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T lymphocyte
T lymphocyte

... Institute of Immunology, ZJU ...
The Human Immune System
The Human Immune System

... - Phagocytes – eat invaders - T-cells – kill invaders ...
Chapter 29: Immunology - Laboratory Animal Boards Study Group
Chapter 29: Immunology - Laboratory Animal Boards Study Group

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Chapter 18 Defense Mechanisms of the Body
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... • Transfusion reactions are the illness caused when erythrocytes are destroyed during blood transfusion. • It is caused by antibodies rather than cytotoxic T cells. • Erythrocytes do not have MHC proteins, but they do have plasma membrane proteins and carbohydrates that can function as antigens. • T ...
341-541 - McDermott.doc
341-541 - McDermott.doc

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... 1 Oryong-dong, Puk-ku, Gwangju 500-712 Korea Attacking of self-components by auto-reactive T cells and/or B cells causes a damage or loss of organ function resulting in diverse immune disorders. Autonomic neuropathies often caused by specific anti-self antibodies such as anti-nuclearantibodies, neur ...
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Immune System Basics - Wayzata Public Schools

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Thymus



The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, T cells or T lymphocytes mature. T cells are critical to the adaptive immune system, where the body adapts specifically to foreign invaders. The thymus is composed of two identical lobes and is located anatomically in the anterior superior mediastinum, in front of the heart and behind the sternum. Histologically, each lobe of the thymus can be divided into a central medulla and a peripheral cortex which is surrounded by an outer capsule. The cortex and medulla play different roles in the development of T-cells. Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow resident hematopoietic stem cells). Developing T-cells are referred to as thymocytes and are of hematopoietic origin. Stromal cells include epithelial cells of the thymic cortex and medulla, and dendritic cells.The thymus provides an inductive environment for development of T cells from hematopoietic progenitor cells. In addition, thymic stromal cells allow for the selection of a functional and self-tolerant T cell repertoire. Therefore, one of the most important roles of the thymus is the induction of central tolerance.The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to atrophy and thymic stroma is mostly replaced by adipose (fat) tissue. Nevertheless, residual T lymphopoiesis continues throughout adult life.
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