Human RIF1 and protein phosphatase 1 stimulate DNA replication
... regulation. 2. They observe a new role for RIF1 in origin stabilization, which adds another chapter to the ever-growing RIF1 tome. I believe the intellectual merit of this paper is high and it should be accepted for publication, yet there are issues that will make the paper stronger, as outlined bel ...
... regulation. 2. They observe a new role for RIF1 in origin stabilization, which adds another chapter to the ever-growing RIF1 tome. I believe the intellectual merit of this paper is high and it should be accepted for publication, yet there are issues that will make the paper stronger, as outlined bel ...
International Agency for Research on Cancer (IARC)
... experimental animals. Animal species, such as the mouse, that are resistant to aflatoxin carcinogenesis have three to five times more glutathione S-transferase activity than susceptible species, such as the rat. Humans have less glutathione S-transferase activity for 8,9-epoxide conjugation than rat ...
... experimental animals. Animal species, such as the mouse, that are resistant to aflatoxin carcinogenesis have three to five times more glutathione S-transferase activity than susceptible species, such as the rat. Humans have less glutathione S-transferase activity for 8,9-epoxide conjugation than rat ...
Isolation, Characterization, and Annotation: The Search for Novel
... to the host, penetrates the cell membrane and injects its DNA. The genetic information can then follow two potential paths. In the lysogenic cycle, the DNA is incorporated into the host genome as a prophage and remains a part of the host’s genome as long as conditions remain stable for the prophage. ...
... to the host, penetrates the cell membrane and injects its DNA. The genetic information can then follow two potential paths. In the lysogenic cycle, the DNA is incorporated into the host genome as a prophage and remains a part of the host’s genome as long as conditions remain stable for the prophage. ...
Nuclear Factor-κB Modulates the p53 Response in Neurons
... However, it is likely that numerous other signals implicated in neuronal death are regulated by DNA damage also. Because it is the balance of all signals that control death, it has become important to delineate additional death/survival-promoting elements and ascertain how they are linked to the gro ...
... However, it is likely that numerous other signals implicated in neuronal death are regulated by DNA damage also. Because it is the balance of all signals that control death, it has become important to delineate additional death/survival-promoting elements and ascertain how they are linked to the gro ...
Rotaphor System 6.0
... 1.2.1 Rotating Field Electrophoresis (ROFE) In contrast to conventional PFGE instruments with fixed electrodes the patented Rotaphor® system features free rotating electrodes. Thus any angle can be set for the electric field. Changing field angles over the time are achieved by the precise movement o ...
... 1.2.1 Rotating Field Electrophoresis (ROFE) In contrast to conventional PFGE instruments with fixed electrodes the patented Rotaphor® system features free rotating electrodes. Thus any angle can be set for the electric field. Changing field angles over the time are achieved by the precise movement o ...
Mechanisms of Transcription-Replication
... function did not depend on transcription per se (7), but was caused by a polar contrahelicase activity of the DNA-binding protein Fob1 (18). Only when the FOB1 gene was deleted and the number of rRNA gene repeats was reduced was transcription-replication collision at the ribosomal locus actually det ...
... function did not depend on transcription per se (7), but was caused by a polar contrahelicase activity of the DNA-binding protein Fob1 (18). Only when the FOB1 gene was deleted and the number of rRNA gene repeats was reduced was transcription-replication collision at the ribosomal locus actually det ...
Inhibition of RNA Synthesis by Anthracycline Analogs
... these drugs is a cardiopulmonary syndrome (Bonadonna et al., 1969) consisting of tachycardia, with or without arrhythmia, hypotension, gallop rhythm, tachypnea, and congestive heart failure, not relieved by digitalis. ...
... these drugs is a cardiopulmonary syndrome (Bonadonna et al., 1969) consisting of tachycardia, with or without arrhythmia, hypotension, gallop rhythm, tachypnea, and congestive heart failure, not relieved by digitalis. ...
Analysis of Cross Sequence Similarities for Multiple - PolyU
... Abstract: Current DNA compression algorithms rely on finding repetitions within the DNA sequence so that similar subsequences can be encoded by referencing to each other. We explore similarities between different chromosomes of the sequence ‘Saccharomyces cerevisiae’. These similarities are characte ...
... Abstract: Current DNA compression algorithms rely on finding repetitions within the DNA sequence so that similar subsequences can be encoded by referencing to each other. We explore similarities between different chromosomes of the sequence ‘Saccharomyces cerevisiae’. These similarities are characte ...
Evidence that MEK1 positively promotes
... first meiotic non-disjunction. In some organisms the mechanisms ensuring that sufficient DSBs are repaired using crossovers could involve stochastic processes. For example, in Schizosaccharomyces pombe there is evidence that recombination intermediates [joint molecules (JMs)] are more abundant among si ...
... first meiotic non-disjunction. In some organisms the mechanisms ensuring that sufficient DSBs are repaired using crossovers could involve stochastic processes. For example, in Schizosaccharomyces pombe there is evidence that recombination intermediates [joint molecules (JMs)] are more abundant among si ...
as a PDF - CiteSeerX
... replication exhibited both enhanced LIR excision and interchromosomal recombination (28, 29). We have investigated the impact of LIRs and altered replication on both homeologous and homologous intrachromosomal recombination. The altered replication is due to a mutation, pol3-t, in the DNA polymerase ...
... replication exhibited both enhanced LIR excision and interchromosomal recombination (28, 29). We have investigated the impact of LIRs and altered replication on both homeologous and homologous intrachromosomal recombination. The altered replication is due to a mutation, pol3-t, in the DNA polymerase ...
DNA cytosine methylation in plant development
... (Bird, 2002). A striking difference in the cytosine methylation patterns in plants from those in animals is that although methylation is predominantly occurring at the CG dinucleotides in plants, it is not confined to these sites; instead, methylation also occurs at CHG (where H is A, C or T) and as ...
... (Bird, 2002). A striking difference in the cytosine methylation patterns in plants from those in animals is that although methylation is predominantly occurring at the CG dinucleotides in plants, it is not confined to these sites; instead, methylation also occurs at CHG (where H is A, C or T) and as ...
pyrimidine
... Uses short primer that attaches to the 3’ end of the ssDNA, after which a specially engineered DNA polymerase Each vial includes one dideoxyXTP and 3 ordinary dXTPs; the dideoxyXTP will be incorporated but will halt synthesis because the 3’ position is blocked. See figs. 11.3 & 11.4 for how these ar ...
... Uses short primer that attaches to the 3’ end of the ssDNA, after which a specially engineered DNA polymerase Each vial includes one dideoxyXTP and 3 ordinary dXTPs; the dideoxyXTP will be incorporated but will halt synthesis because the 3’ position is blocked. See figs. 11.3 & 11.4 for how these ar ...
A Novel CpG Island Set Identifies Tissue-Specific
... was digested with MseI (TTAA) [20] and fractionated over the CXXC column (Figure 1B). The reasoning behind use of Mse1 [20] was to cut AT-rich bulk genomic DNA into small fragments (predicted average ¼ 123 bp), but to leave CGIs relatively intact (predicted average ¼ 625 bp). As bulk genomic DNA has ...
... was digested with MseI (TTAA) [20] and fractionated over the CXXC column (Figure 1B). The reasoning behind use of Mse1 [20] was to cut AT-rich bulk genomic DNA into small fragments (predicted average ¼ 123 bp), but to leave CGIs relatively intact (predicted average ¼ 625 bp). As bulk genomic DNA has ...
EndoFree® Plasmid Purification Handbook
... contain, their size, and the size of insert. The protocols in this handbook are grouped according to the copy number of the plasmid or cosmid to be purified. For more details, visit our plasmid resource page at www.qiagen.com/goto/plasmidinfo and click on the link “General Considerations for Optimal ...
... contain, their size, and the size of insert. The protocols in this handbook are grouped according to the copy number of the plasmid or cosmid to be purified. For more details, visit our plasmid resource page at www.qiagen.com/goto/plasmidinfo and click on the link “General Considerations for Optimal ...
Bacillus subtilis serine/threonine protein kinase YabT is involved in
... identified a substrate of YabT, which is the general DNArecombinase RecA, involved in homologous recombination and DNA damage repair (Lusetti and Cox, 2002). DNA recombinases participate in homologous recombination and recombinational repair of DNA double-strand breaks in all living forms (Kuzminov, ...
... identified a substrate of YabT, which is the general DNArecombinase RecA, involved in homologous recombination and DNA damage repair (Lusetti and Cox, 2002). DNA recombinases participate in homologous recombination and recombinational repair of DNA double-strand breaks in all living forms (Kuzminov, ...
Molecular Biology and Applied Genetics
... gene/protein does, the resulting conclusions are much stronger than if one only use one of these strategies. ...
... gene/protein does, the resulting conclusions are much stronger than if one only use one of these strategies. ...
ERROR-PRONE REPAIR DNA POLYMERASES IN PROKARYOTES
... We also describe the properties of several repair polymerases that are not Y-family members; two examples are E. coli pol II and eukaryotic pol . Questions abound. Why do EP DNA polymerases even exist? Where are they found? When and how do they function? The potential benefit to the cell of using E ...
... We also describe the properties of several repair polymerases that are not Y-family members; two examples are E. coli pol II and eukaryotic pol . Questions abound. Why do EP DNA polymerases even exist? Where are they found? When and how do they function? The potential benefit to the cell of using E ...
Bacteriophage A cloning system for the construction of
... libraries. The wild-type A genome contains five BamHI, five EcoRI, and seven Hindu restriction sites that have all been removed from the genome of AORF8. Sites for these endonucleases are present within the multiple cloning site of AORF8. We report a method for preparing cDNAs that can be cloned in ...
... libraries. The wild-type A genome contains five BamHI, five EcoRI, and seven Hindu restriction sites that have all been removed from the genome of AORF8. Sites for these endonucleases are present within the multiple cloning site of AORF8. We report a method for preparing cDNAs that can be cloned in ...
