Creating 3-Dimensional Graph Structures with DNA
... through the graph can be produced by using both types of edge blocks, circular molecules that pass through a vertex up to three times (Fig. 8) also are possible. Each of the inner three double strands presented in Fig. 3 can be a part of the same circular double stranded molecule. We therefore need ...
... through the graph can be produced by using both types of edge blocks, circular molecules that pass through a vertex up to three times (Fig. 8) also are possible. Each of the inner three double strands presented in Fig. 3 can be a part of the same circular double stranded molecule. We therefore need ...
CpG Mutation Rates in the Human Genome Are
... requires the attack of H3O1 on the N-3 position, followed by the addition of H2O to the C-4 position, neither of which are accessible to water in double-stranded DNA (Frederico, Kunkel, and Shaw 1993). The measured activation energies of this reaction are identical in single-stranded and doublestran ...
... requires the attack of H3O1 on the N-3 position, followed by the addition of H2O to the C-4 position, neither of which are accessible to water in double-stranded DNA (Frederico, Kunkel, and Shaw 1993). The measured activation energies of this reaction are identical in single-stranded and doublestran ...
08.seg_dup_els - NYU Computer Science
... whole-genome duplications. For instance, from the sequence of a related species, Kluyveromyces waltii, that diverged from Saccharomyces cerevisiae before the duplication event and from the comparative study on the gene orders and copy numbers, scientists gathered the most convincing evidence for a w ...
... whole-genome duplications. For instance, from the sequence of a related species, Kluyveromyces waltii, that diverged from Saccharomyces cerevisiae before the duplication event and from the comparative study on the gene orders and copy numbers, scientists gathered the most convincing evidence for a w ...
Genetic Technology - McGraw Hill Higher Education
... of copies of a DNA sequence of interest. The technique also takes advantage of advanced lab equipment that can artificially manufacture short pieces of DNA of any sequence it is programmed to produce. The DNA synthesizer cannot easily make entire genes, but it can make small fragments that can act a ...
... of copies of a DNA sequence of interest. The technique also takes advantage of advanced lab equipment that can artificially manufacture short pieces of DNA of any sequence it is programmed to produce. The DNA synthesizer cannot easily make entire genes, but it can make small fragments that can act a ...
Paper - Revision Science
... (iii) Multiple sclerosis is a progressive, degenerative disease of the nervous system in which the material referred to in (b)(i) is destroyed. Symptoms include increasing muscle weakness and loss of vision. Suggest an explanation for these symptoms. ...
... (iii) Multiple sclerosis is a progressive, degenerative disease of the nervous system in which the material referred to in (b)(i) is destroyed. Symptoms include increasing muscle weakness and loss of vision. Suggest an explanation for these symptoms. ...
introduction
... 1992). Additionally, the 6kb linear genome encoded bacterial-type rRNAs which were different from those encoded by the 35kb circle (Feagin et aI., 1997). Sequence analysis revealed that the 35kb element was similar to chloroplast genomes, containing an inverted repeat of ribosomal RNA genes ...
... 1992). Additionally, the 6kb linear genome encoded bacterial-type rRNAs which were different from those encoded by the 35kb circle (Feagin et aI., 1997). Sequence analysis revealed that the 35kb element was similar to chloroplast genomes, containing an inverted repeat of ribosomal RNA genes ...
CfE Higher Biology Unit 1: DNA and the Genome
... educational purposes within their establishment providing that no profit accrues at any stage, Any other use of the materials is governed by the general copyright statement that follows. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted i ...
... educational purposes within their establishment providing that no profit accrues at any stage, Any other use of the materials is governed by the general copyright statement that follows. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted i ...
Slides
... §Uses sequence to synthesize a single-stranded DNA to extend the 3′ strand §Telomere end-binding proteins (TEBPs) –binds to GT rich telomere sequences §Telomere repeat-binding factors (TRFs)– secure 3’ end ...
... §Uses sequence to synthesize a single-stranded DNA to extend the 3′ strand §Telomere end-binding proteins (TEBPs) –binds to GT rich telomere sequences §Telomere repeat-binding factors (TRFs)– secure 3’ end ...
64$ CfE Higher Biology Unit 1: DNA and the
... • All cells store their genetic information in the base sequence of DNA. • The structure of a DNA nucleotide is composed of deoxyribose sugar, a phosphate and a base. • Nucleotides bond to form a sugar-phosphate backbone. • Base pairs (adenine, thymine, guanine and cytosine) hold the two strands tog ...
... • All cells store their genetic information in the base sequence of DNA. • The structure of a DNA nucleotide is composed of deoxyribose sugar, a phosphate and a base. • Nucleotides bond to form a sugar-phosphate backbone. • Base pairs (adenine, thymine, guanine and cytosine) hold the two strands tog ...
64$ CfE Higher Biology Unit 1: DNA and the
... • All cells store their genetic information in the base sequence of DNA. • The structure of a DNA nucleotide is composed of deoxyribose sugar, a phosphate and a base. • Nucleotides bond to form a sugar-phosphate backbone. • Base pairs (adenine, thymine, guanine and cytosine) hold the two strands tog ...
... • All cells store their genetic information in the base sequence of DNA. • The structure of a DNA nucleotide is composed of deoxyribose sugar, a phosphate and a base. • Nucleotides bond to form a sugar-phosphate backbone. • Base pairs (adenine, thymine, guanine and cytosine) hold the two strands tog ...
UV-Targeted Dinucleotides Are Not Depleted in Light
... and producing genome-wide biases (Chen et al. 2004). The rather universal overrepresentation of TpT dinucleotides in all genomes is surprising, even though it was not always statistically significant. Unlike eukaryotic mRNA, where poly-A stretches have a known essential function, there is no evidenc ...
... and producing genome-wide biases (Chen et al. 2004). The rather universal overrepresentation of TpT dinucleotides in all genomes is surprising, even though it was not always statistically significant. Unlike eukaryotic mRNA, where poly-A stretches have a known essential function, there is no evidenc ...
physical maps
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
Site-Specific Integration of Transgenes in
... A1 was positive for both the 5# end and 3# end assays specific to RMCE (Fig. 2, A and B), negative for either the 5# end or the 3# end assays specific to the target (Fig. 2, C and D), and positive for a small excisionspecific band amplified by the full-length PCR (Fig. 2E). Since one copy of RMCE wa ...
... A1 was positive for both the 5# end and 3# end assays specific to RMCE (Fig. 2, A and B), negative for either the 5# end or the 3# end assays specific to the target (Fig. 2, C and D), and positive for a small excisionspecific band amplified by the full-length PCR (Fig. 2E). Since one copy of RMCE wa ...
The Differential Killing of Genes by Inversions in Prokaryotic Genomes
... strand is located on the leading strand, it is assumed that “the gene lies on the leading strand.” In prokaryotic genomes, the leading and lagging roles of DNA strands are predetermined by location of the origin of replication and the terminus of replication. Thus, a gene stays at the same position ...
... strand is located on the leading strand, it is assumed that “the gene lies on the leading strand.” In prokaryotic genomes, the leading and lagging roles of DNA strands are predetermined by location of the origin of replication and the terminus of replication. Thus, a gene stays at the same position ...
DNA-dependent protein kinase in nonhomologous end joining: a
... clear that the DNA-PKCS cap has to be removed or altered before religation of the DNA ends and repair of the DSB can take place. Several authors have demonstrated that autophosphorylation of DNA-PKCS results in release of the cap and accessibility of the DNA termini for either processing enzymes or ...
... clear that the DNA-PKCS cap has to be removed or altered before religation of the DNA ends and repair of the DSB can take place. Several authors have demonstrated that autophosphorylation of DNA-PKCS results in release of the cap and accessibility of the DNA termini for either processing enzymes or ...
annotation and analysis of newly discovered mycobacteriophage
... characterize their phage, and then one or more is sequenced by the class. During the course of this project, many mycobacteriophage genomes have been characterized and added to existing databases; this success has driven the production of a mycobacteriophage-specific database that contains all the m ...
... characterize their phage, and then one or more is sequenced by the class. During the course of this project, many mycobacteriophage genomes have been characterized and added to existing databases; this success has driven the production of a mycobacteriophage-specific database that contains all the m ...
LAB 1: Scientific Method/Tools of Scientific Inquiry
... one of four possible nitrogenous bases (“bases” for short) on the other. The phosphate group is acidic and thus negatively charged. This is why DNA has a net negative charge. Because all nucleotides in DNA contain deoxyribose they are called deoxyribonucleotides, though for simplicity we will just c ...
... one of four possible nitrogenous bases (“bases” for short) on the other. The phosphate group is acidic and thus negatively charged. This is why DNA has a net negative charge. Because all nucleotides in DNA contain deoxyribose they are called deoxyribonucleotides, though for simplicity we will just c ...
(2) in ppt - NYU Computer Science
... to break the DNA at specific sites. Since DNA molecules are under slight tension, the cut fragments of DNA relax like entropic springs, leaving small visible gaps corresponding to the positions of the restriction site (Fig 4). 1. A restriction enzyme is a highly specific molecular scissor that recog ...
... to break the DNA at specific sites. Since DNA molecules are under slight tension, the cut fragments of DNA relax like entropic springs, leaving small visible gaps corresponding to the positions of the restriction site (Fig 4). 1. A restriction enzyme is a highly specific molecular scissor that recog ...
draft - IC
... When more than two genomes are considered, we have the more challenging problem of rearrangement-based phylogeny reconstruction, where we want to nd a tree that minimizes the total number of rearrangement events. Early approaches were based on a breakpoint distance (e.g., BPAnalysis [13], and GRAPP ...
... When more than two genomes are considered, we have the more challenging problem of rearrangement-based phylogeny reconstruction, where we want to nd a tree that minimizes the total number of rearrangement events. Early approaches were based on a breakpoint distance (e.g., BPAnalysis [13], and GRAPP ...
achondroplasia
... chance that the child will inherit one abnormal gene from each parent and have severe skeletal abnormalities that lead to early death. A child who does not inherit the gene will be completely free of the condition, and cannot pass it on to his or her own children. ...
... chance that the child will inherit one abnormal gene from each parent and have severe skeletal abnormalities that lead to early death. A child who does not inherit the gene will be completely free of the condition, and cannot pass it on to his or her own children. ...
Probable presence of an ubiquitous cryptic mitochondrial gene on
... Background: Mitochondria mediate most of the energy production that occurs in the majority of eukaryotic organisms. These subcellular organelles contain a genome that differs from the nuclear genome and is referred to as mitochondrial DNA (mtDNA). Despite a disparity in gene content, all mtDNAs enco ...
... Background: Mitochondria mediate most of the energy production that occurs in the majority of eukaryotic organisms. These subcellular organelles contain a genome that differs from the nuclear genome and is referred to as mitochondrial DNA (mtDNA). Despite a disparity in gene content, all mtDNAs enco ...
Cinteny is a flexible and efficient tool for analysis of synteny and
... for multiple genomes. In addition to annotated genomes, which are available for interactive browsing and assessment of synteny and evolutionary distances in terms of orthologous genes, Cinteny can be used with user provided discrete objects, such as sequence tags or other evolutionarily conserved ma ...
... for multiple genomes. In addition to annotated genomes, which are available for interactive browsing and assessment of synteny and evolutionary distances in terms of orthologous genes, Cinteny can be used with user provided discrete objects, such as sequence tags or other evolutionarily conserved ma ...
Sequencing Crop Genomes - Tropical Life Sciences Research
... which is crucial for successful breeding programmes. Identification of the key genes underlying a trait enables the transfer of the trait to another cultivar or species by genetic modification; alternatively, these traits may be incorporated into a cultivar by marker-assisted selection (Edwards & Ba ...
... which is crucial for successful breeding programmes. Identification of the key genes underlying a trait enables the transfer of the trait to another cultivar or species by genetic modification; alternatively, these traits may be incorporated into a cultivar by marker-assisted selection (Edwards & Ba ...
OrthoMaM: a database of orthologous genomic markers for
... We focused on orthologous exons rather than on fulllength transcripts in order to provide biologists with single continuous fragments potentially amplifiable from genomic DNA. Working with RNA extraction followed by RT-PCR would require a quality of tissue preservation that is not achieved in the va ...
... We focused on orthologous exons rather than on fulllength transcripts in order to provide biologists with single continuous fragments potentially amplifiable from genomic DNA. Working with RNA extraction followed by RT-PCR would require a quality of tissue preservation that is not achieved in the va ...
Transduction of DNA information through water and electromagnetic
... Instead of magnetizing water in a tube placed inside a solenoid reading the modulated current from the recorded EMS signature, we placed inside the solenoid a flask containing cultured cells; the flask was placed in a vertical position for cells growing in suspension, and in a horizontal position fo ...
... Instead of magnetizing water in a tube placed inside a solenoid reading the modulated current from the recorded EMS signature, we placed inside the solenoid a flask containing cultured cells; the flask was placed in a vertical position for cells growing in suspension, and in a horizontal position fo ...
Mitochondrial DNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants, in the chloroplast.In humans, mitochondrial DNA can be assessed as the smallest chromosome coding for 37 genes and containing approximately 16,600 base pairs. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. In most species, including humans, mtDNA is inherited solely from the mother.The DNA sequence of mtDNA has been determined from a large number of organisms and individuals (including some organisms that are extinct), and the comparison of those DNA sequences represents a mainstay of phylogenetics, in that it allows biologists to elucidate the evolutionary relationships among species. It also permits an examination of the relatedness of populations, and so has become important in anthropology and field biology.