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DNA Mutation Consequences
DNA Mutation Consequences

... Mutations are changes in a DNA sequence. A point mutation is a change in a single base pair of a gene. Point mutations, or single nucleotide polymorphisms (SNPs), involve only one nitrogen base change of the three nitrogen bases in a codon. Perform this activity and witness the change a single point ...
Chapter 16: DNA: The Genetic Material
Chapter 16: DNA: The Genetic Material

... 1. the genetic material must be able to replicate itself 2. must be able to control living processes B. a model of genetic inheritance was in place in the early 1900s: 1. Mendel’s “laws” of genetics – inherit one copy of each gene from each parent 2. chromosomes as locations/carriers of genes 3. dis ...
DNA powerpoint
DNA powerpoint

... • RNA is a single-stranded nucleic acid that has a similar structure to that of DNA (chain of nucleotides attached by the sugar and phosphate groups). However, RNA’s sugar is ribose. • The four nucleotide bases are adenine, guanine, cytosine, and uracil. In RNA, uracil replaces thymine (a DNA nucleo ...
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry

... pairs. RNA-RNA double helices and DNA-RNA hybrid double helices melt at higher temperatures than double-helical DNAs of comparable base composition, for unknown reasons. ...
PCR/GMO Worksheet
PCR/GMO Worksheet

... 1. What materials are necessary to place in a PCR reaction? How are primers designed to assure that a specific gene (or DNA sequence) is amplified? ...
DNA and Replication RNA and Transcription Translation
DNA and Replication RNA and Transcription Translation

... 2. If “start” codon (= AUG) is read, the ribosome begins to read the mRNA 1 codon at a time. 3. tRNA’s deliver amino acids to the ribosome – peptide bonds links amino acids together. 4. Polypeptide chain of amino acids is released when a “stop” codon is read. 5. Polypepide chain folds into its 3-D s ...
Chapter 12 DNA and RNA
Chapter 12 DNA and RNA

... with bacteria and virus to find out if protein or DNA held genes • Virus = DNA/RNA surrounded by a protein coat • Bacteriophage = a virus that infects bacteria ...
12.1 and 12.2 Fill
12.1 and 12.2 Fill

... 2. This allows to the two strands to _________ and unwind.  Because each original strand can be used to make a new strand, the strands are said to be complementary. 3. Each strand of the double helix of DNA serves as a ____________, or model, for the new strand. 4. The enzyme ________ polymerase he ...
Test Review Sheet - Lyndhurst Schools
Test Review Sheet - Lyndhurst Schools

... 28) The amount of DNA material required for STR analysis is ________ the amount of DNA required for RFLP analysis. A) greater than B) the same as C) less than 29. Can PCR be performed on STRs or RFLPs? ______________ Why? __________________________ ...
Principle of Distance Measurement: Förster Resonance Energy
Principle of Distance Measurement: Förster Resonance Energy

... *Evan Evans, 2002 & Netz, Neutral and Charged Polymers at Interfaces ...
Slide 1
Slide 1

... catalyzes the reaction in which a. the double helix unwinds. b. the sugar-phosphate bonds of each strand are broken. c. a phosphate group is added to the 3’-carbon or 5’carbon of ribose. d. a nucleotide with a base complementary to the base on the template strand is added to the new DNA strand. e. t ...
DNA: The Genetic Material
DNA: The Genetic Material

... deoxyribose nucleic acid: it contains a sugar moiety (deoxyribose), it is weakly acidic, and is found in the nucleus. ...
http://www.councilforresponsiblegenetics.org/genewatch
http://www.councilforresponsiblegenetics.org/genewatch

... pigmentation alleles. The AIMs technology, (again, packaged with different names depending on the market and client) as manufactured by DNAPrint Genomics, is specifically designed to assess allelic frequency differences of coding DNA, or Single Nucleotide Polymorphisms. This is important, since mark ...
Exhaustive search - University of Illinois at Urbana
Exhaustive search - University of Illinois at Urbana

... Looking for differentially expressed genes • Measure the activity level of all genes in normal fly and in infected fly • Find genes whose activity levels are significantly different between the two conditions • How to measure gene activity level ? ...
Unit 3: CHEMICAL PRINCIPLES:
Unit 3: CHEMICAL PRINCIPLES:

... slightly altered base-pairing properties. Some antiviral and antitumor drugs are base ...
From DNA to Protein
From DNA to Protein

...  Proteins are made in the cytoplasm and then work to keep the cell alive  Translation (protein synthesis): Process of making a protein  Proteins are made up of amino acids (small building blocks)  There are 20 different types of amino acids Protein ...
DNA - Fort Thomas Independent Schools
DNA - Fort Thomas Independent Schools

... Mutation  a change in the DNA sequence  It’s a mistake that’s made during replication or transcription  can be harmful: diseases or deformities helpful: organism is better able to survive neutral: organism is unaffected  if a mutation occurs in a sperm or egg cell, that mutation is ...
1. To research…
1. To research…

... percent of those bases are the same in all people. The order, or sequence, of these bases determines the information available for building and maintaining an organism, similar to the way in which letters of the alphabet appear in a certain order to form words and sentences. DNA bases pair up with e ...
DNA- The Molecule of Heredity
DNA- The Molecule of Heredity

... 1. The structure of a DNA molecule can be described as a _____. 2. During DNA replication, the DNA molecule ______ into two strands. 3. DNA looks like a twisted ladder. Which parts of a twisted ladder represent the hydrogen bonds and the sugar-phosphate ...
DNA & RNA Notes
DNA & RNA Notes

... Gel Electrophoresis: Process that involves using electric current to separate certain biological molecules by size. We use this to see DNA fragments to create a DNA fingerprint - DNA fingerprints have 2 major uses: 1.Solve crimes 2.Figuring out “who’s the baby’s daddy” ...
Nucleic Acids notes
Nucleic Acids notes

... How is that possible? (a) Often true in 3rd position of a codon, especially transitions. The change doesn Modify the codon to produce a different AA ( single- nucleotide polymorphism (SNP) specif The same AA. (b) May terminate protein synthesis by introducing a stop codon. the genetic code is degene ...
DNA - canesbio
DNA - canesbio

... B. Intron – interrupting noncoding sequences of DNA does not code for protein C. mRNA strand – introns cut out, so only exons left ...
Central Dogma of Molecular Biology
Central Dogma of Molecular Biology

... Transcription: when DNA is copied onto a complementary strand of mRNA  Translation: the construction of a protein from the instructions of the mRNA. This happens at the ribosomes in the cytoplasm. Here mRNA codons match with tRNA anticodons to bring amino acids.  Codon: a sequence of 3 nucleotides ...
2013 DNA/Replication Notes
2013 DNA/Replication Notes

... DNA. In particular, it could be determined from the diffraction pattern, and was openly discussed by Franklin in lectures attended by Watson and in reports accessible to Watson and Crick, that DNA (1) was helical, (2) was likely a double helix with antiparallel strands, and, (3) had the phosphate ba ...
Click to add title
Click to add title

... • Discovered a protein-like composition of nucleins • Also a non-protein component: ...
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DNA nanotechnology



DNA nanotechnology is the design and manufacture of artificial nucleic acid structures for technological uses. In this field, nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells. Researchers in the field have created static structures such as two- and three-dimensional crystal lattices, nanotubes, polyhedra, and arbitrary shapes, as well as functional devices such as molecular machines and DNA computers. The field is beginning to be used as a tool to solve basic science problems in structural biology and biophysics, including applications in crystallography and spectroscopy for protein structure determination. Potential applications in molecular scale electronics and nanomedicine are also being investigated.The conceptual foundation for DNA nanotechnology was first laid out by Nadrian Seeman in the early 1980s, and the field began to attract widespread interest in the mid-2000s. This use of nucleic acids is enabled by their strict base pairing rules, which cause only portions of strands with complementary base sequences to bind together to form strong, rigid double helix structures. This allows for the rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features. A number of assembly methods are used to make these structures, including tile-based structures that assemble from smaller structures, folding structures using the DNA origami method, and dynamically reconfigurable structures using strand displacement techniques. While the field's name specifically references DNA, the same principles have been used with other types of nucleic acids as well, leading to the occasional use of the alternative name nucleic acid nanotechnology.
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