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Pathophysiology of Heart failure
Pathophysiology of Heart failure

... a) oxygen deprivation (e.g. coronary heart disease) b) inflammation (e.g. increased metabolic demands) ...
first heart sound - Easymed.club
first heart sound - Easymed.club

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... complications can occur that lead to the death of the patient. For this reason the exact diagnosis and monitoring of the progression in a timely manner is of critical clinical interest in order to be able to predict the risk of decompensation, determine a prognosis and adopt an appropriate medical p ...
Basic Physiology and Approach to Heart
Basic Physiology and Approach to Heart

... No heart sounds should occur during this phase as the opening of the valves upon ejection of the blood is silent. If there is a sound then this may indicate a sign of valve disease or intracardiac shunts. ...
AJS_Paper3_Autoimmunity
AJS_Paper3_Autoimmunity

... lifelong consequences. By an unknown mechanism, the immune system kills the insulinproducing beta cells in the pancreas. Insulin is the hormone that enables the body to absorb glucose from the bloodstream. People who suffer from T1D must closely monitor their blood-glucose levels and ensure they are ...
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PATHOPHYSIOLOGY OF HEART FAILURE
PATHOPHYSIOLOGY OF HEART FAILURE

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Heart sounds Lecture (2012).
Heart sounds Lecture (2012).

...  2nd component occurs due to the closure of the A-V valves  3rd component is produced when semi-lunar valves open  4th component produced due to turbulent blood flow into large arteries  The mitral component heard at the apex beat area [left 5th intercostal ...
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Ideal Ventricular Assist Device
Ideal Ventricular Assist Device

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Cardiomyopathies
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Resting heart rate and cardiovascular events: time for a new crusade?
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... duration (some patients die after the first plaque rupture) and its symptomatology (some ruptures remain silent): this is the ‘vulnerable’ period. Risk factors for plaque rupture are summarized in Figure 1, but, to date, remain only incompletely identified. It is not known whether some risk factors ...
Cardiac glycosides, antiarrhymic and antianginal drugs
Cardiac glycosides, antiarrhymic and antianginal drugs

... therapy of heart failure • Phosphodiesterase inhibitors are used for short-term control of acute/advanced heart failure that is unresponsive to the “more conventional” ( i.e. diuretics and ACE inhibitors) treatments. ...
Autoimmunity - Lehigh University
Autoimmunity - Lehigh University

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Atrial Fibrillation Information Sheet
Atrial Fibrillation Information Sheet

... may cause chest pain, shortness of breath, dizziness, weakness or fatigue. In some patients there are no accompanying symptoms. ...
PowerPoint - Delmar
PowerPoint - Delmar

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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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