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CANCER = UNCONTROLLED CELL DIVISION
CANCER = UNCONTROLLED CELL DIVISION

... Cancers are thought to start when changes occur in the genes that control cell division. Mutated gene that causes cancer is an oncogene, a change in any gene called mutation. Mutations are not unusual events, and most mutated cells are either crippled in some way that results in their early death or ...
35-2 Defense Against Infection Worksheet
35-2 Defense Against Infection Worksheet

... 16. Humoral immunity is a response to pathogens in blood and lymph. 17. The first response of humoral immunity to infection is much faster than the second response. 18. Plasma cells are specialized B cells. 19. Cell-mediated immunity involves antibodies. 20. Cell-mediated immunity causes infected bo ...
TARGET: TUMOR MICROENVIRONMENT Study led by Ludwig
TARGET: TUMOR MICROENVIRONMENT Study led by Ludwig

Circulatory System 1
Circulatory System 1

... in your body • Contain hemoglobin, which clings to oxygen molecules • Red blood cells are why blood looks red ...
Ch 12 Adaptive Defense Mechanisms
Ch 12 Adaptive Defense Mechanisms

... to a receptor on a specific B cell (B cells with non-complementary receptors remain inactive) ...
Immunity and Microbes
Immunity and Microbes

... Macrophages-very important cell of the immune system. An antigen presenting cell (APC), phagocytic cell, and recruiting cell in the inflammatory response Neutrophils- phagocytic cell that is often the first line of ...
1. What proteins attach to antigens on bacteria or free viruses
1. What proteins attach to antigens on bacteria or free viruses

... 1. What proteins attach to antigens on bacteria or free viruses, marking them for destruction by phagocytes or complement? a) T cells b) antibodies c) B cells d) APC 2. What system carries immunity  producing antibodies through the body? a) circulatory system b) skeletal system c) excretory system ...
LN #13 Immune
LN #13 Immune

... Specialized to attack infected body cells and cancer cells Recognizes infected cells by the antigens on its surface. Once a cells is recognized as infected it is quickly killed. ...
Innate vs. Adaptive Immunity - Welcome to people.pharmacy.purdue
Innate vs. Adaptive Immunity - Welcome to people.pharmacy.purdue

... • Identified by numbers • Used to classify leukocytes into functionally distinct subpopulations, e.g. helper T cells are CD4+CD8-, CTLs are CD8+CD4• Often involved in leukocyte functions Antibodies against various CD molecules are used to: • Identify and isolate leukocyte subpopulations • Study func ...
Computational Immunology An Introduction
Computational Immunology An Introduction

... which surround nerve cells • T cells erroneously attack the Myelin Basic Protein (MBP) on the surface of the Myelin cells • Well-studied protein; known which regions are immunogenic ...
5.3 KeyTerms
5.3 KeyTerms

Cellular organisation
Cellular organisation

The Immune System
The Immune System

Snímek 1
Snímek 1

... Genes assiciated with antigen clearance (complement proteins) Genes associated with tolerance induction (CTLA-4, Fas-FasL) ...
Chapter 35- Infectious Diseases
Chapter 35- Infectious Diseases

... • Interferons- when viruses infect organism, certain cells produce protein that interferes with the viruses production of protein for reproduction. • This slows down how quickly viruses can reproduce and allows the body to start SPECIFIC DEFENSES. ...
Studying the Effects of Congaplex® and
Studying the Effects of Congaplex® and

... provoke an immune response (antigen). The researchers then measured immune activity via the production of cytokines, proteins that regulate the action of the immune system. These chemicals are released by T cells and have a variety of different tasks. Some, like tumor necrosis factor alpha and inter ...
The Cell: A Review
The Cell: A Review

... Through mitosis, cells replicate their DNA and then pass these complete sets of genetic material to their offspring, the daughter cells created when they divide. The fluid-filled region between the nucleus and the cell membrane is called the cytoplasm. For many years scientists thought that very lit ...
The Body`s Lines of Defense
The Body`s Lines of Defense

...  (a) Patient X. Indicators are reduced red and white blood cell counts.  (b) Patient Z. Indicators are higher body temperature and an elevated white blood cell count. The red blood cell count is normal.  (c) Patient Y. Indicators are increased white blood cell count and reduced red blood cell c ...
antigen
antigen

... exposed to the pathogen, the memory cells recognize it and divide rapidly – producing many more antibodies. This eliminates the invader before it can cause illness. ...
pptx - BSMMU
pptx - BSMMU

... introduction of genes that encode proteins that recognize antigens expressed by target tumor cells. 2. Chimeric Antigen Receptor (CAR) T cells: Here genes can encode chimeric tumor antigen-specific receptors, or T bodies, that target surface antigens in an MHCindependent fashion. ...
INF107
INF107

Typical violations of immunobiological supervision 1. The main
Typical violations of immunobiological supervision 1. The main

... 6. Autoimmune diseases can be caused by: + a) disorders of the immune system, manifested in the appearance of antibodies to antigens of own normal cells; + b) protein denaturation of own cells and tissues; + c) formation of antibodies to proteins of cells and organs that are isolated in the ontogeny ...
Prospective analysis of dendritic cell (DC) therapy in cancer patients`.
Prospective analysis of dendritic cell (DC) therapy in cancer patients`.

... During cancer development, self-cells become non-self cells. Mutating cells acquire a shield mechanism for evading immune attack. They may hide their antigenic nature by topographic shield or produce IL-10 for negative chemotaxis or develop an unknown hidden mechanism to evade their arrest. Once the ...
Immunology
Immunology

... Fusion of vesicles (peptide fragments with MHC-II molecules) Binding of peptide fragments to MHC-II molecules Insertion of antigen-MHC-II complex into plasma membrane ...
Antibody production
Antibody production

... They secrete cytokines that activate macrophages and help B cells The activation of T cells requires: Recognition of peptide –MHC complex ...
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Adoptive cell transfer

Adoptive cell transfer (ACT) is the transfer of cells into a patient; as a form of cancer immunotherapy. The cells may have originated from the patient him- or herself and then been altered before being transferred back, or, they may have come from another individual. The cells are most commonly derived from the immune system, with the goal of transferring improved immune functionality and characteristics along with the cells back to the patient. Transferring autologous cells, or cells from the patient, minimizes graft-versus-host disease (GVHD) or what is more casually described as tissue or organ rejection.
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