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DNA & Proteins

... A DNA mutation changes the amino acid sequence and so a different protein may be produced. ...
Chapter 17: Transcription, RNA Processing, and Translation
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... Lecture 22 “Transcription of Genes: Production of RNA” Review: 1.) What is the function of RNA Polymerase? What is the template strand and what is the coding strand? What direction does RNA Polymerase perform its template-directed synthesis (strand polarity here)? 2.) Does RNA Polymerase require a p ...
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... 2. Frameshift mutations: bases are inserted or deleted  Are usually harmful because a mistake in DNA is carried into mRNA and results in many wrong amino acids Correct DNA: ...
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DNA polymerase



The DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two identical DNA strands from a single original DNA molecule. During this process, DNA polymerase “reads” the existing DNA strands to create two new strands that match the existing ones.Every time a cell divides, DNA polymerase is required to help duplicate the cell’s DNA, so that a copy of the original DNA molecule can be passed to each of the daughter cells. In this way, genetic information is transmitted from generation to generation.Before replication can take place, an enzyme called helicase unwinds the DNA molecule from its tightly woven form. This opens up or “unzips” the double-stranded DNA to give two single strands of DNA that can be used as templates for replication.
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