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Overview of a typical protein identification by MALDI-TOF
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Ion

An ion (/ˈaɪən, -ɒn/) is an atom or a molecule in which the total number of electrons is not equal to the total number of protons, giving the atom or molecule a net positive or negative electrical charge.Ions can be created, by either chemical or physical means, via ionization. In chemical terms, if a neutral atom loses one or more electrons, it has a net positive charge and is known as a cation. If an atom gains electrons, it has a net negative charge and is known as an anion. An ion consisting of a single atom is an atomic or monatomic ion; if it consists of two or more atoms, it is a molecular or polyatomic ion. Because of their electric charges, cations and anions attract each other and readily form ionic compounds, such as salts. In the case of physical ionization of a medium, such as a gas, what are known as ""ion pairs"" are created by ion impact, and each pair consists of a free electron and a positive ion.
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