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InsP 3 R domains - Yale School of Medicine
InsP 3 R domains - Yale School of Medicine

Presentation (PowerPoint File) - IPAM
Presentation (PowerPoint File) - IPAM

... – e.g. adenylyl cyclase – converts ATP to cAMP depending on regulation at the effector enzyme – this pathway can be either activated or inhibited – by the type of G protein activated by the hormone-receptor complex – Gs proteins result in stimulation of the effector enzyme – Gi proteins result in in ...
Cellular Respiration and Combustion
Cellular Respiration and Combustion

... sugars into ATP WITHOUT oxygen.  Fermentation is also called anaerobic cellular respiration  C6H12O6 → CO2 + C2H6O + 2ATP  Balance the equation now. ...
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... electron pairs to the electron transport chain, ultimately fueling ATP production by the F1F0 ATP synthase. If oxygen is limited, some GTP (essentially equivalent to ATP) can still be generated by the Krebs cycle step in which succinyl CoA is converted to succinate. Note that making the glutamine in ...
Title New tricks for KDEL receptors Author(s)
Title New tricks for KDEL receptors Author(s)

... DENV4, one of the four serotypes, and West Nile virus, a member of the same Flaviviridae family, was not affected by KDELR depletion, suggesting that there might be some alternatives to KDELR-assisted transportation, an area that we are actively investigating. These findings identify KDELR as the fi ...
Lecture 17 and 18: Cellular Signaling Reference: Lieberman and
Lecture 17 and 18: Cellular Signaling Reference: Lieberman and

...  Endocrine: source of hormone and target of hormone far apart.  Paracrine: source of hormone and target of hormone adjacent.  Autocrine: cell produces and receives its own signals. 6. List the 5 basic types of receptor and list the three types of plasma membrane receptor.  Types of receptors o L ...
The Point is to Make ATP! Making energy!
The Point is to Make ATP! Making energy!

G-protein-mediated pathway
G-protein-mediated pathway

... (1) Type I and type II receptors for TGF(beta) in a cell prior to binding of the growth factor. (2) Binding of growth factor results in clustering of type I and type II receptors, and phosphorylation of type I receptors by type II ...
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... • Transcription factor—activate or inhibit • Steroidal anti-inflammatory ...
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BPS 502

... -Ras proteins contain a covalently linked lipid group that anchors the protein to the cytoplasmic face of the plasma membrane -There are multiple Ras proteins, each acting in distinct cell types -Ras functions as a switch, cycling between 2 conformational states -mutations of the ras gene promote th ...
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Protein Folding?

... • Luminescent bacteria tags – Insert luciferase gene into symbiotic bacteria that can live in certain organisms ...
An Introduction to Neurophysiology
An Introduction to Neurophysiology

... A. Types of Synapses 1. Electrical Synapses - gap junctions → direct electrical connection between cells - uncommon in the nervous system 2. Chemical Synapses - most common type in the nervous system - release a chemical neurotransmitter which binds to a receptor presynaptic cell (neuron) axon termi ...
Microsoft PowerPoint
Microsoft PowerPoint

... Chapter 9 – Energy in a Cell All living organisms must be able to obtain energy from their environment 1. Most cell functions require __________. 2. Examples: a) Making ______________ or synthesizing other macromolecules b) Essential for maintaining ________________ by moving molecules through the m ...
BIO 212 SI Kukday-- Nervous System (2) 4/11
BIO 212 SI Kukday-- Nervous System (2) 4/11

... 1060 Hixson-Lied Student Success Center  515-294-6624  sistaff@iastate.edu  http://www.si.iastate.edu ...
Endothelial Barrier Function Adenosine
Endothelial Barrier Function Adenosine

... During episodes of inflammation, multiple cell types release adenine nucleotides in the form of ATP, ADP, 5ⴕ-AMP, and adenosine. In particular, following activation, polymorphonuclear leukocytes release larger quantities of 5ⴕ-AMP. Extracellular 5ⴕ-AMP is metabolized to adenosine by surface-expresse ...
expression and function of receptors for leptin and ghrelin in sh
expression and function of receptors for leptin and ghrelin in sh

... pathways. 3) Exposure for 3-6 h to 10-12 M/10-8 M leptin led to a reduction of NPY mRNA levels, with a maximal efficacy at the lowest concentrations tested. Leptin treatment for a short time (5-60 min) was associated with a significant increase of NPY release, probably due to membrane depolarization ...
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Gene Section EPHA3 (EPH receptor A3) Atlas of Genetics and Cytogenetics

Harvard-MIT Division of Health Sciences and Technology HST.131: Introduction to Neuroscience
Harvard-MIT Division of Health Sciences and Technology HST.131: Introduction to Neuroscience

... • The opposite of LTP • Long lasting reduction in synaptic sensitivity • Removal of AMPARs ...
G protein–coupled receptors
G protein–coupled receptors

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G-protein linked receptor

... Human body consists of trillions of cells, 200+ specialized cell types that must differentiate (next time) and communicate (today) with one another ...
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'Receptor-ligand interactions - cell signaling, adhesion

RAS (overview) Midwest 2013
RAS (overview) Midwest 2013

... The Ras mitogen-activated protein kinase (MAPK) cascade, including Raf, Mek and Erk, is a ubiquitous signaling module that couples receptor-mediated events at the cell surface to cytoplasmic and nuclear effectors. The Ras MAPK cascade is perhaps best known for its crucial role in mediating the trans ...
Dependence of an Adenosine-Activated Potassium Current on a
Dependence of an Adenosine-Activated Potassium Current on a

CASE 1
CASE 1

... able to pass through the cell membrane, often in a regulated manner. The current understanding is that the cell membrane consists mainly of a bilayer of phospholipids positioned so that their hydrophilic components face the aqueous intracellular and extracellular fluids and their hydrophobic portion ...
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Purinergic signalling



Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.
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