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ANTIBODY IMMUNE RESPONSE
ANTIBODY IMMUNE RESPONSE

... viral particles. CD8+ T cells are activated by the recognition of viral antigens and induce apoptotic cascade in infected cells leading to their destruction and to the elimination of viral infection. Apoptotic cascade can be induced by molecular pathways such as Fas-FasL, perforine-granzyme, lymphot ...


... of curative intent radiotherapy. It was shown that patients with HNSCC that have a severe deficiency of iNKT cells have a strikingly poor clinical outcome. We studied the effects of iNKT cell activation on Vγ9Vδ2-T cells in Chapter 5, and found that co-activation of iNKT cells enhanced the IFN-γ pro ...
Body Defence
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... B. The bone marrow produces stem cells from which ALL lymphocytes are derived. C. The response to viral infections often involves T killer cells. D. Macrophages and neutrophils have phagocytic and antigen processing and presentation activities. 2. Which statement is FALSE? A. B-cells differentiate i ...
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... Clonal Selection: B cells (and T cells) that encounter stimulating antigen will proliferate into a large group of cells. ƒ Why don’t we produce antibodies against our own antigens? We have developed tolerance to them. ƒ Clonal Deletion: B and T cells that react against self antigens appear to be des ...
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... because combinations are random sometimes receptors will be made that are specific for epitopes on own cells/molecules  as lymphocytes mature in bone marrow or thymus their agn receptors are tested for self reactivity  when discovered are destroyed by apoptosis or rendered nonfunctional ...
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T cell



T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.
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