Jane Stewart`s CV - Concordia University
... Davis, M.A., Winthrop, S.O., Stewart, J., Sunahara, F.A., & Herr, F. New psychotropic agents. V. Derivatives of 5-‐ cyano-‐ and 5-‐carboxamido-‐dibenzo(a,d)cycloheptadiene. Journal of Medicinal Chemistry, 196 ...
... Davis, M.A., Winthrop, S.O., Stewart, J., Sunahara, F.A., & Herr, F. New psychotropic agents. V. Derivatives of 5-‐ cyano-‐ and 5-‐carboxamido-‐dibenzo(a,d)cycloheptadiene. Journal of Medicinal Chemistry, 196 ...
Elicited hippocampal theta rhythm: a screen for anxiolytic and
... theta frequency; and to avoid pathways that can modulate or gate theta but that do not normally contribute to frequency. The focus of the review is on elicited theta, also, because with spontaneously occurring theta, apparent effects of drugs on theta could be indirect effects of the drugs on behavi ...
... theta frequency; and to avoid pathways that can modulate or gate theta but that do not normally contribute to frequency. The focus of the review is on elicited theta, also, because with spontaneously occurring theta, apparent effects of drugs on theta could be indirect effects of the drugs on behavi ...
Chapter 32 Airway Pharmacology
... combined anticholinergic & -agonist • Ipratropium bromide & albuterol (Combivent, Duoneb) is indicated for patients with COPD or asthma ...
... combined anticholinergic & -agonist • Ipratropium bromide & albuterol (Combivent, Duoneb) is indicated for patients with COPD or asthma ...
Meloxicam (Mobic) - Texas Department of State Health Services
... movement, global efficacy and paracetamol consumption, although differences were not statistically significant. GI adverse effects occurred in both groups, however, there was a higher incidence (26 vs. 16%) of GI adverse events in the diclofenac group compared to meloxicam group.7 Wojtulewski et al ...
... movement, global efficacy and paracetamol consumption, although differences were not statistically significant. GI adverse effects occurred in both groups, however, there was a higher incidence (26 vs. 16%) of GI adverse events in the diclofenac group compared to meloxicam group.7 Wojtulewski et al ...
PRODUCT MONOGRAPH Pr INDERAL®-LA (Propranolol
... larger doses of epinephrine may be needed to overcome the bronchospasm, while on the other, these doses can be associated with excessive alpha adrenergic stimulation with consequent hypertension, reflex bradycardia and heart block and possible potentiation of bronchospasm. Alternatives to the use of ...
... larger doses of epinephrine may be needed to overcome the bronchospasm, while on the other, these doses can be associated with excessive alpha adrenergic stimulation with consequent hypertension, reflex bradycardia and heart block and possible potentiation of bronchospasm. Alternatives to the use of ...
Morphine - ISpatula
... *it can be metabolized partially by liver enzymes (de-methylated) to produce morphine so it produces morphine-like analgesic effects but little euphoria. *it's about one –tenth (1/10) the potency of morphine. So, relatively it is a safe non-addictive medium analgesic –for sure- when used within th ...
... *it can be metabolized partially by liver enzymes (de-methylated) to produce morphine so it produces morphine-like analgesic effects but little euphoria. *it's about one –tenth (1/10) the potency of morphine. So, relatively it is a safe non-addictive medium analgesic –for sure- when used within th ...
residence times and half-lives of nicotine metabolites in rat brain
... supernatants from five animals that had each been administered 0.8 mg/kg of nonradiolabeled S(2)-nicotine 4 h earlier were pooled and processed, and the extract was injected onto the GC-MS. Figure 2 illustrates the GC chromatograph of this extract. Nicotine and the three metabolites, nornicotine, co ...
... supernatants from five animals that had each been administered 0.8 mg/kg of nonradiolabeled S(2)-nicotine 4 h earlier were pooled and processed, and the extract was injected onto the GC-MS. Figure 2 illustrates the GC chromatograph of this extract. Nicotine and the three metabolites, nornicotine, co ...
Atarax™
... system (see Section Adverse Reactions). In children, convulsions have been more frequently reported than in adults. Hydroxyzine anticholinergic effects Because of its potential anticholinergic effects, ATARAX should be used cautiously in patients suffering from glaucoma, bladder outflow obstruction, ...
... system (see Section Adverse Reactions). In children, convulsions have been more frequently reported than in adults. Hydroxyzine anticholinergic effects Because of its potential anticholinergic effects, ATARAX should be used cautiously in patients suffering from glaucoma, bladder outflow obstruction, ...
article in press
... the search for new atypical antipsychotics presenting low cost and the understanding of the mechanism of action leading to atypical antipsychotic profile. The results obtained are presented in two distinct parts based on their nature, namely, experimental (first part) or theoretical (second part). F ...
... the search for new atypical antipsychotics presenting low cost and the understanding of the mechanism of action leading to atypical antipsychotic profile. The results obtained are presented in two distinct parts based on their nature, namely, experimental (first part) or theoretical (second part). F ...
Recent advances in knowledge about beta
... beta-receptors was not revealed until the advent of radiolabeled ligand binding studies. This biochemical approach has confirmed directly the existence of two subtypes of betaadrenergic receptors (20,26-28) and more recently suggested that the molecular properties of beta,- and betar receptors proba ...
... beta-receptors was not revealed until the advent of radiolabeled ligand binding studies. This biochemical approach has confirmed directly the existence of two subtypes of betaadrenergic receptors (20,26-28) and more recently suggested that the molecular properties of beta,- and betar receptors proba ...
Dopamine, behavioral economics, and effort
... cost is too high), the animal reaches the point at which additional responses being required actually tend to suppress responding. For normal rats, responding at levels of FR64, FR100 or higher, even if there is only one 45 mg food pellet being delivered, does not seem to be problematic. A completel ...
... cost is too high), the animal reaches the point at which additional responses being required actually tend to suppress responding. For normal rats, responding at levels of FR64, FR100 or higher, even if there is only one 45 mg food pellet being delivered, does not seem to be problematic. A completel ...
evaluation of antidepressant like activity of curcumin and its
... diameter: 15 cm; containing 15 cm hight of water maintained at 25 ± 1OC). Mice placed in the cylinder for the first time were initially highly active, vigorously swimming in circles, trying to climb the wall or diving to the bottom. After 2ñ3 min, activity began to subside and was interspersed with ...
... diameter: 15 cm; containing 15 cm hight of water maintained at 25 ± 1OC). Mice placed in the cylinder for the first time were initially highly active, vigorously swimming in circles, trying to climb the wall or diving to the bottom. After 2ñ3 min, activity began to subside and was interspersed with ...
Drug Abuse Warning Network, 2005: National
... system that monitors drug-related ED visits for the Nation and for selected metropolitan areas. DAWN estimates pertain to the entire United States, including Alaska, Hawaii, and the District of Columbia. The Substance Abuse and Mental Health Services Administration (SAMHSA) is the agency responsible ...
... system that monitors drug-related ED visits for the Nation and for selected metropolitan areas. DAWN estimates pertain to the entire United States, including Alaska, Hawaii, and the District of Columbia. The Substance Abuse and Mental Health Services Administration (SAMHSA) is the agency responsible ...
Medication Guide
... Sudden deaths, stroke, and myocardial infarction have been reported in adults taking stimulant drugs at usual doses for ADHD. Although the role of stimulants in these adult cases is also unknown, adults have a greater likelihood than children of having serious structural cardiac abnormalities, cardi ...
... Sudden deaths, stroke, and myocardial infarction have been reported in adults taking stimulant drugs at usual doses for ADHD. Although the role of stimulants in these adult cases is also unknown, adults have a greater likelihood than children of having serious structural cardiac abnormalities, cardi ...
File - Ms. Walajtys` Pharmacy Tech Class Sidekick
... • Reduces release of neurotransmitters glutamate, norepinephrine, substance P • Similar to gabapentin, more potent. Fewer side effects than other anticonvulsants • Controlled substance, Schedule V • Also approved to treat diabetic neuropathy ...
... • Reduces release of neurotransmitters glutamate, norepinephrine, substance P • Similar to gabapentin, more potent. Fewer side effects than other anticonvulsants • Controlled substance, Schedule V • Also approved to treat diabetic neuropathy ...
Triptans - Consumer Health Choices
... If sumatriptan doesn’t work for you, we recommend trying rizatriptan (Maxalt and generic). Studies indicate it works very well in delivering pain relief within two hours compared with many of the other triptans. But it may be more expensive. The cost for triptan treatment depends on how often you ha ...
... If sumatriptan doesn’t work for you, we recommend trying rizatriptan (Maxalt and generic). Studies indicate it works very well in delivering pain relief within two hours compared with many of the other triptans. But it may be more expensive. The cost for triptan treatment depends on how often you ha ...
2002
... the absence and presence of 10M naloxone. The potency of the drugs in displacing the specific binding of the 3Hligand is determined from data using Graphpad Prism (GraphPAD, San Diego, CA) and converted to Ki values by the method of Cheng and Prussoff (1973). Opioid binding is performed in membrane ...
... the absence and presence of 10M naloxone. The potency of the drugs in displacing the specific binding of the 3Hligand is determined from data using Graphpad Prism (GraphPAD, San Diego, CA) and converted to Ki values by the method of Cheng and Prussoff (1973). Opioid binding is performed in membrane ...
Cannabis Do You Know... What is it?
... At low doses, cannabis mildly distorts perception and the senses. People who use the drug say that it makes music sound better, colours appear brighter and moments seem longer. They say that it enhances taste, touch and smell and makes them feel more aware of their body. Some enjoy these effects, b ...
... At low doses, cannabis mildly distorts perception and the senses. People who use the drug say that it makes music sound better, colours appear brighter and moments seem longer. They say that it enhances taste, touch and smell and makes them feel more aware of their body. Some enjoy these effects, b ...
the 2014 drug trend report
... In 2013 and 2014, spend for compound medications escalated rapidly. Compounded drugs now rank as the third-most-expensive therapy class on a PMPY basis, displacing high blood pressure medications, which had ranked among the top three most-expensive traditional therapy classes for at least a decade. ...
... In 2013 and 2014, spend for compound medications escalated rapidly. Compounded drugs now rank as the third-most-expensive therapy class on a PMPY basis, displacing high blood pressure medications, which had ranked among the top three most-expensive traditional therapy classes for at least a decade. ...
Tobacco Smoking and Nicotine Neuropsychopharmacology
... A total of 1,953 tobacco smokers were examined for quit rates between nicotine replacement and placebo treated groups. The 4-week quit rates were 37.2% for the nicotine treated versus 22.1% for the placebo group (p , .0001). After 12 months, the quit rates were 14.9% for the nicotine and 11.1% for t ...
... A total of 1,953 tobacco smokers were examined for quit rates between nicotine replacement and placebo treated groups. The 4-week quit rates were 37.2% for the nicotine treated versus 22.1% for the placebo group (p , .0001). After 12 months, the quit rates were 14.9% for the nicotine and 11.1% for t ...
Dopamine, Locus of Control, and the Exploration
... but not exploitative, behavior in Met/Met rather than Val/Val subjects. Independent of genotype, those subjects with a more external LOC also showed increases in uncertainty-driven exploration on tolcapone relative to placebo. However, we did not replicate our previous finding that Met/Met subjects ...
... but not exploitative, behavior in Met/Met rather than Val/Val subjects. Independent of genotype, those subjects with a more external LOC also showed increases in uncertainty-driven exploration on tolcapone relative to placebo. However, we did not replicate our previous finding that Met/Met subjects ...
Adrenergic-Blocking Drugs
... prevent or minimize postural hypotension Avoid caffeine (excessive irritability) Avoid alcohol ingestion and hazardous activities until blood levels become stable Patients should notify their physician if palpitations, dyspnea, nausea, or vomiting occurs ...
... prevent or minimize postural hypotension Avoid caffeine (excessive irritability) Avoid alcohol ingestion and hazardous activities until blood levels become stable Patients should notify their physician if palpitations, dyspnea, nausea, or vomiting occurs ...
piracetam and platelets
... acetylcholine/glutamate neuroactivity. In spite of these effects, piracetam is generally not considered to be a significant agonist or inhibitor of the synaptic action of most neurotransmitters. The piracetam-type nootropic drugs might exert their effect on some species of molecules present in the p ...
... acetylcholine/glutamate neuroactivity. In spite of these effects, piracetam is generally not considered to be a significant agonist or inhibitor of the synaptic action of most neurotransmitters. The piracetam-type nootropic drugs might exert their effect on some species of molecules present in the p ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.