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Post streptococcal glomerulonephritis (PSGN)
Post streptococcal glomerulonephritis (PSGN)

... Two “nephritogenic” proteins have thus far been identified in Streptococcal infections and include SpeB, a bacterial serine protease enzyme, and NAPIr, a secreted bacterial protein known as “nephritis-associated plasmin receptor”. It is thought that these proteins when present in the kidney precipita ...
Medical and Surgical Asepsis - Faculty Sites
Medical and Surgical Asepsis - Faculty Sites

... leading to destruction of antigens and creation of antibodies that subsequently protect from the same antigen ◦ Five classes of antibodies  IgG, IgM, IgA, IgE, and IgD. IgG is most abundant and crosses the placenta provides passive immunity for newborns. ...
Lab 6: Cardiac EKG lab
Lab 6: Cardiac EKG lab

... blood to the arteries (either the pulmonary arteries or the aorta). One cardiac cycle is completed when the heart fills with blood and the blood is pumped out of the heart. The cycle of contraction and relaxation of the heart can be determined by auscultation or the use of a stethoscope to listen fo ...
Mitral/Tricuspid Regurgitation Due to Myxomatous Heart
Mitral/Tricuspid Regurgitation Due to Myxomatous Heart

... moves through correctly and into the circulation. This heart valve disorder has many names: “endocardiosis,” “degenerative valvular disease,” and “myxomatous valve degeneration” are some of the more common synonyms. The different names refer to the same process: an abnormal thickening and distortion ...
Congenital heart diseases is a category of heart disease that
Congenital heart diseases is a category of heart disease that

... In more severe cases, these problems may develop shortly after birth. However, symptoms sometimes don't develop until the teenage years or early adulthood. ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

... are delayed by one or more days (delayed type hypersensitivity).  Delay ...
Allergy
Allergy

... skin, but antibodies contribute to the rejection of certain transplants, especially bone marrow. In experimental animals, rejection of most types of grafts can be transferred by cells, not serum. Also, T celldeficient animals do not reject grafts but B cell-deficient animals do. If a second allograf ...
Heart Failure Fact Sheet - Barth Syndrome Foundation
Heart Failure Fact Sheet - Barth Syndrome Foundation

... everyone. Heart failure is a chronic condition characterized by the heart's diminished ability to pump blood effectively. Children with Barth syndrome are at an increased risk of developing heart failure. Small areas of damage may occur over years, damaged muscle tissue is replaced by scar tissue. T ...
Document
Document

... • The shorter the PR interval, the louder the first heart sound (mitral valve leaflets are wide open and deep within the ventricle when contraction begins causing the leaflets to close forcefully. • The longer the PR interval, the softer the first sound • The PR interval directly influences the posi ...
Ventricular and Atrial Septal Defects
Ventricular and Atrial Septal Defects

... Small ASDs and VSDs usually are not corrected, because they do not commonly shorten an animal’s life span. If the ASD or VSD is large and has resulted in heart failure, the heart failure is treated with diuretics (furosemide), vasodilators (enalapril), and an agent that improves heart contractions ( ...
ARVD Program Brochure
ARVD Program Brochure

... should discuss appropriate guidelines for diet and healthy living, as well as symptoms that could indicate a complication related to the disease, medications, or other treatments. ...
Immunology Phagocytes Killer T-cells Macrophages
Immunology Phagocytes Killer T-cells Macrophages

... Applications of Immune Response Immunization= process that increases an organism’s rxn to antigen & therefore improves its ability to resist or ...
Sign & Symptom - سایت دانشگاه علوم پزشکی گیلان
Sign & Symptom - سایت دانشگاه علوم پزشکی گیلان

... Trismus , Laryngeal edema Fever , Pain , Dysphagia ,……. Treatment: Penicillin (cr.) I.V. Surgery if infectious collection (You have to think about airway & tracheotomy ) ...
Fever and Relative Bradycardia: A Case
Fever and Relative Bradycardia: A Case

... temperature relationship [8]. This pulse-temperature deficit is also known as Faget’s sign and is attributed to a 19th century physician by the name of Jean-Charles Faget [9]. He was analyzing yellow fever in New Orleans in the 1860s, when he noted that there was a consistent relationship between a ...
Arrhythmia - British Heart Foundation
Arrhythmia - British Heart Foundation

... normally happens because of a heart block. This is where the electrical message from the top to the bottom of your heart gets delayed or doesn’t get through. This can be due to problems in the SA node and the AV node. They are the tissue areas between the atria and the ventricles of your heart. Some ...
Infectious disease
Infectious disease

... the invader for next time so it will be quickly destroyed. ...
CRP (C-Reactive Protein)
CRP (C-Reactive Protein)

... • Its plasma concentration increases during inflammatory states • CRP is a pattern recognition molecule, binding to specific molecular configurations that are typically exposed during cell death or found on the surfaces of pathogens. • Its rapid increase in synthesis within hours after tissue injury ...
Heart and Circulatory System?Arrhythmia (Irregular Heartbeat)
Heart and Circulatory System?Arrhythmia (Irregular Heartbeat)

... during waking hours raises the risk of incapacitation to an unacceptable level, and the FAA will most likely deny certification. A resting heart rate of more than 100 beats per minute (rapid ventricular response) or episodes of heart rate greater than 130­140 with minimal exertion will also preclude ...
Scrappy Heart Mug Rug
Scrappy Heart Mug Rug

... Iron Fusible web to the back side of the 4 inch square of red fabric. Using the Go! Heart Die #55029 (or Template A on the last page) cut one medium 3 inch heart shape from this fabric. Refer to the picture and fuse the red heart to the pieced top just right of center, and with the top of the red he ...
Palpitations - COR Medical Group
Palpitations - COR Medical Group

... Palpitations can be due to an arrhythmia, usually due to a abnormally rapid heart rate. When the pulse or heart rate is over 100 beats per minute, it is called tachycardia. One can have sinus tachycardia where the heart rate increases in a normal way due to signals from the body. When it is due to t ...
AHA News Release Masthead
AHA News Release Masthead

... Sudden cardiac arrest is most often caused by an irregular heart rhythm called ventricular fibrillation. This irregular rhythm causes the heart’s electrical impulses to become chaotic, causing the victim to collapse and stop breathing normally. Unless a normal heart rhythm is restored, death will fo ...
No 77 : Heart failure-underlying causes and medication management
No 77 : Heart failure-underlying causes and medication management

... The severity of heart failure was defined using the New York Heart Association Classification. There were 4 classes, Class I (least severe) to Class IV (most severe). Class I heart failure was diagnosed in 2.1% of general practice patients, while 2.7%, 0.9% and 0.2% were diagnosed with Class II, III ...
7 Abstract from Mari..
7 Abstract from Mari..

... expression and shedding of the heparan sulfate (HS) proteoglycan syndecan-4 is upregulated in response to immune activation in failing hearts, and that the shed HS-substituted ectodomains mediate inflammatory events. Which enzymes regulate the shedding process and modulation of shed ectodomains, rem ...
presentation source
presentation source

... cells, they produce action potentials with a long plateau phase because of the slow, inward diffusion of Ca2+. E. The long action potential and long refractory period of myocardial cells allows the entire mass of cells to be in a refractory period while it contracts. This prevents the myocardium fro ...
click here  - Cardiomyopathy UK
click here - Cardiomyopathy UK

... Current prevalence figures suggest that at least 1 in every 500 of the population has cardiomyopathy, although many are asymptomatic and go undiagnosed. Patients with cardiomyopathy may present with a range of symptoms, or with a relevant family history pointing towards a genetic causation (see over ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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