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Boundless Study Slides
Boundless Study Slides

... connects atrial and ventricular chambers • bundle of His specialized heart muscle cells that transmit electrical impulses from the AV node in the heart to the muscle cells of the heart wall, which contract in response producing the heart beat • diastole relaxation and dilation of the heart chambers, ...
Dilated Cardiomyopathy: a daunting disease of the heart
Dilated Cardiomyopathy: a daunting disease of the heart

... (auscultation) will reveal soft to moderate heart murmurs. The heart rate usually is rapid, often more than 200 beats per minute, in dogs with heart failure. In dogs with PVCs, the erratic heartbeat sometimes can be detected with auscultation in conjunction with feeling the pulse. Normally, for ever ...
Plasma Urocortin 1 in Human Heart Failure
Plasma Urocortin 1 in Human Heart Failure

... factors elevated in heart failure and acute coronary syndromes. Urocortin expression is increased in hypertrophied rat hearts and in the cardiac ventricles of patients with both dilated and hypertrophic cardiomyopathy.18,22 Circulating levels in humans have been reported at ⬇8 pmol/L.23 In human hea ...
Understanding your child`s heart Pulmonary atresia with a
Understanding your child`s heart Pulmonary atresia with a

... friends’ activities, including some sport at school, and for them to judge for themselves what they are able to do. Pulmonary atresia with a VSD is a complex condition. Although surgery can give a reasonable quality of life, it is not possible to correct the heart abnormality and we do not know how ...
an account of a seven year experience with
an account of a seven year experience with

... Its efficacy is excellent in supraventricular arrhythmias, including atrial fibrillation, the most common chronic arrhythmia (12-17). Amiodarone prevents recurrences of atrial fibrillation even better than class I antiarrhythmics, which produced higher mortality than placebo in CAST trial. Other ant ...
Biventricular Pacemakers in Patients With Heart Failure
Biventricular Pacemakers in Patients With Heart Failure

... is used to determine the functional effectiveness of biventricular pacemakers. Surface or transthoracic echocardiography is generally used to determine cardiac output and ejection fraction. Echocardiography is used to show optimization of left ventricular diastolic filling and ejection. It also indi ...
Accuracy of manual QRS duration assessment
Accuracy of manual QRS duration assessment

... These data demonstrate important differences in the concordance rates between manual and computer-calculated QRSd, depending on whether QRSd was defined according to the mean or maximal computer-calculated value. Manual assessment showed good concordance with computer-calculated measurements (.90%) ...
looking eastwards in cardiac genetics finding heart disease
looking eastwards in cardiac genetics finding heart disease

... of athlete heart will usually regress, though whether longstanding changes of older athletes (LV/RV sizes and mass) will regress as effectively in younger ones is not entirely certain. ...
Heart Failure in Sub-Saharan Africa
Heart Failure in Sub-Saharan Africa

... etiologies was similar for both genders. Ischemic heart disease accounted for only 2% of cases, a proportion that is similar to other parts of Africa (15). In a study of 167 consecutive patients admitted to the Yaoundé General Hospital in Cameroon and evaluated by echocardiography, heart failure acc ...
Atrial fibrillation - Giornale Italiano di Cardiologia
Atrial fibrillation - Giornale Italiano di Cardiologia

... Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans, increasing with each decade of life to a prevalence of 5.9% in the population over 65 years of age. It results in an increased mortality and significant morbidity related to thromboembolic stroke, loss of ...
Normal electrocardiographic findings: recognising physiological
Normal electrocardiographic findings: recognising physiological

... abrupt sustained rate increases and decreases and an inappropriate rate response to exercise (both a slowed acceleration and an inappropriately rapid deceleration), as well as any association with clinical symptoms such as exercise intolerance, presyncope and syncope. While the heart rhythm is quite ...
Clustering Heart Rate Dynamics Is Associated with b
Clustering Heart Rate Dynamics Is Associated with b

... associations have largely been characterized by a top-down approach involving a direct comparison of continuous HRV variables among pre-defined groups of subjects (i.e., healthy vs. ill ...
Chapter 28: Pacemakers and Implantable
Chapter 28: Pacemakers and Implantable

... Chapter 28: Pacemakers and Implantable Defibrillators Worksheet Electrophysiology 23. Once a permanent pulse generator is implanted, the only way to alter its pacing parameters is with a _______________________ that communicates with the pacemaker through a wand placed over the pulse generator. 24. ...
Hypertrophic cardiomyopathy: A clinical and genetic update
Hypertrophic cardiomyopathy: A clinical and genetic update

... underlying myocardial ischemia caused by a supply/demand mismatch. This provides a noninvasive measure of the heart’s degree of functionality under conditions of exertion.2,10 Exercise-induced ECG changes can be recorded at rest with exercise and recovery and can be due to subtle ischemic changes se ...
A healthy heart is not a metronome
A healthy heart is not a metronome

... vagal innervation of the ventricles, vagal activity minimally affects ventricular contractility. The response time of the sinus node is very short and the effect of a single efferent vagal impulse depends on the phase of the cardiac cycle at which it is received. Thus, vagal stimulation results in a ...
Cardiovascular Physiology
Cardiovascular Physiology

... • Sets the pace of the heartbeat at 70 bpm • AV node (50 bpm) and Purkinje fibers (25-40 bpm) can act as pacemakers under some conditions ...
insight review articles
insight review articles

... rapidly discharging, spontaneously active, atrial ectopic foci (Fig. 3a), by a single re-entry circuit (Fig. 3b), or by multiple functional reentrant circuits (Fig. 3c). For multiple-circuit re-entry excitation (Fig. 3c), irregular atrial activity is a consequence of the primary arrhythmia mechanism ...
Ca2+ Homeostasis in Normal and Diseased Heart Editorial
Ca2+ Homeostasis in Normal and Diseased Heart Editorial

... serves as a second messenger in signaling pathways, the tuning of Ca2+ release is precisely regulated by varieties of proteins, kinases, and ions. In fact, any mutation in LTCC, RyR, or other Ca2+ related protein may lead to ventricular arrhythmia, impaired contractility, or cardiomyopathy. Catechol ...
Electrocardiography changes in bipolar patients during - EU-GEI
Electrocardiography changes in bipolar patients during - EU-GEI

... channels in sinus nodal pacemaker activity, lithium may cause a sinus node dysfunction through the failure of impulse generation or conduction into the adjacent atrial myocardium [24,26]. The decrease in adrenergic response and the complex interaction between sodium and pacemaker (L-type calcium and ...
Frog Heart Experiment
Frog Heart Experiment

... dissection pan with the blade oriented perpendicular to the thread. The thread from the frog heart to the transducer should be quit flat (horizontal) so that you apply tension to the long axis of the heart. See Figure 6 for reference. (d) Use alligator clips to attach a wire between the metal dissec ...
Molecular and Structural Basis for Cardiac Arrhythmias
Molecular and Structural Basis for Cardiac Arrhythmias

... high degree of current-to-load (source – sink) mismatch. It is still not clear how a small amount of depolarizing current (source) provided by the limited number of cells in the sinus node or a thin bundle of Purkinje fibers can activate the much larger mass of atrial or ventricular muscle to which ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... described channels and channel-related proteins (A kinase anchoring protein, AKAP) can induce arrhythmias. Electrophysiological mechanisms of arrhythmia result from conduction disturbances and/or the formation of beats. Conduction abnormalities occur in the type of reentry in which unidirectional co ...
Normal electrocardiographic findings: recognising
Normal electrocardiographic findings: recognising

... abrupt sustained rate increases and decreases and an inappropriate rate response to exercise (both a slowed acceleration and an inappropriately rapid deceleration), as well as any association with clinical symptoms such as exercise intolerance, presyncope and syncope. While the heart rhythm is quite ...
Cardioversion of "Common" Atrial
Cardioversion of "Common" Atrial

... ered during and following cardioversion. Although the for which anticoagulation is continued follow¬ period ing cardioversion is debatable, it could be guided by the duration of atrial systole. All three patients who had embolic events had ev¬ idence of heart disease: cardiomyopathy in the first pat ...
Heart Surface Motion Estimation Framework for Robotic
Heart Surface Motion Estimation Framework for Robotic

... In this section, the behavior of the heart surface as a distributed phenomenon is formulated by means of a PDE. For this purpose, after a brief analysis of the heart geometry, the possible assumptions are justified and the thin plate model of the heart surface is proposed. The purpose of the heart s ...
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Heart arrhythmia

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