Critical Time Window of Neuronal Cholesterol Synthesis during
... such as clasping, tremor, or convulsions. Nevertheless, by quantitative PCR analysis on genomic DNA of 1-year-old SQS/ CaMKII-cre mutants, 39 ⫾ 3% of cortical cells were recombined. This value indicates that the vast majority of projection neurons was targeted (Ren et al., 1992). Neuronal survival, ...
... such as clasping, tremor, or convulsions. Nevertheless, by quantitative PCR analysis on genomic DNA of 1-year-old SQS/ CaMKII-cre mutants, 39 ⫾ 3% of cortical cells were recombined. This value indicates that the vast majority of projection neurons was targeted (Ren et al., 1992). Neuronal survival, ...
Disc1Point Mutations in Mice Affect Development of the Cerebral
... Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5, and 8Institute of Membrane and Systems Biology, University of Leeds, Leeds LS2 9JT, United Kingdom ...
... Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5, and 8Institute of Membrane and Systems Biology, University of Leeds, Leeds LS2 9JT, United Kingdom ...
Enhanced Modulation of Neuronal Activity during
... neural mechanisms underlying volitional movement control. In this task, subjects suppress reflexive saccades to the sudden appearance of peripheral visual stimuli (prosaccades) and generate a saccade in the opposite direction. Recent imaging studies suggest that the globus pallidus (GP) is involved ...
... neural mechanisms underlying volitional movement control. In this task, subjects suppress reflexive saccades to the sudden appearance of peripheral visual stimuli (prosaccades) and generate a saccade in the opposite direction. Recent imaging studies suggest that the globus pallidus (GP) is involved ...
Fundamentals of Anatomy and Physiology, Second Edition
... – Lies inferior to the thalamus and attached by a small stalk to the pituitary gland – Controls and integrates autonomic nervous system – Receives sensory impulses from internal organs – Controls thirst, hunger, body temp, memory, emotion ( rage) and sleep – Controls pituitary gland and links endocr ...
... – Lies inferior to the thalamus and attached by a small stalk to the pituitary gland – Controls and integrates autonomic nervous system – Receives sensory impulses from internal organs – Controls thirst, hunger, body temp, memory, emotion ( rage) and sleep – Controls pituitary gland and links endocr ...
Richard Thompson
... William Prokasy, Allan Schrier, Joseph Sidowski, and James Voss. The graduate program then was Darwinian. I believe more than 30 began in my graduate class and 6 received their Ph.D. As was true of many others, my interests in brain substrates of memory were greatly stimulated by Donald Hebb's remar ...
... William Prokasy, Allan Schrier, Joseph Sidowski, and James Voss. The graduate program then was Darwinian. I believe more than 30 began in my graduate class and 6 received their Ph.D. As was true of many others, my interests in brain substrates of memory were greatly stimulated by Donald Hebb's remar ...
J Comp Neurol 2000 Lavenex - University of California, Berkeley
... the caching season, but did not coincide with either breeding season. In January, caching was completed but squirrels were still dependent on spatial memory to locate their caches; this period coincided with the first breeding season. In June, squirrels had depleted their caches and were not activel ...
... the caching season, but did not coincide with either breeding season. In January, caching was completed but squirrels were still dependent on spatial memory to locate their caches; this period coincided with the first breeding season. In June, squirrels had depleted their caches and were not activel ...
Mechanisms of excitability in the central and peripheral nervous
... function and in pathological conditions. For hippocampus the normal function includes changes in excitability linked to learning and memory. However, it also is intimately linked to pathological increases in excitability observed in epilepsy. In C–fibers, excitability controls sensitivity to respons ...
... function and in pathological conditions. For hippocampus the normal function includes changes in excitability linked to learning and memory. However, it also is intimately linked to pathological increases in excitability observed in epilepsy. In C–fibers, excitability controls sensitivity to respons ...
High baseline activity in inferior temporal cortex
... Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons ...
... Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons ...
Scene perception: inferior temporal cortex neurons encode the
... response was when the effective stimulus was in a parafoveal vs. a foveal position. The design of the experiments was to use a very wide range of stimuli in the different experiments with different neurons, so that any possible effects of the salience of any particular stimulus would not bias the re ...
... response was when the effective stimulus was in a parafoveal vs. a foveal position. The design of the experiments was to use a very wide range of stimuli in the different experiments with different neurons, so that any possible effects of the salience of any particular stimulus would not bias the re ...
Sprecher_2011_larval.. - Institute of Neuroinformatics
... left, dorsal up. A: Labeling with anti-Neuroglian (Ngl), showing neuronal cell bodies in cortex (co) and nerve processes, forming central neuropil (np). Z-projection of a confocal stack (3 μm). Added to the section is a 3D digital model (anterior view) of outer optic anlage (OOA, beige), inner optic ...
... left, dorsal up. A: Labeling with anti-Neuroglian (Ngl), showing neuronal cell bodies in cortex (co) and nerve processes, forming central neuropil (np). Z-projection of a confocal stack (3 μm). Added to the section is a 3D digital model (anterior view) of outer optic anlage (OOA, beige), inner optic ...
Mitochondrial support of persistent presynaptic vesicle mobilization
... perfusion-fixed (Figure 2E). It is unlikely that these spines simply retracted, leaving intact presynaptic boutons, because the frequency of nonsynaptic boutons did not increase (Figure 2E). The frequency of single synaptic boutons in the LTP condition was comparable to the perfusion-fixed and great ...
... perfusion-fixed (Figure 2E). It is unlikely that these spines simply retracted, leaving intact presynaptic boutons, because the frequency of nonsynaptic boutons did not increase (Figure 2E). The frequency of single synaptic boutons in the LTP condition was comparable to the perfusion-fixed and great ...
THE AREA POSTREMA: A POTENTIAL SITE FOR CIRCADIAN REGULATION BY
... ion substitution experiments revealed a PK2-induced Cl- current was responsible for membrane depolarization, while hyperpolarizations were the result of inhibition of an inwardly rectifying non-selective cation current. In contrast to these differential effects on membrane potential, nearly all neur ...
... ion substitution experiments revealed a PK2-induced Cl- current was responsible for membrane depolarization, while hyperpolarizations were the result of inhibition of an inwardly rectifying non-selective cation current. In contrast to these differential effects on membrane potential, nearly all neur ...
Inactivation of Parietal and Prefrontal Cortex Reveals
... of these subpopulations were matched to a greater extent (Chafee and Goldman-Rakic 1998) than could be gleaned from independent studies of the two populations using similar, but not identical, tasks (Andersen et al. 1990b; Bruce and Goldberg 1985; Funahashi et al. 1989 –1991; Gnadt and Andersen 1988 ...
... of these subpopulations were matched to a greater extent (Chafee and Goldman-Rakic 1998) than could be gleaned from independent studies of the two populations using similar, but not identical, tasks (Andersen et al. 1990b; Bruce and Goldberg 1985; Funahashi et al. 1989 –1991; Gnadt and Andersen 1988 ...
Novel approaches to explore mechanisms of
... highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. Novel treatment strategies are highly needed, as well as increased understanding of the hippoc ...
... highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. Novel treatment strategies are highly needed, as well as increased understanding of the hippoc ...
Structure-function relationship in hierarchical model of brain networks
... were examined. However, neural networks display several levels of topological organization that are not well-accounted for by such typical network models [105]. In addition, the oscillatory dynamics of neurons cannot be sufficiently described by low-dimensional oscillators, and synchronization behav ...
... were examined. However, neural networks display several levels of topological organization that are not well-accounted for by such typical network models [105]. In addition, the oscillatory dynamics of neurons cannot be sufficiently described by low-dimensional oscillators, and synchronization behav ...
5. Third year activities - LIRA-Lab
... evolved exclusively at the service of language. Accordingly, a cognitive translation into phonology is not necessary because the articulatory gestures are phonologic in nature. This elegant idea was however strongly debated at that time mostly because it was difficult to test, verification through t ...
... evolved exclusively at the service of language. Accordingly, a cognitive translation into phonology is not necessary because the articulatory gestures are phonologic in nature. This elegant idea was however strongly debated at that time mostly because it was difficult to test, verification through t ...
Enhanced Perceptual Functioning in Autism
... in autism, by making perceptual processes more difficult to control and more disruptive to the development of other behaviors and abilities. As a part of superior perceptual functioning, a superior perceptual trace was believed to be responsible for enhanced memory of the surface properties of visual ...
... in autism, by making perceptual processes more difficult to control and more disruptive to the development of other behaviors and abilities. As a part of superior perceptual functioning, a superior perceptual trace was believed to be responsible for enhanced memory of the surface properties of visual ...
Hippocampal mechanisms for the context-dependent retrieval of episodes 2005 Special issue
... Physiologically, this requires mechanisms for long-term storage and selective retrieval of episodes based on the time of occurrence, despite variable intervals and similarity of events in a familiar environment. Here, this process has been modeled based on the physiological properties of the hippoca ...
... Physiologically, this requires mechanisms for long-term storage and selective retrieval of episodes based on the time of occurrence, despite variable intervals and similarity of events in a familiar environment. Here, this process has been modeled based on the physiological properties of the hippoca ...
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... regarded as involving mild morphological, biochemical and physiological changes, which lead to slowing down of the normal function of the nervous system. The results of pathological aging are the neurodegenerative diseases, defined as progressive loss of neurons and extensive deterioration of cognit ...
... regarded as involving mild morphological, biochemical and physiological changes, which lead to slowing down of the normal function of the nervous system. The results of pathological aging are the neurodegenerative diseases, defined as progressive loss of neurons and extensive deterioration of cognit ...
Severely dystrophic axons at amyloid plaques
... sagittal sections of frontal, parietal and occipital cortex and plaques counted and measured within it (excluding satellite plaques). Temporal cortex was excluded from this analysis as axons in this region cannot be followed back to their cell bodies. The diameter of the plaques (single line measure ...
... sagittal sections of frontal, parietal and occipital cortex and plaques counted and measured within it (excluding satellite plaques). Temporal cortex was excluded from this analysis as axons in this region cannot be followed back to their cell bodies. The diameter of the plaques (single line measure ...
Smell, Taste, Texture, and Temperature
... Five Prototypical Tastes, Including Umami. In the primary and secondary taste cortex, there are many neurons that respond best to each of the four classical prototypical tastes—sweet, salt, bitter, and sour5— but there are also many neurons that respond best to umami tastants such as glutamate (whi ...
... Five Prototypical Tastes, Including Umami. In the primary and secondary taste cortex, there are many neurons that respond best to each of the four classical prototypical tastes—sweet, salt, bitter, and sour5— but there are also many neurons that respond best to umami tastants such as glutamate (whi ...
Shootin1 - The Journal of Cell Biology
... The basic function of neurons is to receive, integrate, and transmit signals. To do so, most neurons develop polarity by forming a single axon and multiple dendrites (Craig and Banker, 1994; Winckler and Mellman, 1999; Da Silva and Dotti, 2002; Horton and Ehlers, 2003). Neurons have the remarkable a ...
... The basic function of neurons is to receive, integrate, and transmit signals. To do so, most neurons develop polarity by forming a single axon and multiple dendrites (Craig and Banker, 1994; Winckler and Mellman, 1999; Da Silva and Dotti, 2002; Horton and Ehlers, 2003). Neurons have the remarkable a ...
The effect of spinal cord injury on the neurochemical properties of
... complications such as bladder, bowel and sexual dysfunction affect health and quality of ...
... complications such as bladder, bowel and sexual dysfunction affect health and quality of ...
The cognitive neuroscience of sustained attention
... the assessment of sustained attention (or vigilance) performance typically has utilized situations in which an observer is required to keep watch for inconspicuous signals over prolonged periods of time. The state of readiness to respond to rarely and unpredictably occurring signals is characterized ...
... the assessment of sustained attention (or vigilance) performance typically has utilized situations in which an observer is required to keep watch for inconspicuous signals over prolonged periods of time. The state of readiness to respond to rarely and unpredictably occurring signals is characterized ...
Structure and Function of Visual Area MT
... extrastriate, motion perception, center-surround antagonism, magnocellular, structure-from-motion, aperture problem ...
... extrastriate, motion perception, center-surround antagonism, magnocellular, structure-from-motion, aperture problem ...