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The Immune System
The Immune System

... Books. Sonny Julius, 25 Jan. 2009. Web. 30 Dec. 2012. . Shomon, Mary J. . "How Does the Immune System Work? ." Thyroid Disease Information - Hypothyroidism Hyperthyroidism - Thyroid Cancer - Autoi ...
NVCC Bio 212
NVCC Bio 212

... small in an adult - decreases in size after puberty ...
Safe Immunoguard Leaf Leaf .pmd - sbpl
Safe Immunoguard Leaf Leaf .pmd - sbpl

... The ability of birds to fight against infections and disease is determined by its capability to invade pathogens. The body protects itself against foreign materials such as virus and bacteria through its immune system. Immune system triggers the action of lymphocytes i.e white blood cells (WBC) or m ...
Immune System Reading and Questions
Immune System Reading and Questions

... There are nutritional things a person can do to help strengthen his/her immune system. Vitamins A, C, and E area collectively known as the anticancer vitamins. The immune system needs these plus minerals like zinc (Zn) and selenium (Se) to do its job. Dark green leafy vegetables, especially cabbage ...
Cells of the Immune System-I
Cells of the Immune System-I

... activation requires “Two Signals” (from Antigen presenting cells (APCs)) ...
Slide 1
Slide 1

... • Made by B-cell lymphocytes • 1011 B-cells in body, each with specific antibody, present for life • Each B-cell has 100,000’s of copies of its antibody embedded in cell membrane, called B-Cell Receptors (BCR) • When a BCR reacts or gloms onto an antigen that it recognizes, that cell is stimulated t ...
development of autoimmunity
development of autoimmunity

... ROLE OF INFECTIONS IN THE DEVELOPMENT OF AUTOIMMUNITY MOLECULAR MIMICRY MAY LEAD TO SEVERE AUTOIMMUNE REACTIONS ...
FIB KC Lymphocytes-Immunity
FIB KC Lymphocytes-Immunity

... ◦ Each B-lymphocyte is pre-programmed to produce only ______ specific ____________ against one specific ________________. ◦ Cell surface has thousands of ________________ against that specific antigen. ◦ Each antigen has a unique shape on it’s surface called an _______________. ◦ When antigen binds ...
FIB KC Lymphocytes-Immunity
FIB KC Lymphocytes-Immunity

... ◦ Each B-lymphocyte is pre-programmed to produce only ______ specific ____________ against one specific ________________. ◦ Cell surface has thousands of ________________ against that specific antigen. ◦ Each antigen has a unique shape on it’s surface called an _______________. ◦ When antigen binds ...
T CELL DEFICIENCY - immunology.unideb.hu
T CELL DEFICIENCY - immunology.unideb.hu

... • Neither T cell-dependent antibody response nor cellular immunity are functional • T-, B+ NK- SCID • T- B- NK+ ...
17_18 pathology-deficiency_short
17_18 pathology-deficiency_short

... • Neither T cell-dependent antibody response nor cellular immunity are functional • T-, B+ NK- SCID • T- B- NK+ ...
Lymphatic System and Immunity
Lymphatic System and Immunity

...  Antigens: A chemical that stimulates B lymphocytes to produce antibodies  Lymphocytes: A type of white blood cell that provides ...
30.6 Lymphatic System KEY CONCEPT The lymphatic system provides another type of
30.6 Lymphatic System KEY CONCEPT The lymphatic system provides another type of

... • Structures in the lymphatic system help fight disease. – tonsils filter bacteria and viruses – thymus develops white blood cells – spleen filters lymph, contains immune cells ...
Biol 155 Human Physiology
Biol 155 Human Physiology

... Humoral or Antibody-mediated: B cells Cell-mediated: T cells ...
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Major functions of the immune system

... T cell and B cell Formation B cells are coated with immunoglobulins : give them the ability to recognize that foreign proteins and stimulate an antigen-antibody reaction. The immunoglobulins are usually all present during an immune response, but in varying amounts depending on the specific antigen ...
3.Lecture 5- Resistance of the Body to infection
3.Lecture 5- Resistance of the Body to infection

... • High mol. weight (>8000) • Antigenicity due to presence of characteristic epitopes (molecular groups) on its surface ...
Immunology – Immune System Overview
Immunology – Immune System Overview

... The immune system is the body’s only protective system, and comprises of various mechanisms whereby non-body particles are killed off or prevented from entering the body’s normal metabolism. There are a number of different pathogenic organisms which cause disease and thus disturb the body’s normal f ...
Autoimmunity in primary immune deficiency: taking lessons from our
Autoimmunity in primary immune deficiency: taking lessons from our

... almost devoid of autoimmune diseases, B cells which are present, but dysfunctional in other defects, lead to a significant incidence of autoimmune disease. Autoimmunity is also particularly common in the antibody deficiency states. Although organ-based autoimmunity also occurs, for unclear reasons t ...
IDF PRESEnTS - Immune Deficiency Foundation
IDF PRESEnTS - Immune Deficiency Foundation

... the planet. Not all bacteria can cause problems, but some are pathogenic bacteria that cause disease. When the body’s skin or mucous membranes are broken due to disease, inflammation, or injury, bacteria can enter the body. Your immune system usually limits the impact bacteria can have on your healt ...
Chapter Fourteen Lymphatic and Immune Systems
Chapter Fourteen Lymphatic and Immune Systems

... organs composed of lymph tissue Thymus gland ...
Slides - SENS Research Foundation
Slides - SENS Research Foundation

... • Major complication of BMT • Caused by donor T lymphocytes that see recipient antigens as “non-self” • Disease of skin, liver, intestines • Prevented by marrow T cell depletion, but this increases relapse rates, because donor T cells also eradicate leukemia cells ...
What is an Autoimmune Disease?
What is an Autoimmune Disease?

... Many B cells mature into what are called plasma cells that produce antibodies (proteins) necessary to fight off infections while other B cells mature into memory B cells. B cells work in co-ordination as whilst one set may produce antigens in order to fight off infection or bacteria whilst the other ...
Lymphatic System - Dr. Annette M. Parrott
Lymphatic System - Dr. Annette M. Parrott

... Lymph Nodes Spleen Thymus Tonsils Peyer’s patches MALT ...
Immune Compromised Infections
Immune Compromised Infections

... intracellular killing and chemotactic movement accompanied by inability of phagosome and lysosome fusion and proteinase deficiency. Respiratory burst is normal. Associated with NK cell defect, platelet and ...
chapter 19 autoimmunity: breakdown of self-tolerance
chapter 19 autoimmunity: breakdown of self-tolerance

... HASHIMOTO'S THYROIDITIS. Autoimmune damage to the thyroid, primarily by the humoral response, results in decreased function and clinical hypothyroidism. It is characterized by the presence of circulating antibodies to thyroglobulin and thyroid peroxidase as well as to microsomal proteins and other c ...
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Thymus



The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, T cells or T lymphocytes mature. T cells are critical to the adaptive immune system, where the body adapts specifically to foreign invaders. The thymus is composed of two identical lobes and is located anatomically in the anterior superior mediastinum, in front of the heart and behind the sternum. Histologically, each lobe of the thymus can be divided into a central medulla and a peripheral cortex which is surrounded by an outer capsule. The cortex and medulla play different roles in the development of T-cells. Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow resident hematopoietic stem cells). Developing T-cells are referred to as thymocytes and are of hematopoietic origin. Stromal cells include epithelial cells of the thymic cortex and medulla, and dendritic cells.The thymus provides an inductive environment for development of T cells from hematopoietic progenitor cells. In addition, thymic stromal cells allow for the selection of a functional and self-tolerant T cell repertoire. Therefore, one of the most important roles of the thymus is the induction of central tolerance.The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to atrophy and thymic stroma is mostly replaced by adipose (fat) tissue. Nevertheless, residual T lymphopoiesis continues throughout adult life.
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