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Can a few non-coding mutations make a human brain?
Can a few non-coding mutations make a human brain?

... elaborate a complex language, we must answer two challenging questions. The first is how to link human cognition to number of neurons, brain size, a highly developed cortex, and particular neuroanatomical differences. The neurobiological bases of our linguistic capacity, for example, are not complet ...
Impact of early-life stress on the medial prefrontal cortex functions
Impact of early-life stress on the medial prefrontal cortex functions

... mPFC dysfunction in animals exposed to ELS, numerous biochemical, morphological and electrophysiological reports have shown that ELS affects neural activity and synaptic plasticity within the mPFC [3, 14–16, 60, 62]. Synaptic plasticity underlies the continuous ability of the brain to adapt to speci ...
File - cbcpsychology
File - cbcpsychology

... Participants are matched according to the variable(s) whose influence should be controlled e.g. intelligence, memory ability, etc. The pairings could also be based on characteristics such as I.Q., age, Controls the effects of the variable(s) on which participants are matched, thus MatchedPairs minim ...
Document
Document

... Optogenetics introduces light responsive proteins into cultured cells or the brains of live animals allowing for investigation of the structure and function of neural networks. By turning genetically specified populations of neurons on or off with light, the combination of genetics and optics can co ...
(fMRI) in Brain Tumour Patients
(fMRI) in Brain Tumour Patients

... of new functional deficits post-operatively. For optimal results, the relationship between the tumour margins and eloquent brain regions needs to be established as accurately as possible. The gold standard for such assessment is intraoperative ECM, which has in fact been shown to significantly modif ...
Tracking Whole-Brain Connectivity Dynamics in the Resting State
Tracking Whole-Brain Connectivity Dynamics in the Resting State

... Considering the strong evidence for fluctuations in FC, how then should we best investigate spontaneous variations in the framework of a large group study? In contrast to investigations with task designs or paced experimental manipulations, the variety of mental states experienced during rest and the ...
Reverse-Engineering the Human Auditory Pathway
Reverse-Engineering the Human Auditory Pathway

... visualizing these processes in isolation at near biological resolution in real-time, and it was possible to raise venture capital funding to begin the project. By 2008, these advances had permitted the development of products in the area of two-microphone noise reduction for mobile phones, leading t ...
Cortical activation and synchronization during sentence
Cortical activation and synchronization during sentence

... measure the synchronization is to compute the correlation (Friston, 1994) or covariance (Horwitz et al., 1998) between the activation levels in two activated areas. In particular, functional connectivity as defined by Friston (1994), and as we will use it, refers to the correlation between the activ ...
The Neuropsychology of Reading Disorders
The Neuropsychology of Reading Disorders

... nerve fibers which connect each hemisphere. d) Nuclei: Consist of bundles of nerve cells with a common function. For instance, the thalamus serves as a relay center in the brain to process all sensory input except for smell. * At birth, human brain weighs 25% of adult weight compared to chimpanzee's ...
- Wiley Online Library
- Wiley Online Library

... insular and cingulate cortices that receive these inputs can be regarded as limbic sensory and limbic motor cortices, respectively, because their major descending projections are to PB and PAG, respectively.5,14,15 The activation in the fundus of the central sulcus (area 3a) could be a viscero-motor ...
Hemispheric Asymmetry Reduction in Older Adults
Hemispheric Asymmetry Reduction in Older Adults

... episodic and working memory processes, but also for simple cognitive processes, such as face matching. In a more recent study by Grady, McIntosh, Horwitz, and Rapoport (2000), age-related asymmetry reductions during face matching were also found. In this study, face matching was investigated for bot ...
document1004
document1004

... action into the conceptual framework. Thus theory of functional systems, firstly, included the isomorphic system-creating factor into the conceptual apparatus of systemic approach, and, secondly, it radically changed the understanding of the causation of behavior. According to the classic interpreta ...
Emotion, Memory and the Brain - sdsu
Emotion, Memory and the Brain - sdsu

... same way that other events do—via transmission to the lateral nucleus. Although our experiments had identified a subcortical sensory pathway that gave rise to fear conditioning, we did not dismiss the importance of the cortex. The interaction of subcortical and cortical mechanisms in emotion remains ...
Nervous_system_Tissue_Overview0
Nervous_system_Tissue_Overview0

...  Cells specialized to transmit messages – can conduct but cannot replicate  Have 3 specialized characteristics  Longevity: with nutrition, can live as long as you do  Amitotic: unable to reproduce themselves (so cannot be replaced) ...
rapid eye movement sleep deprivation induces acetylcholinesterase
rapid eye movement sleep deprivation induces acetylcholinesterase

... ergic cell groups of the ponto mesencephalic tegmentum after paradoxical sleep deprivation and recovery. J Neurosci ...
The central nervous system, or CNS for short, is composed of the
The central nervous system, or CNS for short, is composed of the

... enzyme that breaks proteoglycans. The sugars were taken off of the proteins, creating a less complex structure (Cafferty, et al., 2007). Because the proteoglycans broke into shorter, smaller pieces, neurons were able to grow into more areas. Reductions of proteoglycans also allowed ...
- PhilSci
- PhilSci

... explores this issue, asking: Currently, what do scientists learn from designing, building, and running large-scale neural simulations? One plausible answer is that at least for some such simulations scientists learn about the computational performance of the simulating system. Plausible as it sounds ...
rview
rview

... C) recording what part of the brain a person indicates that she feels is activated during a specific behavioral task D) recording changes in neural activity that occur in specific parts of the brain when a person or animal is engaged in a particular mental or behavioral task 50. Which of these is NO ...
An international registry for neurodegeneration with brain iron
An international registry for neurodegeneration with brain iron

... volumetry by imaging, treatments and trials. The disease course is captured by standardized scales measuring dystonia severity, quality of life and sleep, functional independence, cognition, motor functioning and activity of daily living. The annually entered information enables a longitudinal recon ...
melanin in the body
melanin in the body

... electrical discharge aka 'nerve impulse'. Neurons are found in the brain and spinal cord aka the central nervous system (CNS), and peripheral nerves system (located outside of the CNS and connects the CNS to organs and limbs of the body). Brain neurons that contain melanin are called neuromelanin. N ...
The development of emotion regulation: an fMRI
The development of emotion regulation: an fMRI

... includes the posterior cingulate cortex, superior temporal sulcus and the temporal poles. These regions are thought to support the ability to attribute mental states to the self and others, which underlies many complex social cognitive abilities, such as self-referential judgments, mentalizing, pers ...
The brain-machine disanalogy revisited
The brain-machine disanalogy revisited

... tremendous advances in certain aspects of computer technology and also the more modest advances in understanding of biological information processing. In honor of Michael, I will revisit his thoughts from my own limited perspective, admitting at the outset, that I will not attempt to include Michael ...
Document
Document

... mixed effects in the brain, a not unusual occurrence with psychoactive drugs. Even caffeine, which is generally (55) known only for its stimulatory effects, displays this property, depressing mouse locomotion at very low concentrations and stimulating it at higher ones. 1. The primary purpose of the ...
PDF file
PDF file

M&E and the Frontal Lobes
M&E and the Frontal Lobes

... lesions and among patients with additional impairment of memory ability. Another syndrome that is similar to confabulation is reduplication. Here, the patient with a frontal lobe lesion confabulates that the current environment, usually the hospital, is actually another place that is similar to the ...
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Cognitive neuroscience



Cognitive neuroscience is an academic field concerned with the scientific study of biological substrates underlying cognition, with a specific focus on the neural substrates of mental processes. It addresses the questions of how psychological/cognitive functions are produced by neural circuits in the brain. Cognitive neuroscience is a branch of both psychology and neuroscience, overlapping with disciplines such as physiological psychology, cognitive psychology, and neuropsychology. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neuropsychology, and computational modeling.Due to its multidisciplinary nature, cognitive neuroscientists may have various backgrounds. Other than the associated disciplines just mentioned, cognitive neuroscientists may have backgrounds in neurobiology, bioengineering, psychiatry, neurology, physics, computer science, linguistics, philosophy, and mathematics.Methods employed in cognitive neuroscience include experimental paradigms from psychophysics and cognitive psychology, functional neuroimaging, electrophysiology, cognitive genomics, and behavioral genetics. Studies of patients with cognitive deficits due to brain lesions constitute an important aspect of cognitive neuroscience. Theoretical approaches include computational neuroscience and cognitive psychology.Cognitive neuroscience can look at the effects of damage to the brain and subsequent changes in the thought processes due to changes in neural circuitry resulting from the ensued damage. Also, cognitive abilities based on brain development is studied and examined under the subfield of developmental cognitive neuroscience.
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