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Stroke volume increase to exercise in chronic - VU-DARE
Stroke volume increase to exercise in chronic - VU-DARE

... subsequent rise in Ppa on cardiac function have shown that right ventricular end-diastolic volume (RVEDV) increases5 6 and right ventricular ejection fraction (RVEF) fails to augment to exercise in most COPD patients.7–10 Right ventricular dilatation and a consequent unaltered RVEF, however, do not ...
Human Heart Weight at High Altitude
Human Heart Weight at High Altitude

... of high altitude (12,300 feet) residents in Peru and in 86 hearts from sea level in the continental United States revealed that right ventricular hypertrophy is no greater at high altitude than at sea level in the stillborn-newborn infant heart. Right ventricular weight relative to total heart weigh ...
DOI: 10.1161/CIRCULATIONAHA.106.661983 published online Jul
DOI: 10.1161/CIRCULATIONAHA.106.661983 published online Jul

... eart failure is a common cardiovascular syndrome that may occur in conjunction with either normal or abnormal left ventricular (LV) ejection fraction (EF). Patients with reduced EF have predominantly systolic dysfunction, whereas those with heart failure symptoms despite normal EF (HFNEF) are though ...
Acquired Heart Diseases - Akademija nauka i umjetnosti Bosne i
Acquired Heart Diseases - Akademija nauka i umjetnosti Bosne i

... Endomyocardial biopsy is a criterion for differential diagnosis in a patient with dilated cardiomyopathy. It is performed in circumstances of: unexplainable heart failure within two weeks, with or without LV dilatation; suspected fulminant or giant cell myocarditis; patients who do not respond to th ...
Echocardiographic Left Ventricular Mass Index Predicts
Echocardiographic Left Ventricular Mass Index Predicts

... evaluations, have undergone echocardiography during the third examination (1993–1995), and have been followed up for incident cardiovascular disease including ischemic stroke. Results—The study population consisted of 1792 participants, of whom 639 (35.7%) were men and the mean⫾SD age was 58.8⫾5.7 y ...
The Fontan Circulation: The Known, the Unknown and
The Fontan Circulation: The Known, the Unknown and

... The role of bosentan in the treatment of patients with a Fontan circulation is still unclear. In patients with pulmonary arterial hypertension (PAH), therapy with bosentan, an endothelin-1 receptor antagonist, has demonstrated to improve exercise capacity and to reduce the elevated PVR. An improveme ...
Heart failure causes cholinergic transdifferentiation of cardiac
Heart failure causes cholinergic transdifferentiation of cardiac

... were strongly upregulated in the ventricles of rats with CHF. Further, LIF and cardiotrophin-1 secreted from cultured failing rat cardiomyocytes induced cholinergic transdifferentiation in cultured sympathetic neurons, and this process was reversed by siRNAs targeting Lif and cardiotrophin-1. Consis ...
Acutely Decompensated Heart Failure: Diagnostic and Therapeutic
Acutely Decompensated Heart Failure: Diagnostic and Therapeutic

... Volume overload combined with poor left ventricular performance results in gradual worsening of congestive symptoms. Patients with ADHF due primarily to systemic volume overload will often describe a slow increase in lower extremity edema, dyspnea, and fatigue. Acute diastolic dysfunction results in ...
Effects of Sodium Nitroprusside on Left Ventricular Diastolic
Effects of Sodium Nitroprusside on Left Ventricular Diastolic

... cineangiography, as described below, but did not receive sodium nitroprusside. Two of these patients had severe congestive cardiomyopathy thought to be secondary to alcohol abuse, one patient had aortic stenosis and insufficiency with congestive heart failure due to congenital heart disease and thre ...
Use of Alternating Current During Diagnostic
Use of Alternating Current During Diagnostic

... SUMMARY When conventional programmed electrical stimulation did not yield ventricular arrhythmias suitable for testing implanted automatic defibrillator function and for mapping the location of arrhythmogenic foci, full-wave rectified alternating current (120 Hz) was used for inducing arrhythmias. A ...
Stroke Volume Dynamics During Progressive Exercise in Healthy
Stroke Volume Dynamics During Progressive Exercise in Healthy

... the heart as the primary controller of circulatory flow is not, however, consistent with the cardiovascular responses observed during endurance exercise (37). Data initially obtained from studies in animals and humans in the 1950s indicated that facilitation and control of blood flow during such exe ...
Prognostic Implications of Left Ventricular Mass and Geometry
Prognostic Implications of Left Ventricular Mass and Geometry

... VALIANT study: age (in years), primary percutaneous transluminal coronary angioplasty, atrial fibrillation complicating MI, history of diabetes, history of hypertension, prior MI, Killip class, history of congestive heart failure, new left bundle branch block, history of angina, LVEF, estimated glom ...
the mechanism of the nervous regulation of the crayfish heart
the mechanism of the nervous regulation of the crayfish heart

... longer period, acceleration cannot induce it to reach its former maximum, nor can a heart which is beating relatively slowly be speeded up to the same frequency which a heart, beating normally at a higher rate, can reach. As with inhibition, the accelerating effect diminishes during prolonged stimul ...
Right ventricular aneurysm with - Heart
Right ventricular aneurysm with - Heart

... myocardial infarction. Arrhythmias happen some- No abnormal cardiac pulsations were noted on the chest times as complications of left ventricular aneurysm, wall. On auscultation, the second heart sound split and aneurysmectomy for the control of these normally during inspiration and no significant m ...
Single Ventricle Palliation: Stage One Reconstruction
Single Ventricle Palliation: Stage One Reconstruction

... (74% vs 64%) – Really?????? Ohye RG et al. N Engl J Med 2010;362:1980-1992. ...
Polar S810 as an Alternative Resource to the Use of the
Polar S810 as an Alternative Resource to the Use of the

... complex (ventricular depolarization), regardless of whether this was determined by a normal beat originated in the sinus node or by a ventricular premature beat. Therefore, the occurrence of ventricular premature beats during the T4s may limit the interpretation of the RR intervals by the HMR. In ou ...
Pacemaker activity in an insect heart
Pacemaker activity in an insect heart

... aorta (Fig. 2B). There was always a 1:1 relationship between the aortic CAP and a contraction of the aorta (Fig. 2C). In other experiments, when the preparation was left to settle for over an hour, the relationship between the pacemaker action potential recorded from the first cardiac segment and th ...
Effects of positive-pressure ventilation on the spontaneous
Effects of positive-pressure ventilation on the spontaneous

... cardiovascular control. Changes in respiratory patterns, during hyperventilation for example, influence cardiac and vascular function not only by changes in blood gas chemistry, but also by modulating neural circulatory control mechanisms (42). The significance of these interactions in conditions of ...
Methodology of monitoring cardiovascular regulation
Methodology of monitoring cardiovascular regulation

... of the CV regulation is still controversial. Oosting et al. 41, include in BRS index calculation all BP sequences, nonbaroreflex sequences as well, regardless the direction of HP changes with respect to pressure changes. The idea behind this approach is that the relationship between HP and arterial ...
- Austin Publishing Group
- Austin Publishing Group

... aetiology, with well-studied hereditary transmission in some population subgroups. It is characteristically associated with gene mutations of desmosomal myocardial proteins (plakoglobin, desmoplakin, plakophilin-2, desmoglein-2 and desmocollin-2, etc.) conditioning abnormalities in the intercellular ...
Recurrence of Left Ventricular Dysfunction in Patients With Restored
Recurrence of Left Ventricular Dysfunction in Patients With Restored

... confirmed by echocardiography according to the recommendations by the American Society of Echocardiography.5 LV dysfunction was defined as an ejection fraction (EF) <40% by echocardiography. Coronary angiography or coronary multidetector computed tomography (MDCT) was performed to exclude LV dysfunc ...
Reservoir and Conduit Function of the Right Atrium - AJP
Reservoir and Conduit Function of the Right Atrium - AJP

... The right atrium is a dynamic structure whose role is to assist filling of the right ventricle. Ideally, the right atrium should transfer a high volume of blood rapidly to the ventricle at low pressure to prevent peripheral edema and hepatic congestion. The three components of atrial function are: 1 ...
COMPUTATIONAL MECHANICS TOWARDS IMPROVED UNDERSTANDING OF THE BIOMECHANICS OF
COMPUTATIONAL MECHANICS TOWARDS IMPROVED UNDERSTANDING OF THE BIOMECHANICS OF

... 5. Engineering Properties ........................................................................................................ 27 ...
Three-dimensional alignment of the aggregated myocytes in the
Three-dimensional alignment of the aggregated myocytes in the

... the level of slice 4. For illustration purposes, the shown slices represent the center of the actual diffusion scans that had a slice thickness of 1 mm but no interslice gaps. The assessment of helical angles (B) and intruding angles (C) is illustrated with the help of a representative chain of myoc ...
Increase of QRS Duration as a Predictor of Impending Ventricular
Increase of QRS Duration as a Predictor of Impending Ventricular

... myocardial infarction model, previously reported in [14]. The first phase, named Ia phase, occurs from 2 to 10 minutes after the onset of ischemia, whereas the second phase, or Ib phase, appears after an arrhythmia-free interval, between 12 and 30 minutes. Since Ia and Ib phases suggest different me ...
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Heart failure



Heart failure (HF), often referred to as congestive heart failure (CHF), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs. The terms chronic heart failure (CHF) or congestive cardiac failure (CCF) are often used interchangeably with congestive heart failure. Signs and symptoms commonly include shortness of breath, excessive tiredness, and leg swelling. The shortness of breath is usually worse with exercise, while lying down, and may wake the person at night. A limited ability to exercise is also a common feature.Common causes of heart failure include coronary artery disease including a previous myocardial infarction (heart attack), high blood pressure, atrial fibrillation, valvular heart disease, excess alcohol use, infection, and cardiomyopathy of an unknown cause. These cause heart failure by changing either the structure or the functioning of the heart. There are two main types of heart failure: heart failure due to left ventricular dysfunction and heart failure with normal ejection fraction depending on if the ability of the left ventricle to contract is affected, or the heart's ability to relax. The severity of disease is usually graded by the degree of problems with exercise. Heart failure is not the same as myocardial infarction (in which part of the heart muscle dies) or cardiac arrest (in which blood flow stops altogether). Other diseases that may have symptoms similar to heart failure include obesity, kidney failure, liver problems, anemia and thyroid disease.The condition is diagnosed based on the history of the symptoms and a physical examination with confirmation by echocardiography. Blood tests, electrocardiography, and chest radiography may be useful to determine the underlying cause. Treatment depends on the severity and cause of the disease. In people with chronic stable mild heart failure, treatment commonly consists of lifestyle modifications such as stopping smoking, physical exercise, and dietary changes, as well as medications. In those with heart failure due to left ventricular dysfunction, angiotensin converting enzyme inhibitors or angiotensin receptor blockers along with beta blockers are recommended. For those with severe disease, aldosterone antagonists, or hydralazine plus a nitrate may be used. Diuretics are useful for preventing fluid retention. Sometimes, depending on the cause, an implanted device such as a pacemaker or an implantable cardiac defibrillator may be recommended. In some moderate or severe cases cardiac resynchronization therapy (CRT) may be suggested or cardiac contractility modulation may be of benefit. A ventricular assist device or occasionally a heart transplant may be recommended in those with severe disease despite all other measures.Heart failure is a common, costly, and potentially fatal condition. In developed countries, around 2% of adults have heart failure and in those over the age of 65, this increases to 6–10%. In the year after diagnosis the risk of death is about 35% after which it decreases to below 10% each year. This is similar to the risks with a number of types of cancer. In the United Kingdom the disease is the reason for 5% of emergency hospital admissions. Heart failure has been known since ancient times with the Ebers papyrus commenting on it around 1550 BCE.
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