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Chapter 17 Genetics of Immunity
Chapter 17 Genetics of Immunity

... B. the heart and blood vessels and the blood cells within the vessels. C. about 2 trillion cells, their secretions, and the organs where they are produced and stored. D. all of the bacteria and viruses that are normally present in our bodies plus our blood cells. 2. An antigen is A. a molecule that ...
Chapter 17 Genetics of Immunity
Chapter 17 Genetics of Immunity

Presentation
Presentation

... the basis of distinct cytokine profiles and were called type 1 and type 2 helper cells (Th1 and Th2) • Many inflammatory diseases (mouse models first) thought to be caused by Th1 cells were not prevented by eliminating Th1 cells or their cytokines • Led to the discovery of the Th17 subset ...
chapter 13 t-cell/b-cell cooperation in humoral immunity
chapter 13 t-cell/b-cell cooperation in humoral immunity

... "runting" and poor general health, inability to make humoral responses to many (but not all) antigens, and lack of ability to reject skin grafts and carry out other cell-mediated immune reactions. They lack functional T-cells in the blood and peripheral lymphoid tissues. Implanting a fetal thymus (e ...
Mature T cells
Mature T cells

... Naive T cells that have recognized antigen without costimulation may become unresponsive to subsequent exposure to antigen, even if costimulations are present  anergy. Microbes, and cytokines produced during innate immune responses to microbes, induce the expression of costimulation, such as B7 mol ...
Week 2 Immunology
Week 2 Immunology

... A cluster of genes located in close proximity that determine histocompatibility antigens from members of a species. (eg. recognition of self versus non-self). ...
07 Cytokines
07 Cytokines

... Colony-Stimulating Factors (CSF) • Granulocyte-macrophage CSF (GM-CSF) promotes growth and differentiation of bone marrow progenitors • Macrophage CSF (M-CSF) is involved in development and function of monocytes and macrophages • Granulocyte CSF (G-CSF) stimulates production of polymorphonuclear leu ...
Biology Review - s3.amazonaws.com
Biology Review - s3.amazonaws.com

... • net transport of molecules from a region of higher concentration to one of lower concentration by random molecular motion. • net transport of molecules from a region of lower concentration to one of higher concentration by random molecular motion. • net transport of molecules from a region of high ...
NK Cells
NK Cells

Static
Static

... B cell response T cells also elicit a B cell response. B cells produce the antibodies: Anti-tissue transglutaminase (anti-tTG) Anti-deamidated gliadin Anti-endomysial antibody (anti-EMA) ...
SAONS Meeting
SAONS Meeting

... Lymphoid stem cells differentiate in to T and B cell lymphocytes. Multiple myeloma is a cancer of plasma cell or plasma B cells. Also known as plasma cell myeloma or Kahler’s disease. Plasma cells are the white blood cells that are responsible for the production of antibodies. Cancer of the B cells ...
Host Responses to Viral Infection - Cal State LA
Host Responses to Viral Infection - Cal State LA

... How do host cells fight back?  The TCR can only recognize and bind to its specific epitope if that epitope is associated with a self MHC (major histocompatability) molecule.  There are two basic types of MHC molecules  Class I MHC molecules are found on the surface of all nucleated cells.  Clas ...
The body`s response to infection File
The body`s response to infection File

... Antibody production occurs sooner (happens immediately – not really a big difference in graph), faster (Second exposure line is steeper) and more antibody is produced (peak is higher). ...
lymph nodes - Molecular Immunology
lymph nodes - Molecular Immunology

... *Are activated by T cell derived cytokines such as interferons: leading to increased phagocytosis and microbicidal activity (increased activity of degradative enzymes, nitrogen and oxygen free radical production and prostaglandins etc.). *Express receptors for Ab (FcR) and complement. *Act as scaven ...
Presentation - Online Veterinary Anatomy Museum
Presentation - Online Veterinary Anatomy Museum

... 1. Appreciate that the lymphoreticular system is divided into primary and secondary lymphoid organs. 2. Recognise that the structure of the BONE MARROW and THYMUS provides an ideal environment for B cell and T cell differentiation. 3. Describe how the structure of the LYMPH NODE is well adapted for ...
The immune system of the body produces specific antibodies to kill a
The immune system of the body produces specific antibodies to kill a

B cell - Catalyst
B cell - Catalyst

1. dia - Department of Immunology
1. dia - Department of Immunology

... Chemoattractant cytokines called chemokines direct migration of leukocytes to the appropriate anatomical sites ...
Lecture 4 Antigen Recognition
Lecture 4 Antigen Recognition

... antigen by special receptors. Antigen recognition depends on cellular cooperation. Cellular cooperation is controlled by recognition of MHC-encoded receptors. Antigen “drives” the process resulting in “effector” cells and “memory” cells. ...
Tan1
Tan1

... attack extracellular forms of pathogens. It was first discovered as an effector arm of the antibody response, but complement can also be activated early in infection in the absence of antibodies; complement first evolved as part of the innate immune system. Activation of complement involves the sequ ...
Some Basic Rules on how Cancer behaves
Some Basic Rules on how Cancer behaves

... 1 - Cancer loves and feeds on sugar – Cancer cells have up to 24X more glucose receptor sites than do normal healthy cells and they consume 10 -15X more glucose (sugar) than normal cells. Tumors of the central nervous system seem to be the most sensitive to glucose, but all cancerous growth is fed b ...
Immunicum provides Ad5PTDf35 adenovirus technology to Rutgers
Immunicum provides Ad5PTDf35 adenovirus technology to Rutgers

... About the Ad5PTDf35 adenovirus vector technology An adenovirus vector is a virus particle that can "infect" the DNA of cells with their own genetic material. The method is used in most of the gene therapies that are sold or are under development. The Ad5PTDf35 adenovirus vector was developed by a g ...
NK Cells
NK Cells

... • NK cells do not undergo rearrangement of receptor genes and, thus, do not express T cell receptors or CD3. • NK cell killing is not MHC restricted (identical killing levels are seen for allogeneic and syngenic tumor cells). • NK cells do not show immunologic memory that can be primed by re-exposur ...
Direct Cell Counting Assays for Immuno Therapy
Direct Cell Counting Assays for Immuno Therapy

... Celigo Benefits for Direct Cell Counting ADCC • Time-course tracking of % lysis can eliminate the need of multiple controls, and the effect of non-uniform cell seeding in the final cytotoxicity calculation. • Adherent cells can be measured and analyzed directly in the plate without trypsinization. • ...
IMMUNOLOGY SIMPLIFIED —from AIDS to ZZZZZZ
IMMUNOLOGY SIMPLIFIED —from AIDS to ZZZZZZ

... and are located on only on monocytes (in blood), macrophages (in tissues—APCs*), dendritic cells (in tissues just beneath the epithelial cells—APCs*), B lymphocytes (effector cells of the immune system) , activated T lymphocytes (effector cells of the immune system) • *Antigen processing cells—proce ...
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Adoptive cell transfer

Adoptive cell transfer (ACT) is the transfer of cells into a patient; as a form of cancer immunotherapy. The cells may have originated from the patient him- or herself and then been altered before being transferred back, or, they may have come from another individual. The cells are most commonly derived from the immune system, with the goal of transferring improved immune functionality and characteristics along with the cells back to the patient. Transferring autologous cells, or cells from the patient, minimizes graft-versus-host disease (GVHD) or what is more casually described as tissue or organ rejection.
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