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S. Typhi-specific CD8+ T EM responses
S. Typhi-specific CD8+ T EM responses

...  Uncovered, for the first time, that S. Typhi-specific CD8 T cell baseline responses correlate significantly with clinical outcome after infection  Revealed some of the immunological mechanisms responsible for delayed time to disease onset  Demonstrated that multifunctional T cells appear to play ...
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Immune Primer - Life Sciences Outreach Program
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... • Organelles found in a macrophage are nucleus, lysosomes, mitochondria, and ER • Releases substances to stimulate other cell in the immune system. • Removes cellular debris from the lungs. • Helps in muscle repair, growth, and regeneration. • Macrophages help in disease like Tuberculosis, Heart dis ...
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... Antibody-dependent cell-mediated cytotoxicity (ADCC) • Antigen specificity provided by antibody • Antibody functions as a bridge between effector cell and and the target antigen • Antibody Constant region Receptor (FcR) on NK cells recognizes Ab on “bad” cell – Release toxic chemicals to kill the ce ...
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... Two mutations of the RB locus on chromosome 13q14 lead to neoplastic proliferation of the retinal cells. In the familial form, all somatic cells inherit one mutant RB gene from a carrier parent. The second mutation affects the Rb locus in one of the retinal cells after birth. In the sporadic form, o ...
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... cell nucleus: (frumukjarni) The central and most important part of an object, movement, or group, forming the basis for its activity and growth stem cells: (stofnfrumur) An undifferentiated cell of a multicellular organism that is capable of giving rise to indefinitely more cells of the same type, a ...


... of antitumor activity, including decreases in the presence of tumor markers and tumor necrosis (reviewed in ref. 1). Other related approaches studied i.v. or intranasal administration of α-GalCer-pulsed APC fractions, generated from peripheral blood mononuclear cells (PBMC) using GM-CSF and IL-2, ei ...
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... cells of the immune system to kill tumour cells. However, they are also toxic and can give bad side effects such as septic shock (infection leading to serious low blood pressure). Another group of immune system therapy proteins currently used are antibodies. These proteins block the effect of one ty ...
System has Specificity and Memory
System has Specificity and Memory

... • Re-exposure to the same immunogen • Antibody synthesis, titer, and length of antibody persistence is rapid and amplified –Due to presence of memory cells ...
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Adoptive cell transfer

Adoptive cell transfer (ACT) is the transfer of cells into a patient; as a form of cancer immunotherapy. The cells may have originated from the patient him- or herself and then been altered before being transferred back, or, they may have come from another individual. The cells are most commonly derived from the immune system, with the goal of transferring improved immune functionality and characteristics along with the cells back to the patient. Transferring autologous cells, or cells from the patient, minimizes graft-versus-host disease (GVHD) or what is more casually described as tissue or organ rejection.
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