later life. Recently, Maia et al.4 studied 411 Portuguese twins of differe ...
Trypsinogen from bovine pancreas Product Number T1143 Storage
Trypsinogen from bovine pancreas Product Number T1143 Storage

... Trypsinogen is a proenzyme (zymogen) form of trypsin which is synthesized in the pancreas. Bovine trypsinogen consists of a single polypeptide chain of 229 amino acids and is cross linked by six disulfide bridges. The proenzyme is activated only after it reaches the lumen of the small intestine. Ent ...
the x chromosome in population genetics
the x chromosome in population genetics

... the X chromosome flow from the characteristics described above. The female-dominated history of the X chromosome makes it an ideal system for studying population-genetic differences between males and females, particularly the differences in mutation rate and in patterns of recombination. The presenc ...
Tumor metastasis-associated human MTA1 gene and its MTA1
Tumor metastasis-associated human MTA1 gene and its MTA1

... Using differential cDNA library screening techniques based on metastatic and nonmetastatic rat mammary adenocarcinoma cell lines, we previously cloned and sequenced the metastasis-associated gene mta1. Using homology to the rat mta1 gene, we cloned the human MTA1 gene and found it to be over-express ...
Sex-chromosome evolution: recent progress and the
Sex-chromosome evolution: recent progress and the

... variety of sex-chromosome systems and the rapid transitions that occur during sex-chromosome evolution in many evolutionary lineages. Sex determination. The two principal ways in which sex chromosomes can be involved in sex determination are by the sex-limited chromosome taking a dominant role (for ...
Reciprocal products of chromosomal translocations in human
Reciprocal products of chromosomal translocations in human

... frequently reported in non-Hodgkin’s lymphoma. BCL-6 is normally expressed in B and CD4+ T cells in germinal centers (GC), and plays an essential role in GC formation [7]. BCL-6 expression is deregulated in non-Hodgkin lymphomas arising from GC B cells, as a result of two distinct mechanisms: (1) ch ...
IndelFR: a database of indels in protein structures and their flanking
IndelFR: a database of indels in protein structures and their flanking

... D512–D518 Nucleic Acids Research, 2012, Vol. 40, Database issue ...
Abnormal anaphase resolution - Journal of Cell Science
Abnormal anaphase resolution - Journal of Cell Science

... (Lehner and O’Farrell, 1989) and string (Edgar and O’Farrell, 1989; Jimenez et al., 1990), is required to regulate the length of G2 phase within these newly cellularized embryonic cells (Edgar and O’Farrell, 1990), whereas zygotic expression of cyclin A is needed for subsequent cell division (Lehner ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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