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Chapter 12
Chapter 12

... B. DNA Replication Steps: 1. Helicase: unwinds the helix 2. Binding proteins help to stabilize the DNA strands at replication fork. 3. Primase primes the DNA strand for synthesis. 4. DNA Polymerase adds on many nucleotide monomers for Go to Section: elongation. ...
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ch 12 jeopardy review Molecular Genetics

... 2. Guanine to Cytosine Cytosine to Guanine ...
The Structure of DNA DNA Has the Structure of a Winding Staircase
The Structure of DNA DNA Has the Structure of a Winding Staircase

... • Each strand is composed of nucleotides. • Nucleotides are the subunits that make up DNA. • Made of 3 parts: phosphate group, deoxyribose (sugar) & a nitrogen base. ...
GENETICS 603 Outline and Key Topics for Lecture 1 DNA
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... 1953 Watson and Crick published the "double helix" model of DNA in which two strands, running in opposite directions, were held together by Hydrogen bonds between the base pairs A and T, and G and C. The base pairs are in the center of the molecule like the steps of a spiral staircase, with the phos ...
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... around each other like coils • Angle of the X shows there are 2 strands ...
Griffith`s Experiment (1928)
Griffith`s Experiment (1928)

... Base pairing allows each strand to serve as a pattern for a new strand  Semi-conservative replication: parent DNA strands serve as a template for replication  daughter DNA is composed of one parent strand and one new one  Large team of enzymes coordinates replication ...
DNA: Replication and Mutation
DNA: Replication and Mutation

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Hein and Arena - University of Wisconsin–Eau Claire
Hein and Arena - University of Wisconsin–Eau Claire

... • In DNA, secondary structure pertains to the helix formed by the interaction of two DNA strands. • In the most commonly found form of DNA, two single strands lie side by side in an antiparallel arrangement, with one running 5’ to 3’ and the other running 3’ to 5’. • The two DNA strands are held to ...
Hein and Arena - chem.uwec.edu
Hein and Arena - chem.uwec.edu

... • In DNA, secondary structure pertains to the helix formed by the interaction of two DNA strands. • In the most commonly found form of DNA, two single strands lie side by side in an antiparallel arrangement, with one running 5’ to 3’ and the other running 3’ to 5’. • The two DNA strands are held to ...
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DNA Model and Replication Name: Objective: The students will

... 3. How does the model you constructed differ from an actual DNA molecule, besides being made of candy? 4. Describe how the replication process creates two exact copies. ...
Lab 8H - Constructing A Model of DNA Replication PDF
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... DNA is a large molecule made out of two long, parallel strands of nucleotides twisted around each other to form a double helix. Each nucleotide is composed of a sugar, deoxyribose, bonded to a phosphate and nitrogen base. There are four nitrogen bases, adenine, guanine, cytosine, and thymine. The or ...
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AP Biology - HPHSAPBIO
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... 4. Describe the semiconservative model of replication and the significance of the experiments by Matthew Meselson and Franklin Stahl. 5. Describe the process of DNA replication. Note the structure of the many origins of replication and replication forks and explain the role of DNA polymerase. 6. Def ...
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... E) none of the above 20. During your summer job at Virotech, you isolate a previously unknown virus. Analysis of its genome reveals that it is composed of a double stranded DNA molecule containing 14% T (thymine). Based on this information, what would you predict the %C (cytosine) to be? A) 14% B) 2 ...
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BIOLOGY Chapter 11: DNA and the Language of Life Name: Section
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... 2. DNA polymerase Concept 11.3: DNA replication is the molecular mechanism of inheritance. DNA replication is the process of copying the DNA molecule. During DNA copying, the two strands of the double helix separate. Each single strand acts as a “negative” or “template” for producing a new, compleme ...
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... 2. Briefly describe how Watson and Crick came to the discovery of the double helix structure of DNA. ...
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Eukaryotic DNA replication



Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to only once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded templates. Replication processes permit the copying of a single DNA double helix into two DNA helices, which are divided into the daughter cells at mitosis. The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes, but the replication machinery in eukaryotic DNA replication is a much larger complex, coordinating many proteins at the site of replication, forming the replisome.The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. This process allows for the high-fidelity passage of hereditary/genetic information from parental cell to daughter cell and is thus essential to all organisms. Much of the cell cycle is built around ensuring that DNA replication occurs without errors.In G1 phase of the cell cycle, many of the DNA replication regulatory processes are initiated. In eukaryotes, the vast majority of DNA synthesis occurs during S phase of the cell cycle, and the entire genome must be unwound and duplicated to form two daughter copies. During G2, any damaged DNA or replication errors are corrected. Finally, one copy of the genomes is segregated to each daughter cell at mitosis or M phase. These daughter copies each contain one strand from the parental duplex DNA and one nascent antiparallel strand.This mechanism is conserved from prokaryotes to eukaryotes and is known as semiconservative DNA replication. The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporationof free nucleotides into double-stranded DNA.
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