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Characteristics of poisoning cases in Adiyaman city
Characteristics of poisoning cases in Adiyaman city

... Department of Anesthesiology and Reanimation, Faculty of Medicine, Adiyaman University Medical School, Adıyaman, Turkey ...
Retrospective Evaluation of Patients Diagnosed with Osteogenesis
Retrospective Evaluation of Patients Diagnosed with Osteogenesis

... clinic types according to Sillence classification; 13 cases (46.4%) was type 1, 10 cases (35.7%) type 3, and five cases (17.9%) type 4. Twenty four cases (85.7%) had repetitive fractures and four cases (14.3%) complained of bone deformities. Intrauterine fracture was identified in four cases. Only f ...
Annual Report - PhRMA Foundation
Annual Report - PhRMA Foundation

... scientists view toxicological effects of chemical substances, especially the dose–response relationship. It is now evident that many chemicals can induce subtle changes in cell signaling at doses well below those that cause an immediate or evident toxic response. Often, these changes represent an ad ...
Screening for a -Pi deficiency in patients with lung diseases M. Wencker
Screening for a -Pi deficiency in patients with lung diseases M. Wencker

... Patients with severe a1-Pi deficiency suffer from increased morbidity and mortality, which is mainly due to the development of chronic obstructive pulmonary disease (COPD) and pulmonary emphysema [1, 2]. The major known risk factors are active and passive smoking. Patients who stop smoking have a be ...
Allergy: An Overview
Allergy: An Overview

... This system accounts for the fact that multiple components of the immune system can be involved in various types of hypersensitivity reactions. For example, T cells play an important role in the pathophysiology of allergic reactions . In addition, the term immediate hypersensitivity is somewhat of a ...
Hepatic Encephalopathy: Diagnosis and Treatment
Hepatic Encephalopathy: Diagnosis and Treatment

... Hepatic Encephalopathy: Diagnosis and Treatment in urea cycle function for hyperammonemia to develop20; therefore, fasting ammonia concentrations are not sensitive for detection of hepatic parenchymal disease in the absence of multiple acquired PSSs.19 Some studies have noted that ammonia levels co ...
DeTeCTIng AnD DIAgnosIng BRAIn DIseAses WITH meDICAl ImAgIng
DeTeCTIng AnD DIAgnosIng BRAIn DIseAses WITH meDICAl ImAgIng

... images, which are superior to CT in the detection and characterisation of brain and spine diseases. MRI is the preferred imaging modality in children as it does not use radiation. Imaging protocols can be tailored to clinical questions and suspected diseases. Modern MRI techniques, now widely availa ...
E 2 A Clinical Safety Data Management: Definitions and
E 2 A Clinical Safety Data Management: Definitions and

... use (e.g., for an indication or population), should be reported or referenced to regulatory filings across other product presentations and uses. It is not uncommon that more than one dosage form, formulation, or delivery system (oral, IM, IV, topical, etc.) of the pharmacologically active compound(s ...
Common Gastrointestinal Problems
Common Gastrointestinal Problems

(PSD) November 2016 PBAC Meeting - (Word 228KB)
(PSD) November 2016 PBAC Meeting - (Word 228KB)

... one of which had to be a chemotherapy regimen. The ESC noted vorinostat may provide some patients with sufficient disease control to enable a stem cell transplant. The ESC also noted that vorinostat may reduce the size of the lesions and enable local treatments (eg radiotherapy) to be used. The PBAC ...
Guideline on Clinical follow-up gene therapy
Guideline on Clinical follow-up gene therapy

... screening, monitoring, diagnosis and treatment of diseases to detect injuries, complications, adverse reactions, medical errors, and indicators of declining medicinal product efficacy in humans after administration of a GT medicinal product. Clinical follow-up activities may be needed within days, w ...
The Faces of Personalized Medicine
The Faces of Personalized Medicine

... avoiding serious adverse events caused by the therapy, while other tests help to determine the optimal drug dose. Examples of these types of tests are found in a later section. Because of their ability to predict treatment outcomes, companion diagnostics are sometimes referred to as predictive bioma ...
Intensified Treatment for Tuberculous Meningitis in Adult
Intensified Treatment for Tuberculous Meningitis in Adult

... declined. However the morbidity and mortality overall are still high. HIV infection is associated with a worse outcome in TBM, the death rate at 9 months being 67% compared with 25% in HIV negative patients. The anti-tuberculous drugs have differing cerebrospinal fluid (CSF) penetration. In particul ...
Scleroderma lung disease - European Respiratory Review
Scleroderma lung disease - European Respiratory Review

... *Autoimmune Lung Center and Interstitial Lung Disease Program, National Jewish Health, Denver, CO, #Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO, and " Division of Pulmonary and Critical Care Medicine, University of Washington Medical ...
Combined intense lifestyle and pharmacologic lipid treatment further
Combined intense lifestyle and pharmacologic lipid treatment further

... for five additional years for coronary artery bypass graft, percutaneous coronary intervention, myocardial infarction, or cardiac death. Patients were categorized blindly according to prospective, predefined criteria as “poor” treatment without diet or lipid drugs, or smoking; “moderate” treatment o ...
Extract from the Clinical Evaluation Report: Adalimumab
Extract from the Clinical Evaluation Report: Adalimumab

... 1. Clinical rationale The sponsor justified the development of adalimumab for the treatment of Non-Radiographic Axial Spondyloarthritis (nr-axSpA) with the following argument: “Currently, there is an unmet medical need in patients with nr-axSpA who have disease features similar to patients with Anky ...
Digital medicine`s march on chronic disease
Digital medicine`s march on chronic disease

... TTM produced a noticeable improvement in physical activity, which has additional health benefits. Developing and deploying TTM cost on the order of a few million dollars, not the billions that are standard for a pharmaceutical product, illustrating the power of digital medicine. The Apple Watch has ...
The Spleen - Home - KSU Faculty Member websites
The Spleen - Home - KSU Faculty Member websites

Research Quarterly
Research Quarterly

... More recently, Bormann et al. (2012) compared the addition of mantram repetition to usual care (i.e., medication and case management) to usual care alone, and found modest improvements in symptoms of depression and PTSD. Without a control for nonspecific aspects of the group meetings, however, it i ...
Harnessing the Inflammatory Reflex: Using Neuromodulation as a
Harnessing the Inflammatory Reflex: Using Neuromodulation as a

... • Inflammatory diseases are a $30B market with significant unmet need • Using neuromodulation to drive the inflammatory reflex has a sound biological foundation: Use in clinic is supported by strong preclinical evidence • This is the first demonstration that an implantable neuromodulation device imp ...
Crohn`s disease and its associated disorders
Crohn`s disease and its associated disorders

... changes of the eyes much more frequently than persons in the general population. The most common conditions include conjunctivitis (inflammation of the membrane lining the eyelids), partial or complete inflammation of the sclera (the white outer wall of the eye = episcleritis or scleritis), iridocyc ...
Treatment of melasma with Pycnogenol
Treatment of melasma with Pycnogenol

... Pycnogenol1 is a standardized extract of the bark of the French maritime pine (Pinus pinaster), a wellknown, potent antioxidant. Studies in vitro show that Pycnogenol1 is several times more powerful than vitamin E and vitamin C. In addition, it recycles vitamin C, regenerates vitamin E and increases ...
Jeopardy
Jeopardy

... What is the Immune system ...
170 - UCC
170 - UCC

... Peripheral neuropathies may either be symmetrical and generalized or focal and multifocal, which is usually a good indicator of the cause of the peripheral nerve disease. Generalized peripheral neuropathy Generalized peripheral neuropathies are symmetrical, and usually due to various systematic illn ...
cystic fibrosis for health professionals
cystic fibrosis for health professionals

... The gene for CF results from a mutation in a single gene on chromosome 7 that encodes the CF transmembrane conductance regulator (CFTR) protein, a chloride channel. As there are over 1,800 mutations (Lobo J, 2012) that can affect the gene, the function of the CFTR protein varies from complete absenc ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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