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Second-Line Treatment of Non-Small Cell Lung Cancer: Clinical
Second-Line Treatment of Non-Small Cell Lung Cancer: Clinical

... Lung carcinoma is the leading cause of death by cancer in the world. Nowadays, most patients will experience disease progression during or after first-line chemotherapy demonstrating the need for new, effective second-line treatments. The only approved second-line therapies for patients without targ ...
Hydrocortisone - Queensland Ambulance Service
Hydrocortisone - Queensland Ambulance Service

... retrieval system or transmit in any form, or by any means, part or the whole of the Queensland Ambulance Service (‘QAS’) Clinical practice manual (‘CPM’) without the priorwritten permission of the Commissioner. The QAS accepts no responsibility for any modification, redistribution or use of the CPM ...
Invention reinvented
Invention reinvented

... to discover new medicines that go on to become standard treatments. The faltering economics of R&D productivity are jeopardizing that mission: R&D expenditure is not delivering. According to analysis, costs have ballooned to more than $1.6 billion per new drug approved, compared with $1 billion in 2 ...
CEDAC Final Recommendation and Reasons for
CEDAC Final Recommendation and Reasons for

... chemotherapy that is highly likely to cause nausea and vomiting. One study was of women treated with chemotherapy that is moderately likely to cause nausea and vomiting. • In all of the studies, patients were either given a placebo (a capsule that contained no active medicine) or they were given Eme ...
The Influence of an Interdisciplinary Diabetic Foot Team on the
The Influence of an Interdisciplinary Diabetic Foot Team on the

... compared to non-diabetics. They suggested that this decline might be due to an increased number of specialized diabetic foot disciplines. Although we did not find a change in amputation rates following the establishment of IDT, considering that patients managed by IDT had more severe lesions compare ...
Fasting and Medicines in Ramadhan
Fasting and Medicines in Ramadhan

... The results were quite alarming. It was found that 23% of patients did not take their medication at all during the holy month, and a further 48% doubled their evening dose to compensate for medicines normally taken twice a day. Doubling the dose of twice-daily medication or omitting a dose all toget ...
Diabetic Retinopathy and Diabetic Macular Edema
Diabetic Retinopathy and Diabetic Macular Edema

... panretinal laser photocoagulation resulted in a 50% reduction of severe visual loss.9 In the ETDRS, prompt laser was again associated with reduction in progression and visual loss even in less severe levels of retinopathy.10 It is thus important for the patient to receive prompt care. Fibrosis and s ...
Blank Jeopardy
Blank Jeopardy

Oncologic Emergencies: a Guide for Family Physicians
Oncologic Emergencies: a Guide for Family Physicians

... fibrinogen level.5 DIC: Do not delay definitive treatment (even if invasive), as DIC will not improve until the underlying cause is treated.13 In the meantime, coagulation and vital organ function must be supported.4,5,13 The need for large transfusions of platelets (a reasonable platelet target is ...
The Role of Endocrine System in the Inflammatory Process The
The Role of Endocrine System in the Inflammatory Process The

... in paracrine fashions. Therefore, exploring the mechanisms underlying the production and response to these mediators might broaden the horizons for the development of novel therapeutic options that target disease states in which the immune/inflammatory responses are compromised or dysregulated. This ...
INTRODUCTION TO SCIENTIFIC RESEARCH
INTRODUCTION TO SCIENTIFIC RESEARCH

Comparison of Enteropathic Spondyloarthritis and Ankylosing
Comparison of Enteropathic Spondyloarthritis and Ankylosing

... musculoskeletal symptoms to a rheumatologist first, a referral was made to our gastroenterology department to confirm or exclude IBD. This study was registered with our Research and Development Department and ethics approval was obtained from the local Ethics Committee. All patients were initially a ...
January - Neonatology Today
January - Neonatology Today

... vessels in the peripheral retina following Laser treatment, or the continued growth of vessels into the peripheral retina following Avastin treatment. While the preliminary results of this study are promising, without any early local or systemic complications, it has shown that IVB as monotherapy fo ...
Pseudomonas The chemokine CCL18 characterises infections in cystic fibrosis lung disease
Pseudomonas The chemokine CCL18 characterises infections in cystic fibrosis lung disease

... from CF patients compared with healthy controls. Within individual CF patients, CCL18 protein levels were consistently higher in serum than in sputum supernatants (fig. 1c). Despite these statistically significant differences between CF patients and healthy control subjects, the detected CCL18 prote ...
CONJUNCTIVA
CONJUNCTIVA

... Adenovirus (“pink eye”) occurs in epdemics • Highly contagious and can be transmitted through medical instruments cleaned with ...
SAQ revision notes
SAQ revision notes

...  A-a gradient more > x2 normal when CXR is normal and no other explanation  Compromised peripheral perfusion Request for CTPA / VQ scan should include  Well’s score  D-dimer level  Previous lung disease (asthma, COPD) for which patient required admission or under care of respiratory clinic Oeso ...
AARC Clinical Practice Guideline: Effectiveness of Pharmacologic
AARC Clinical Practice Guideline: Effectiveness of Pharmacologic

... The use of aerosolized agents to change sputum physical properties or improve airway clearance cannot be recommended for patients with NMD or weakness due to insufficient evidence. Postoperative Adult and Pediatric Patients Patients undergoing surgery are at risk for postoperative pulmonary complica ...
Clinical use of gadobutrol for contrast
Clinical use of gadobutrol for contrast

... agents, and their clinical use in CNS imaging is limited by the blood–brain barrier (BBB). There are negative CAs such as superparamagnetic particles/nanoparticles which primarily shorten T2 and T2* but none of these agents are commercially available for clinical applications for CNS imaging. With a ...
Evaluation of an Abnormal Urinalysis in the Asymptomatic Patient
Evaluation of an Abnormal Urinalysis in the Asymptomatic Patient

... when it is not permanent and when it occurs in association with other temporary physiological disturbances. Examples of this include albuminuria which occurs with fever, exacerbations of congestive heart failure, or severe exertion. Another kind of functional proteinuria is that which is detectable ...
Kidney News - August 2014 - American Society of Nephrology
Kidney News - August 2014 - American Society of Nephrology

... more than 2 kg and admitted to neonatal intensive care units, the incidence has been estimated in one study at 16 percent, and it may be much higher than that. Timothy Bunchman, MD, professor and director of pediatric nephrology at Virginia Commonwealth University School of Medicine in Richmond and ...
Canine Hyperadrenocorticism - VCA Specialty Animal Hospitals
Canine Hyperadrenocorticism - VCA Specialty Animal Hospitals

... being performed because of difficulties with glucose regulation. If you have a diabetic animal in which you suspect hyperadrenocorticism it is probably best to institute insulin therapy (even if it requires high doses) in order to regulate the diabetes. Once an adequate response to insulin therapy h ...
C52: Toxicology and Drug Testing in the Medical Laboratory, 3rd
C52: Toxicology and Drug Testing in the Medical Laboratory, 3rd

Kenalog-10® Injection - Bristol
Kenalog-10® Injection - Bristol

... Endophthalmitis, eye inflammation, increased intraocular pressure and visual disturbances including vision loss have been reported with intravitreal administration. Several instances of blindness have been reported following injection of corticosteroid suspensions into the nasal turbinates and intra ...
1: Gastro-intestinal system - Gateshead Health NHS Foundation Trust
1: Gastro-intestinal system - Gateshead Health NHS Foundation Trust

... increased risk of serious ventricular arrhythmia or sudden cardiac death. These risks may be higher in patients older than 60 years and in patients who receive daily oral doses of more than 30 mg. Non-prescription domperidone products are not recommended for use in patients with underlying cardiac d ...
Toxic Epidermal Necrolysis - Annals of International Medical and
Toxic Epidermal Necrolysis - Annals of International Medical and

... window period of 7 days from the date of exposure to index day is being considered. However it varies with half life of drugs for example it is 14 days for NSAIDS to 3 weeks for Phenobarbital.[3] Most common drug that leads to this disease is sulfonamides (cotrimoxazole). Antiepileptics like valproi ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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